- Health disparities and outcomes
- Heart Failure Treatment and Management
- Cardiovascular Health and Risk Factors
- Cardiac Health and Mental Health
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Advanced Radiotherapy Techniques
- Air Quality and Health Impacts
- Frailty in Older Adults
- Acute Myocardial Infarction Research
- Climate Change and Health Impacts
- Nutrition and Health in Aging
- Health Systems, Economic Evaluations, Quality of Life
- Physical Activity and Health
- Global Health Care Issues
- Lipoproteins and Cardiovascular Health
- Health, psychology, and well-being
- Chronic Disease Management Strategies
- Glaucoma and retinal disorders
- Blood Pressure and Hypertension Studies
- Cardiovascular and exercise physiology
- Bone health and osteoporosis research
- Cardiac Structural Anomalies and Repair
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Sarcoma Diagnosis and Treatment
Tel Aviv University
2016-2025
Mayo Clinic
2008-2021
University of California, Berkeley
2021
Kaiser Permanente
2021
Berkeley Public Health Division
2021
McGill University
2020
Rabin Medical Center
2019
Mayo Clinic in Arizona
2007-2018
Mayo Clinic in Florida
2007-2017
Gerber Technology (United States)
2017
IMPORTANCE Heart failure (HF) is commonly referred to as an epidemic, posing major clinical and public health challenges.Yet, contemporary data on its magnitude implications are scarce.OBJECTIVE To evaluate recent trends in HF incidence outcomes overall by preserved ejection fraction (HFpEF) or reduced (HFrEF).
Background— In 2000, the definition of myocardial infarction (MI) changed to rely on troponin rather than creatine kinase (CK) and its MB fraction (CK-MB). The implications this change trends in MI incidence outcome are not defined. Methods Results— This was a community study 2816 patients hospitalized with incident from 1987 2006 Olmsted County, Minnesota, prospective measurements CK-MB August 2000 forward. Outcomes were incidence, severity, survival. After introduced, 278 (25%) 1127 MIs...
Mortality in heart failure (HF) remains high but causes of death are incompletely defined. As HF is heterogeneous syndrome categorized according to ejection fraction (EF), the association between EF and important, yet elusive.Community subjects with were classified preserved (> or =50%) reduced (<50%). Deaths as coronary disease (CHD), other cardiovascular non-cardiovascular. Among 1063 persons HF, 45% had less risk factors than those EF. At 5 years, survival was (95% CI 43%-49%) 43% deaths...
Background— Contemporary data are lacking on the prognostic importance of heart failure (HF) after myocardial infarction (MI). We evaluated impact HF post MI according to preserved/reduced ejection fraction and timing its occurrence. Methods Results— All Olmsted County, Minnesota, residents (n=2596) with incident diagnosed in 1990 2010 no prior were followed through March 2013. Cox models used examine (1) hazard ratios for death associated type (2) secular trends survival by status. During a...
In Brief PURPOSE: To assess the intraoperator repeatability and interoperator reproducibility of central corneal thickness measurements by Pentacam Scheimpflug imaging system (Oculus) optical low-coherence reflectometer (OLCR) pachymeter (Haag-Streit) to compare them with those ultrasound (US) pachymetry. SETTING: Assaf Harofe Medical Center Ophthalmology Outpatient Clinic, Zerifin, Israel. METHODS: Repeatability was determined from 10 successive in each 4 healthy patients. Reproducibility...
To compare parameters of biomechanical response the human cornea measured as corneal hysteresis (CH) and resistance factor (CRF) in patients with diabetes mellitus healthy control subjects.Department Ophthalmology, Assaf Harofeh Medical Center, Zerifin, Israel.In right eye each participant, CH, CRF, Goldmann-correlated intraocular pressure (IOPg), corneal-compensated (IOPcc) were Ocular Response Analyzer. Central thickness (CCT) was by ultrasonic pachymetry Goldmann applanation tonometry...
Although age-adjusted cardiovascular disease (CVD) mortality has declined over the past decades, controversies remain about whether this trend was similar across locations of death and categories existence age sex disparities.We examined CVD trends in Olmsted County, Minnesota, between 1979 2003 using defined by American Heart Association, including coronary heart (CHD), non-CHD diseases heart, noncardiac circulatory diseases. Data on demographics, cause, location all 6378 residents who died...
Neighborhood of residence has been suggested to affect cardiovascular risk above and beyond personal socioeconomic status (SES). However, such data are currently lacking for patients with myocardial infarction (MI). We examined all-cause cardiac mortality according neighborhood SES in a cohort MI patients.Consecutive < or =65 years age discharged from 8 hospitals central Israel after incident 1992 1993 were followed up through 2005. Individual obtained at study entry, including education,...
Major changes have recently occurred in the epidemiology of myocardial infarction (MI) that could possibly affect outcomes such as heart failure (HF). Data describing trends HF after MI are scarce and conflicting do not distinguish between preserved reduced ejection fraction (EF). We evaluated temporal MI. All residents Olmsted County, Minnesota (n = 2,596) who had a first-ever diagnosed 1990–2010 no prior were followed-up through 2012. Framingham Heart Study criteria used to define HF,...
To evaluate the feasibility of tacrolimus 0.03% dermatological ointment (Protopic) in treatment intractable allergic conjunctivitis.Twenty patients (mean age 10.8 years, range 6-26) with conjunctivitis were enrolled an open-label study. Tacrolimus was applied into conjunctival sac both eyes twice daily for 8 weeks, followed by a 2-week washout period. Other ocular medications discontinued. Conjunctivitis severity recorded composite subjective/objective score (chemosis, tarsal papillary size,...
We evaluated the role of lipoprotein-associated phospholipase A2 (Lp-PLA2), an inflammatory biomarker, in defining risk after myocardial infarction (MI).Olmsted County, Minn, residents who experienced MI meeting standardized criteria between 2003 and 2005 (n = 271) were prospectively identified followed. Lp-PLA2 levels measured at baseline along with traditional indicators. was modestly associated total low-density lipoprotein cholesterol, smoking, age (inversely) but not characteristics or...
BackgroundPost-myocardial infarction (MI) depression and anxiety were found to predict prognosis quality of life.
Whether the extent of coronary artery disease (CAD) is associated with occurrence heart failure (HF) after myocardial infarction (MI) not known. Furthermore, whether this association might differ by HF type according to preserved or reduced ejection fraction (EF) has yet be determined.To evaluate in a community cohort patients incident (first-ever) MI angiographic CAD subsequent and examine prognostic role subtypes: EF EF.A population-based study was conducted 1922 residents Olmsted County,...