A5101424469- Ovarian cancer diagnosis and treatment
- Dermatologic Treatments and Research
- Hair Growth and Disorders
- Endometrial and Cervical Cancer Treatments
- Lipoproteins and Cardiovascular Health
- Asian Culture and Media Studies
- Credit Risk and Financial Regulations
- Antimicrobial Resistance in Staphylococcus
- Endometriosis Research and Treatment
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Bacterial Identification and Susceptibility Testing
- Adipokines, Inflammation, and Metabolic Diseases
- Diverse Topics in Contemporary Research
- melanin and skin pigmentation
- Cervical Cancer and HPV Research
- Probability and Risk Models
- Migration, Ethnicity, and Economy
- Vascular Anomalies and Treatments
- Blood Pressure and Hypertension Studies
- Hormonal and reproductive studies
- Skin Protection and Aging
- Jewish Identity and Society
- Muscle activation and electromyography studies
- Cultural Studies and Interdisciplinary Research
- Menopause: Health Impacts and Treatments
Kangwon National University Hospital
2023-2025
CHA University
2007-2024
CHA Bundang Medical Center
2024
Yonsei University
2024
Severance Hospital
2024
Uijeongbu St. Mary's Hospital
2024
Catholic University of Korea
2024
Bucheon University
2024
Soonchunhyang University
2024
Amorepacific (South Korea)
2017-2022
This study investigates the pattern of disease recurrence and identifies clinicopathologic prognostic factors for patients with International Federation Gynecology Obstetrics (FIGO) stage IB IIA cervical carcinoma treated laparoscopic/robotic radical hysterectomy (LRH/RRH).We conducted a retrospective analysis 128 FIGO cancer. Preoperative examination did not uncover definitive evidence parametrial invasion or lymph node metastasis in any patients; therefore, all underwent LRH/RRH...
Abstract Background Despite the widespread use of vancomycin in methicillin-resistant Staphylococcus aures (MRSA) infections, there is still a lack clinical data elucidating optimal target concentration pediatric population. Methods From September 2013 to December 2021, retrospective analysis was conducted on patients (3 months- 18 years age) with MRSA bacteremia. Vancomycin area under concentration-time curve (AUC) estimated by Bayesian software. Results A total 56 bacteremia were included,...
Hypertension is characterized by endothelial dysfunction and frequently clusters with metabolic disorders that are insulin resistance (1,2). These comorbidities may be explained, in part, reciprocal relationships between (1). By contrast calcium channel blockers (CCBs), treatment of hypertension β-blockers diuretics associated a higher risk type 2 diabetes (3). This advantage CCBs relate to specific mechanisms target the vicious synergy resistance. activate nitric oxide (NO) synthase vitro...
Berberine, an isoquinoline alkaloid, has a wide range of beneficial properties, including anti-bacterial, anti-inflammatory, anti-cancer, and cholesterol-lowering effects. Recently findings suggest that berberine improves glucose lipid metabolism disorders. In the present study, we examined mechanism underlying inhibitory effect on α-melanocyte-stimulating hormone (α-MSH)-stimulated B16F10 melanoma cells. The results showed attenuated α-MSH induction microphthalmia-associated transcription...
Objective:The purpose of this study is to validate the Gynecologic Oncology Group (GOG) criteria for adjuvant treatment in a different cohort patients and evaluate simplified risk predicting prognosis tailoring with surgically staged endometrial cancer.Methods: We performed retrospective analysis 261 consecutive cancer between January 2000 February 2013.All had complete staging procedures were according 2009 International Federation Gynecology Obstetrics system.Clinical pathologic data...
Statin and angiotensin II type 1 receptor blocker therapy improves endothelial dysfunction using distinct mechanisms. We evaluated simultaneous vascular metabolic responses to pravastatin valsartan therapy, alone or in combination, hypercholesterolemic patients. Forty-eight patients (23 had syndrome) were given 40 mg placebo, 160 mg, placebo daily during each 2-month treatment period a randomized, single-blind, placebo-controlled, crossover trial with three arms two washout periods (each 2...
The consensus guideline development committee of Korean Society Gynecologic Oncology was reconvened in March 2012.The consisted 36 experts representing 12 university hospitals and professional organizations.The objective this to develop standardized guidelines for cervical cancer screening tests women distribute these every clinician, eventually improving the quality medical care.Since establishment committee, evidence-based have either been developed de novo considering specific situations...
Aims We have previously reported that lower doses of hormone therapy (L-HT) and tibolone different effects on markers cardiovascular disease when compared with conventional HT. The objective was to compare the L-HT lipid profile, vasodilation, factors associated inflammation haemostasis.
It is well known that Panax ginseng (PG) has various pharmacological effects such as anti-aging and anti-inflammation. In a previous study, the authors identified PG extract induced hair growth by means of mechanism similar to minoxidil. present inhibitory effect on Dickkopf-1 (DKK-1)-induced catagen-like changes in follicles (HFs) was investigated addition underlying action. The cell proliferation, anti-apoptotic effect, were observed using cultured outer root sheath (ORS) keratinocytes...
It has been established that glycosaminoglycans (GAGs) serve an important role in protecting the skin against effects of aging. A previous clinical trial by our group identified a cream containing GAGs reduced wrinkles and increased elasticity, dermal density tightening. However, exact molecular mechanism underlying anti‑aging effect not yet fully elucidated. The present study assessed influence on cell viability, collagen synthesis synthesis‑associated signaling pathways tumor necrosis...
Recently, various immunosuppressant drugs have been shown to induce hair growth in normal as well alopecia areata and androgenic alopecia; however, the responsible mechanism has not yet fully elucidated. In this study, we investigate influence of mycophenolate (MPA), an immunosuppressant, on proliferation human dermal papilla cells (hDPCs) follicles following catagen induction with interferon (IFN)-γ. IFN-γ was found reduce β-catenin, activator follicle growth, activate glycogen synthase...
ABSTRACT Large cell neuroendocrine carcinoma (LCNEC) of the lung is a rare and aggressive tumour with poor prognosis. Lung cancer metastases to prostate are also uncommon, usually found incidentally during autopsy. Most reported primary cancers prostatic small carcinomas, from LCNEC have not been previously. This case report describes 70‐year‐old man in prostate, brain, bone, liver lymph nodes.
The extremal dependence of defaults, and negative correlation between defaults their recovery rates, are major interest in modeling portfolio credit risk. In order to incorporate these two features, we propose a risk model with random rates. proposed is an extension the traditional t-copula for constant A skew-normal copula adopted represent dependent our model, various types dependency rates possible, including inverse relation. We also conditional Monte Carlo simulation algorithm...
Androgenic alopecia is a hair loss disease mediated by dihydrotestosterone (DHT) and currently treated using minoxidil, finasteride, or low-level laser therapy. However, these treatments have side-effects, indicating the need for an alternative treatment. In present study, it was demonstrated that inaudible sound at 30 kHz significantly induced proliferative anti-apoptotic effects in human dermal papilla cells (hDPCs) outer root sheath keratinocytes. Cell viability assay, ELISA, reverse...
BACKGROUNDMetastases to the breast from extramammary malignancies are very rare. We describe here clinicopathologic features of metastatic tumors that were identified in Korean patients at a single institute.METHODSWe analyzed data who diagnosed between January 1989 and April 2009 Asan Medical Center.RESULTSOnly 31 (0.21%) with metastases over 20-year period, 29 them had available data. The mean time diagnosis metastasis after primary malignancy was 21 months (range, 0 102 months). most...