A5025463635- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Transplantation: Methods and Outcomes
- Heart Failure Treatment and Management
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Cardiac pacing and defibrillation studies
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Cardiac electrophysiology and arrhythmias
- Cardiac Arrest and Resuscitation
- Organ Transplantation Techniques and Outcomes
- Renal Transplantation Outcomes and Treatments
- Diabetes Treatment and Management
- Cardiac Arrhythmias and Treatments
- Cardiovascular Effects of Exercise
- SARS-CoV-2 and COVID-19 Research
- Animal Virus Infections Studies
- Cardiovascular Disease and Adiposity
- Advanced MRI Techniques and Applications
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Potassium and Related Disorders
- Viral Infections and Immunology Research
- Cardiac and Coronary Surgery Techniques
Tel Aviv University
2010-2025
Rabin Medical Center
2015-2025
University of Missouri–Kansas City
2024
Hôpital Européen Georges-Pompidou
2020
University of Glasgow
2020
Assuta Medical Center
1999
Herzliya Medical Center
1999
Obesity and type 2 diabetes are prevalent in patients with heart failure preserved ejection fraction characterized by a high symptom burden. No approved therapies specifically target obesity-related persons diabetes.
In the STEP-HFpEF trial programme, treatment with semaglutide resulted in multiple beneficial effects patients obesity-related heart failure preserved ejection fraction (HFpEF). Efficacy may vary according to baseline diuretic use, and could modify dose.
Obesity is associated with adverse cardiac remodeling and a key driver for the development progression of heart failure (HF). Once-weekly semaglutide (2.4 mg) has been shown to improve HF-related symptoms physical limitations, body weight, exercise function in patients obesity-related preserved ejection fraction (HFpEF), but effects on structure this population remain unknown.
ObjectiveWe tested whether remote dielectric sensing (ReDS)-directed fluid management reduces readmissions in patients recently hospitalized for heart failure (HF).BackgroundPulmonary congestion is the most common cause of worsening HF leading to hospitalization. Accurate monitoring lung volume may guide optimal treatment and prevent re-hospitalization. ReDS technology a quantitative non-invasive method measuring absolute volume.MethodsPatients acute decompensated were enrolled during their...
BackgroundThe intravenous inodilator levosimendan was developed for the treatment of patients with acutely decompensated heart failure. In last decade scientific and clinical interest has arisen its repetitive or intermittent use in advanced chronic, but not necessarily decompensated, Recent studies have suggested long-lasting favourable effects when administered repetitively, terms haemodynamic parameters, neurohormonal inflammatory markers, outcomes. The existing data, however, requires...
The Heart Failure Frailty Score (HFFS) is a novel, multidimensional tool to assess frailty in patients with heart failure (HF). It has been developed overcome limitations of existing assessment tools while being practical for clinical use. HFFS reflects the concept as multidimensional, dynamic and potentially reversible state, which increases vulnerability stressors risk poor outcomes HF. was through Delphi consensus process involving 54 international experts. This approach involved...
Since the withdrawal of HeartWare (HVAD) from global market, there is an ongoing discussion if and which patients require prophylactically exchange for a HeartMate 3 (HM3). Therefore, it important to study outcome differences between HVAD HM3 patients. Because centres differ in patient selection standard care, we performed propensity score (PS)-based including that implanted both devices aimed identify are at highest risk.
Background. Common immunosuppression strategies after heart transplantation (HTx) are based on accepted target drug levels, disregarding that levels do not correlate with the individual patient's pharmacokinetics or actual immunosuppressive effect patient. The Immuknow assay is used for immune monitoring and management of organ transplant recipients. This study evaluated longitudinal HTx patients throughout various clinical settings. Methods. functional response as measured by was determined...
We describe a Bedouin family with novel autosomal recessive syndrome characterized by dilated cardiomyopathy and septo-optic dysplasia. Genetic analysis revealed homozygous missense mutation in TAX1BP3, which encodes small PDZ domain containing protein implicated regulation of the Wnt/β-catenin signaling pathway, as causative mutation. The affects conserved residue located at core TAX1BP3 binding pocket is predicted to impair nature crucial hydrophobic patch, thereby interrupting structure...
Background Adequate self-care behaviour is essential for patients with a left ventricular assist device (LVAD) to prevent complications, prolong life, and optimise quality of life. However, there were no valid reliable measurements available assess among LVAD. We have previously developed the 33-item LVAD scale. Objectives To evaluate psychometric properties Methods results Data on 127 in Israel, Japan, USA analysed (mean age 51±14.3, 81% male). Exploratory factor analysis extracted three...
Abstract Aims Sexual dysfunction is common among patients with heart failure (HF) and considered an important hamper to quality of life. While implantation left ventricular assist device (LVAD) may prolong improve life in advanced HF, limited data are available on its impact sexual function. The aim this study evaluate function LVAD compare after transplantation (HTx). Methods results activity satisfaction stable durable or HTx were evaluated using a validated questionnaire visual analogue...
We present a morbidly obese 44-year-old female who underwent Thoratec HeartMate II left ventricular assist device implantation. The patient subsequently laparoscopic sleeve gastrectomy and removal of the LVAD following improvement in her cardiac function. doi: 10.1111/jocs.12404 (J Card Surg 2014;29:740–742)