A5100429325- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Cervical Cancer and HPV Research
- Uterine Myomas and Treatments
- PARP inhibition in cancer therapy
- Cancer Genomics and Diagnostics
- Cancer Immunotherapy and Biomarkers
- Endometriosis Research and Treatment
- Intraperitoneal and Appendiceal Malignancies
- Gastric Cancer Management and Outcomes
- Minimally Invasive Surgical Techniques
- Pancreatic and Hepatic Oncology Research
- Genetic factors in colorectal cancer
- Gastrointestinal Tumor Research and Treatment
- Immune Cell Function and Interaction
- BRCA gene mutations in cancer
- Cancer-related molecular mechanisms research
- Radiomics and Machine Learning in Medical Imaging
- Colorectal and Anal Carcinomas
- Reproductive System and Pregnancy
- Renal cell carcinoma treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Sarcoma Diagnosis and Treatment
- Immunotherapy and Immune Responses
- Lymphoma Diagnosis and Treatment
Yonsei University
2016-2025
Severance Hospital
2015-2025
Texas Tech University Health Sciences Center
2025
Dong-Eui University
2024
Seoul National University
2013-2024
Seoul Veterans Hospital
2019-2024
Korea University Medical Center
2024
Jikei University School of Medicine
2023
University of Ulsan
2002-2023
Asan Medical Center
2002-2023
Although microRNAs have recently been recognized as riboregulators of gene expression, little is known about microRNA expression profiles in serous ovarian carcinoma. We assessed the and association between prognosis carcinoma.Twenty patients diagnosed with carcinoma eight treated for benign uterine disease December 2000 September 2003 were enrolled this study. The examined using DNA microarray Northern blot analyses.Several differentially expressed compared normal tissues, including miR-21,...
Background Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis. The high risk of recurrence following surgical resection provides the rationale for adjuvant therapy. However, only subset patients benefit from Identification molecular markers to predict treatment outcome is therefore warranted. aim present study was evaluate whether expression novel candidate biomarkers, including microRNAs, can clinical in PDAC treated with Methodology/Principal Findings Formalin-fixed paraffin...
The functions of many long non-coding RNAs (lncRNAs) in human cancers remain to be clarified. lncRNA Hox transcript antisense intergenic RNA (HOTAIR) has been reported reprogram chromatin organization and promote breast colorectal cancer metastasis, the involvement lncRNAs cervical is just beginning studied. In present study, we examined expression functional role HOTAIR cancer. was determined tissues (n=111) corresponding normal (n=40) by using real-time polymerase chain reaction, its...
A variety of tumors, including primary malignant secondary and benign can occur in the tracheobronchial tree. Primary tumors commonly originate from surface epithelium or salivary glands, whereas most arise mesenchymal tissue. At computed tomography (CT), manifest as a polypoid lesion, focal sessile eccentric narrowing airway lumen, circumferential wall thickening. fluorine 18 fluorodeoxyglucose (FDG) positron emission (PET), squamous cell carcinomas show high uptake, adenoid cystic...
Purpose: To describe the computed tomographic (CT) findings of ectopic pancreas and to identify features that differentiate it from other similarly manifesting gastric submucosal tumors such as gastrointestinal stromal tumor (GIST) leiomyoma, which are most common tumors. Materials Methods: This retrospective study was approved by institutional review board did not require informed consent. CT images pathologically proved pancreases (n = 14), GISTs 33), leiomyomas 7) in stomach duodenum were...
Epithelial-mesenchymal transition (EMT) is defined as switching of polarized epithelial cells to a migratory fibroblastoid phenotype. EMT known be involved in the progression and metastasis various cancers. The aim was evaluate expression EMT-related proteins gastric carcinoma (GC).The nine GC tissues 598 patients evaluated by immunohistochemistry using tissue array method. In addition, clinicopathological characteristics survival were compared with proteins. Loss protein and/or acquisition...
Kim M A, Lee H‐J, Yang H‐K, Bang Y‐J & W H (2011) Histopathology 59 , 822–831 Heterogeneous amplification of ERBB2 in primary lesions is responsible for the discordant status and metastatic gastric carcinoma Aims: To determine extent HER2 homogeneity/heterogeneity versus (GC). Materials results: The human epidermal growth factor receptor 2 (HER2) was evaluated by immunohistochemistry (IHC) fluorescence in‐situ hybridization (FISH). Four separate cohorts consisting GC alone or paired with...
The survival of patients with ovarian cancer has improved because surgery and chemotherapy. This study aimed to estimate the changes in rates among Korean women prior introduction targeted therapy for cancer.Data were obtained from Korea Central Cancer Registry regarding who diagnosed epithelial between 1995 2014. relative calculated 5-year periods using Ederer II method. Cox proportional hazard models created assess associations demographic clinicopathological factors survival.During...
To investigate the question of whether electroacupuncture (EA) promotes functional recovery via enhancement proliferation and differentiation neuronal stem cells (NSCs) in ischemic stroke, EA stimulation with 2 Hz was applied at bilateral acupoints to Baihui (GV20) Dazhui (GV14) middle cerebral artery occlusion (MCAO) mice. improved neuromotor function cognitive ability after stroke. resulted an increase number proliferated cells, especially subventricular zone (SVZ) ipsilateral hemisphere....
Abstract Obesity is a major health problem and known to be closely associated with metabolic diseases. Abnormal hepatic accumulation of fat causes fatty liver or steatosis, long-term consumption high-fat diet key obesity-causing factor. Recent studies have demonstrated that probiotics such as Lactobacillus strains , exert an anti-obesity effect by regulating adipogenesis. However, it still unknown how the can reduce abdominal volume expression lipogenic genes. Therefore, we evaluated...
The purpose of this study was to describe the MRI features small solid pseudopapillary tumors useful for differentiating these from other pancreatic tumors.Forty-five patients (18 men, 27 women; mean age, 59 ± 11.7 years) with 45 smaller than 3 cm in diameter registered 2000 2009 were included. Twenty-two adenocarcinomas, 12 endocrine tumors, and 11 tumors. Two radiologists analyzed MR images morphologic features, signal intensity lesion on unenhanced images, dynamic enhancement pattern....
Clinical practice guidelines for gynecologic cancers have been developed by many organizations.Although these much in common terms of the standard care uterine corpus cancer, that reflect characteristics patients and healthcare insurance systems are needed each country.The Korean Society Gynecologic Oncology (KSGO) published first edition cancer treatment late 2006; second was released July 2010 as an evidence-based recommendation.The Guidelines Revision Committee established 2015 decided to...
The chemotherapy response score (CRS) system based on histopathological examination has been recently proposed for tubo-ovarian high-grade serous carcinoma (HGSC) to assess neoadjuvant (NAC). This study was aimed at validating the CRS in an external cohort of HGSC patients. included 110 patients who underwent NAC followed by interval debulking surgery. 3-tiered omental and adnexal tissue sections determined 3 independent pathologists. Differences patient outcomes according were analyzed....