A5100343615- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Glaucoma and retinal disorders
- Liver Disease Diagnosis and Treatment
- Retinal Diseases and Treatments
- Veterinary Oncology Research
- Healthcare and Venom Research
- Liver Disease and Transplantation
- Acupuncture Treatment Research Studies
- Cardiac pacing and defibrillation studies
- Sarcoma Diagnosis and Treatment
- Cardiovascular Function and Risk Factors
- Cardiovascular and Diving-Related Complications
- Cardiac electrophysiology and arrhythmias
- Cardiomyopathy and Myosin Studies
- Pulmonary Hypertension Research and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Cardiac, Anesthesia and Surgical Outcomes
- Traumatic Brain Injury and Neurovascular Disturbances
- Retinal and Macular Surgery
- Aortic Disease and Treatment Approaches
- Corneal surgery and disorders
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
Chungnam National University
2015-2025
Gachon University
2016-2024
Gachon University Gil Medical Center
2016-2024
Chungnam National University Hospital
2015-2024
Konkuk University Medical Center
2024
Kyung Hee University
2024
Konkuk University
2024
Kyungpook National University Hospital
2022
Medical College of Wisconsin
2013-2022
Asan Medical Center
2016-2021
Ferroptosis is a newly defined form of cell death induced by iron-dependent accumulation lethal lipid peroxidation. represent therapeutic strategy to suppress therapy-resistant cancer cells with more property epithelial-mesenchymal transition (EMT). However, epigenetic reprogramming EMT has been rarely studied in the context ferroptosis susceptibility. Therefore, we examined potentiality promoting head and neck (HNC) cells. The effects inducers inhibition or induction were tested HNC lines...
The objective of this study was to compare the incidence post-operative depression in breast cancer patients who have undergone mastectomy with non-breast participants (controls).Using data from Korean Health Insurance Review and Assessment Service (HIRA), we selected 2,130 for national cohort matched these 1:4 8,520 control according age, sex, income, region, pre-operative depression. measured year post-op 10. Mann-Whitney U test used analysis, false-discovery rate applied determine...
The septal extension graft is a very useful method of controlling nasal lengthening and tip projection, rotation, shape by fixing to the septum, which leads strong supporting structure. Enhancing stability important for better long-term outcomes minimizing complications or relapse, even more efficient application these methods needed East Asians who lack enough cartilage be harvested in addition possessing weak framework. In this paper, overcoming drawbacks graft, such as instability, fixed...
Korean Society of Thyroid-Head and Neck Surgery appointed a Task Force to provide guidance on the implementation surgical treatment oral cancer. MEDLINE databases were searched for articles subjects related "surgical management cancer" published in English. Results restricted systematic reviews, randomized control trials/controlled clinical trials, observational studies. The quality evidence was rated with use RoBANS (Risk Bias Assessment Tool Nonrandomized Studies) AMSTAR (A Measurement...
Background: Although the presence of both obesity and reduced muscle mass presents a dual metabolic burden additively has negative effect on variety cardiometabolic parameters, data regarding associations between their combined effects left ventricular diastolic function are limited.This study investigated association ratio skeletal to visceral fat area (SVR) dysfunction (LVDD) in patients with preserved ejection fraction using random forest machine learning. Methods:In total, 1,070...
<h3>Importance</h3> Alopecia areata (AA) is a common autoimmune disease presenting as nonscarring hair loss. Although AA can be associated with other comorbidities or atopic diseases, little known about the risk of cardiovascular diseases in patients AA. <h3>Objective</h3> To investigate acute myocardial infarction (AMI) and profiles (CVRPs) via large-scale epidemiologic study. <h3>Design, Setting, Participants</h3> This was retrospective cohort study using data from Korean National Health...
Hypoplastic left heart syndrome (HLHS) is a clinically and anatomically severe form of congenital disease; however, its etiology remains largely unknown. We previously demonstrated that genetic variants in the MYH6 gene are significantly associated with HLHS. Additionally, induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) from an HLHS-affected family trio (affected parent, unaffected affected proband) carrying MYH6-R443P head domain variant dysmorphic sarcomere structure...
Despite the advancement of targeted therapy for pulmonary arterial hypertension (PAH), poor prognosis remains a reality. Mesenchymal stem cells (MSCs) are one most clinically feasible alternative treatment options. We compared effects adipose tissue (AD)-, bone marrow (BD)-, and umbilical cord blood (UCB)-derived MSCs in rat monocrotaline-induced (PH) model. The greatest improvement right ventricular function was observed UCB-MSCs treated group. group also exhibited terms largest decrease...
To analyze the repeatability of measurements thicknesses macula, retinal nerve fiber layer (RNFL), and ganglion cell inner plexiform (GCIPL) using spectral-domain optical coherence tomography (SD-OCT) in epiretinal membrane (ERM).The prospective study analyzed patients who visited our clinic from June 2013 to January 2014. An experienced examiner measured twice macular cube 512 × 128 optic disc 200 scans. The RNFL, GCIPL were compared intraclass correlation coefficient (ICC) two groups based...
Objective : We retrospectively analyzed the surgical outcomes of 42 patients with growth hormone (GH)-secreting pituitary adenoma to evaluate clinical manifestations and determine which preoperative factors that significantly influence remission.Methods Forty-two GH-secreting underwent transsphenoidal surgery (TSS) between 1995 2007.The patient group included 23 women 19 men, a mean age 40.2 (range 13-61) years, follow-up duration 49.4 3-178) months after operation.For comparable...
To evaluate the clinical benefits and risks of anticoagulation with warfarin in cirrhotic patients atrial fibrillation (AF).A total 465 diagnosed nonvalvular AF were retrospectively analyzed. We compared incidences ischemic stroke major bleeding events between 2 groups examined factors predicting or events.Of AF, 113 (24.3%) received warfarin. Warfarin users had a lower mean Child-Pugh score (6.1 ± 1.5 vs. 7.6 2.6) higher CHA2DS2VASc (2.0 2.5 1.7 1.3) than nonusers (P's < 0.05). Overall,...
Abstract Background & Aims Previous studies demonstrated conflicting results regarding the association between non‐alcoholic fatty liver disease (NAFLD) and atrial fibrillation (AF). The statistical power was not sufficient because of modest sample sizes these studies. We analysed a large population‐based cohort to evaluate NAFLD AF. Methods evaluated 334 280 healthy individuals without comorbidities who underwent National Health check‐ups in South Korea from 2009 2014. defined by...
Heart failure (HF) is relatively common cardiovascular disease with high mortality and morbidity. Although it associated many risk factors, the association between nonalcoholic fatty liver (NAFLD), most chronic disease, HF has not been evaluated in a large-scale cohort study. Thus, we ability of Index (FLI), surrogate marker NAFLD, to predict development healthy individuals.We analyzed FLI new-onset multivariate Cox proportional-hazards models 308,578 persons without comorbidities who...
Purpose: The purpose of this paper was to study the bilateral choroidal thickness (CT) symmetry and differences in healthy individuals using wide-field swept-source optical coherence tomography (SS-OCT). Methods: All participants underwent a 16-mm 1-line scan SS-OCT. CTs were measured at following 12 points: 3 points 900 µm, 1800 2700 µm away from nasal optic disc margin (nasal peripapillary area), 1 point subfovea, 6 subfovea temporal areas (macular 2 peripheral 5400 (peripheral area)....
Premorbid demographic backgrounds of injured individuals are likely to reflect more accurately the status patients with traumatic brian injury (TBI) than clinical factors. However, concrete study about relationship between factors and neurocognitive function in TBI has not been reported. The object this was evaluate effect premorbid on recovery following TBI.From July 1998 February 2007, 293 (male: 228, female: 65) a history head injury, who had recovered from acute phase, were selected our...
Compression of the ulnar nerve in Guyon's canal can result from repeated blunt trauma, fracture hamate's hook, and arterial thrombosis or aneurysm. In addition, conditions such as ganglia, rheumatoid arthritis artery disease rapidly compress canal. A ganglion cyst acutely protrude grow, which also might nerve. So, clinicians should consider a possible underlying cause compression patients with sudden decrease hand strength. We believe that early decompression removal is very important to...
Objective Meningiomas represent 18-20% of all intracranial tumors and have a 20-50% 10-year recurrence rate, despite aggressive surgery irradiation. Hydroxyurea, an inhibitor ribonucleotide reductase, is known to inhibit meningioma cells by induction apoptosis. We report the long-term follow-up result hydroxyurea therapy in patients with recurrent meningiomas. Methods Thirteen WHO grade I or II were treated (1000 mg/m2/day orally divided twice per day) from June 1998 February 2012. Nine...
Although magnetic resonance imaging (MRI) conditional cardiac implantable electronic devices (CIEDs) have become recently available, non-MRI and the presence of epicardial abandoned leads remain a contraindication for MRIs.This was single center retrospective study, evaluating clinical outcomes device parameter changes in patients with CIEDs who underwent an MRI from June 1992 to March 2015. Clinical related information acquired by thorough chart review.A total 40 patients, 38 pacemaker...
Nonalcoholic fatty liver disease (NAFLD) is an excessive accumulation of fat into the as a result increased inflammation and insulin resistance. Although there can be common pathogenic mechanisms for NAFLD hypertension associated with development cardiovascular diseases, little data are showing association between in large-scale cohort study. Thus, we evaluated ability index (FLI), surrogate marker NAFLD, to predict healthy individuals.We included 334,280 individuals without known...
The purpose of this study is to identify the factors affecting failure trials (<50% pain reduction in for trial period) improve success rate spinal cord stimulation (SCS) trial.A retrospective review failed (44 patients, 36.1%) among patients (n=122) who underwent SCS between January 1990 and December 1998 was conducted. We reviewed causes stimulation, age, sex, etiology pain, type electrode, third party support.Of 44 65.9% showed unacceptable relief spite sufficient paresthesia on area with...
Objective : Cardiac dysfunction after aneurysmal subarachnoid hemorrhage (SAH) is associated with elevation of serum cardiac troponin I (cTnI) levels.Elevation cTnI predicts cardiopulmonary and neurological complications, poor outcome.Methods We retrospectively reviewed the medical radiologic records 114 (male 30, female 84) patients who developed SAH between January 2006 June 2007 had no history previous problems.We evaluated their electrocardiography level, which been measured at...
Objectives Acinic cell carcinoma (AciCC) is a rarely encountered malignancy in parotid gland. Because AciCC rare and was recently recognized as the entity of malignancy, has been difficult to study. We aimed analyze diagnosis treatment experience for this our hospital. Methods retrospectively reviewed medical records 20 patients with gland diagnosed from 1990 2009. The preoperative computed tomography scan, fine needle aspiration cytology (FNAC) intraoperative frozen section results were...