- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Lipoproteins and Cardiovascular Health
- Cerebrovascular and Carotid Artery Diseases
- Aortic aneurysm repair treatments
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Atrial Fibrillation Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Peripheral Artery Disease Management
- Cardiac Arrhythmias and Treatments
- Cardiovascular and Diving-Related Complications
- Cardiovascular Disease and Adiposity
- Congenital Heart Disease Studies
- Coronary Artery Anomalies
- Cardiac Structural Anomalies and Repair
- Vascular Procedures and Complications
- Blood Pressure and Hypertension Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Vascular anomalies and interventions
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Health and Disease Prevention
Gachon University Gil Medical Center
2016-2025
Busan Medical Center
2025
Gachon University
2015-2024
Deleted Institution
2015-2024
Lodestar Research Corporation (United States)
2023
Yonsei University
1998-2022
Sejong General Hospital
2015-2022
Inha University Hospital
2022
Bucheon University
2022
Jackson and Tull (United States)
2022
Use of intravascular ultrasound (IVUS) promotes better clinical outcomes for coronary intervention in complex lesions. However, randomized data demonstrating the usefulness IVUS are limited lesions treated with drug-eluting stents.To determine whether long-term IVUS-guided stent implantation superior to those angiography-guided patients long lesions.The Impact Intravascular Ultrasound Guidance on Outcomes Xience Prime Stents Long Lesions (IVUS-XPL) randomized, multicenter trial was conducted...
There have been no randomized studies comparing intravascular ultrasound (IVUS)-guided versus conventional angiography-guided chronic total occlusion (CTO) intervention using new-generation drug-eluting stent Therefore, we conducted a prospective, randomized, multicenter trial designed to test the hypothesis that IVUS-guided CTO is superior intervention.After successful guidewire crossing, 402 patients with CTOs were group (n=201) or and secondarily Resolute zotarolimus-eluting stents Nobori...
Abstract Renal denervation is a promising new non-pharmacological treatment for resistant hypertension. However, there lack of data from Asian patients. The REQUIRE trial investigated the blood pressure-lowering efficacy renal in treated patients with hypertension Japan and South Korea. Adults (seated office pressure ≥150/90 mmHg 24-hour ambulatory systolic ≥140 mmHg) suitable artery anatomy were randomized to ultrasound or sham procedure. primary endpoint was change baseline at 3 months. A...
In patients with coronary artery disease, some guidelines recommend initial statin treatment high-intensity statins to achieve at least a 50% reduction in low-density lipoprotein cholesterol (LDL-C). An alternative approach is begin moderate-intensity and titrate specific LDL-C goal. These alternatives have not been compared head-to-head clinical trial involving known disease.To assess whether treat-to-target strategy noninferior of for long-term outcomes disease.A randomized, multicenter,...
Abstract Aims This study evaluated the effect of moderate-intensity statin with ezetimibe combination therapy vs. high-intensity monotherapy among patients diabetes mellitus (DM) and atherosclerotic cardiovascular disease (ASCVD). Methods results was a pre-specified, stratified subgroup analysis DM cohort in RACING trial. The primary outcome 3-year composite death, major events, or non-fatal stroke. Among total patients, 1398 (37.0%) had at baseline. incidence 10.0% 11.3% randomized to...
To compare the long term efficacy and safety of rosuvastatin with atorvastatin treatment in adults coronary artery disease.Randomised, open label, multicentre trial.12 hospitals South Korea, September 2016 to November 2019.4400 (age ≥19 years) disease.Participants were assigned receive either (n=2204) or (n=2196) using 2×2 factorial randomisation.The primary outcome was a three year composite all cause death, myocardial infarction, stroke, any revascularisation. Secondary outcomes endpoints:...
There are few randomised studies concerning the optimal duration of dual antiplatelet therapy (DAPT) for patients who receive a second-generation drug-eluting stent (DES). This trial aimed to investigate safety six-month compared with 12-month DAPT maintenance after DES implantation.A prospective, randomised, multicentre was performed at 10 medical centres. The 1,368 included in study received biolimus-eluting (BES) or zotarolimus-eluting (ZES). primary outcome measured composite major...
High-intensity statin is strongly recommended in patients at very high risk (VHR) of atherosclerotic cardiovascular disease (ASCVD). However, concerns about statin-associated adverse effects result underuse this strategy practice.
Introduction Hypoxic liver injury (HLI) and Killip classification are poor prognostic factors in patients with ST-segment elevation myocardial infarction (STEMI). This study investigates the interrelationship between hypoxic classification. Method results A total of 1,537 STEMI who underwent percutaneous coronary intervention (PCI) from 2007 to 2014 at four tertiary hospitals Incheon-Bucheon province were enrolled this study. The divided into groups based on their presentation emergency room...
Background Coronary artery disease is a global health concern that necessitates treatments, such as percutaneous coronary intervention (PCI) with drug-eluting stents (DES). Recent advancements in biodegradable polymer-coated DES have improved long-term outcomes by reducing neointimal hyperplasia. Superior patients ultrathin-strut sirolimus-eluting Orsiro stent (BP-SES) compared those thick-strut biolimus-eluting BioMatrix (BP-BES) been shown. This study aimed to explore the mechanisms...
Introduction: The INCRAFT™ Stent Graft System is a trimodular, bifurcated, ultra-low-profile endovascular device designed for aneurysm repair in patients with abdominal aortic (AAA). Materials and Methods: study population comprised prospective multi-center cohort (n = 85) single-center retrospective 61) of Korean AAA treated INCRAFT. Postprocedural follow-up involved computed tomography (CT) imaging at 1 12 months post-procedure to monitor dimensions detect any endoleak. Results: mean age...
To investigate the effect of pretreatment with intravenous nicorandil on incidence contrast-induced nephropathy (CIN) in patients renal dysfunction undergoing coronary angiography.This randomized controlled multicenter study enrolled a total 166 (nicorandil n=81; control n=85) an estimated glomerular filtration rate <60 mL/min. Nicorandil 12 mg dissolved 100 mL 0.9% saline was administered intravenously for 30 minutes just prior to angiography group. The same volume only given primary...
Although soluble suppression of tumorigenicity 2 (sST2) in serum is known to be associated with ischemic heart disease and failure, data regarding its prognostic impact ST-segment elevation myocardial infarction (STEMI) limited. We evaluated the impacts sST2 other biomarkers STEMI patients undergoing primary percutaneous coronary intervention (PCI).Consecutive all 323 that underwent PCI were enrolled. Blood tests samples obtained an emergency room. The endpoint was 1-year major adverse...
Dexamethasone (DEX), a non-particulate glucocorticoid (GC) to inhibit anti-inflammatory response, has been widely used for the treatment of various diseases such as arthritis, cancer, asthma, chronic obstructive pulmonary disease, cerebral edema, and multiple sclerosis. However, prolonged and/or high-dose GC therapy can cause serious adverse effects (adrenal insufficiency, hyperglycemia, Cushing's syndrome, osteoporosis, Charcot arthropathy, etc). In this study, developed DEX-carbon nanotube...