A5016982830- Cardiovascular Function and Risk Factors
- Pulmonary Hypertension Research and Treatments
- Blood Pressure and Hypertension Studies
- Cardiac Imaging and Diagnostics
- Heart Failure Treatment and Management
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Lipoproteins and Cardiovascular Health
- Hormonal Regulation and Hypertension
- Cardiovascular Health and Disease Prevention
- Aortic Disease and Treatment Approaches
- Cardiac tumors and thrombi
- Cardiovascular Issues in Pregnancy
- Congenital Heart Disease Studies
- Cardiac pacing and defibrillation studies
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Diabetes Treatment and Management
- Cardiovascular and Diving-Related Complications
- Cardiovascular Disease and Adiposity
- Heart Rate Variability and Autonomic Control
- Atrial Fibrillation Management and Outcomes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Vascular Anomalies and Treatments
- Coronary Artery Anomalies
Gachon University Gil Medical Center
2016-2025
Gachon University
2016-2025
Seoul St. Mary's Hospital
2014-2024
Catholic University of Korea
2024
Yonsei University
1999-2024
University of Ulsan
2012-2023
Asan Medical Center
2012-2023
Ulsan College
2012-2023
Central Research Institute
2023
Deleted Institution
2013-2022
Biological mechanisms underlying statin and angiotensin II type 1 receptor blocker therapies differ. Therefore, we compared vascular metabolic responses to these either alone or in combination hypercholesterolemic, hypertensive patients.This was a randomized, double-blind, placebo-controlled crossover trial with 3 treatment arms (each 2 months) washout periods months). Forty-seven hypertensive, hypercholesterolemic patients were given simvastatin 20 mg placebo, losartan 100 mg, placebo daily...
Cardiovascular disease (CVD) is the leading cause of death and disability worldwide. To provide an overview temporal trends in burden CVD, Korean Society Cardiology has published Korea Heart Disease Fact Sheet 2020.
Protease Ti, a new ATP-dependent protease in Escherichia coli, degrades proteins and ATP linked process, but these two hydrolytic functions are catalyzed by distinct components of the enzyme. To clarify enzyme's specificity role ATP, variety fluorogenic peptides were tested as possible substrates for Ti or its components. rapidly hydrolyzed N-succinyl(Suc)-Leu-Tyr-amidomethylcoumarin (AMC) (Km = 1.3 mM) which is not degraded La, other E. coli. also hydrolyzed, slowly, Suc-Ala-Ala-Phe-AMC...
Differentiating between malignant and benign lesions on the basis of MR images depends experience radiologist. For non-experts, we aimed to develop a simplified systematic MRI approach that uses depth, size heterogeneity T(2) weighted (T(2)WI) differentiate lesions, evaluated its diagnostic accuracy.MR 266 patients with histologically proven soft-tissue tumours extremities (102 malignant, 164 benign) were analysed according depth (superficial or deep), (<50, ≥50 mm) signal intensity...
Isopentenols, such as prenol and isoprenol, are promising advanced biofuels because of their higher energy densities better combustion efficiencies compared with ethanol. Microbial production isopentenols has been developed recently via metabolically engineered E. coli. However, current yields remain low the underlying pathways require systematic optimization.In this study, we targeted coli native 2-methyl-(D)-erythritol-4-phosphate (MEP) pathway its upstream glycolysis for optimization...
Abstract Smartphone technology has spread rapidly around the globe. According to a report released by Korea Information Society Development Institute, about 95% of Koreans aged more than 30 years old owned smartphones. Recently, blood pressure (BP) measurement using photoplethysmography-based smartphone algorithm paired with smartwatch is continuously evolving. In this document, Korean Hypertension intends remark current results / smartwatch-based BP and recommend optimal methods device. We...
Adequate luminal distension is essential for improving adenoma detection during colonoscope withdrawal. A few crossover studies have reported that dynamic position changes maximize and increase rates (ADR). We designed a multicenter, randomized, parallel-group trial to verify the effect of on colonic detection.This study was conducted at six hospitals Catholic University Korea. Patients aged 45-80 years who underwent colonoscopy first time were included. In change group, withdrawal as...
Baseline Characteristics of the Korean Registry Pulmonary Arterial HypertensionDespite recent advances in understanding pathobiology and targeted treatments pulmonary arterial hypertension (PAH), epidemiologic data from large populations have been limited to western countries.The aim Hypertension (KORPAH) was examine epidemiology prognosis patients with PAH.KORPAH designed as a nationwide, multicenter, prospective collection using an internet webserver September 2008 December 2011.A total...
Despite the advancement of targeted therapy for pulmonary arterial hypertension (PAH), poor prognosis remains a reality. Mesenchymal stem cells (MSCs) are one most clinically feasible alternative treatment options. We compared effects adipose tissue (AD)-, bone marrow (BD)-, and umbilical cord blood (UCB)-derived MSCs in rat monocrotaline-induced (PH) model. The greatest improvement right ventricular function was observed UCB-MSCs treated group. group also exhibited terms largest decrease...
This study aimed to evaluate the progress of treatment with intensive targeted therapy in high-risk pulmonary arterial hypertension (PAH) patients and focused on setting an appropriate hemodynamic target vascular resistance (PVR) ≤4 Wood units (WU) mean pressure (mPAP) ≤ 40 mmHg. We retrospectively evaluated PAH who were administered treprostinil at a single tertiary center between January 2020 December 2022. Echocardiography, right heart catheterization, 6-minute walk distance (6MWD), blood...
The Heart Failure Frailty Score (HFFS) is a novel, multidimensional tool to assess frailty in patients with heart failure (HF). It has been developed overcome limitations of existing assessment tools while being practical for clinical use. HFFS reflects the concept as multidimensional, dynamic and potentially reversible state, which increases vulnerability stressors risk poor outcomes HF. was through Delphi consensus process involving 54 international experts. This approach involved...
The effects of hormone replacement therapy (HRT) can affect many aspects relevant to cardiovascular disease, including vasomotor function, inflammation, and hemostasis. Recent studies have demonstrated that current doses HRT exert a mixture both protective adverse effects. In the study, we compared lower (L-HRT) conventional (C-HRT) on variety parameters.This randomized, double-blind, crossover study included 57 women who received micronized progesterone 100 mg with either conjugated equine...
OBJECTIVE—Mechanisms underlying fibric acid and angiotensin II type 1 receptor blocker therapies differ. Signaling from peroxisome proliferator-activated α may cross-talk with the system. We investigated vascular metabolic responses to these either alone or in combination hypertriglyceridemic hypertensive patients. RESEARCH DESIGN AND METHODS—This was a randomized, double-blind, placebo-controlled, cross-over trial three treatment arms (each 2 months) two washout periods months). Forty-four...
Abstract Aim To evaluate the effectiveness of empagliflozin in clinical practice East Asia Empagliflozin Comparative Effectiveness and Safety (EMPRISE) study. Materials methods Data were obtained from Medical Vision database (Japan), National Health Insurance Service (South Korea) (Taiwan). Patients aged ≥ 18 years with type 2 diabetes initiating or a dipeptidyl peptidase‐4 (DPP‐4) inhibitor 1:1 propensity score (PS) matched into sequentially built cohorts new users naïve to both drug...
We sought to assess the association between common antihypertensive drugs and risk of incident cancer in treated hypertensive patients. Using Korean National Health Insurance Service database, incidence was analyzed patients with hypertension who were initially free used following drug classes: Angiotensin-converting enzyme inhibitors (ACEIs); angiotensin receptor blockers (ARBs); beta (BBs); calcium channel (CCBs); diuretics. During a median follow-up 8.6 years, there 4513 (6.4%) overall...