A5016493985- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- Advanced MRI Techniques and Applications
- Cardiovascular Function and Risk Factors
- Medical Imaging Techniques and Applications
- Cardiovascular Disease and Adiposity
- Advanced X-ray and CT Imaging
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrhythmias and Treatments
- Hemodynamic Monitoring and Therapy
- Aortic Disease and Treatment Approaches
- Venous Thromboembolism Diagnosis and Management
- Ultrasound and Hyperthermia Applications
- Cerebrovascular and Carotid Artery Diseases
- Heart Rate Variability and Autonomic Control
- Cardiac electrophysiology and arrhythmias
- Coronary Artery Anomalies
- Cardiac Arrest and Resuscitation
- Antiplatelet Therapy and Cardiovascular Diseases
- Healthcare cost, quality, practices
- Peripheral Artery Disease Management
- Infective Endocarditis Diagnosis and Management
- Cardiac and Coronary Surgery Techniques
Imaging Center
2010-2025
Memorial Hermann
2016-2025
The University of Texas Health Science Center at Houston
2016-2025
Milton Keynes Hospital
2022-2024
Onze Lieve Vrouwziekenhuis Hospital
2014-2023
University of Houston
2022
University of Buckingham
2022
The University of Texas Health Science Center at San Antonio
2019
Catharina Ziekenhuis
2016-2018
Radboud University Nijmegen
2016-2018
Stenting an angiographically intermediate but functionally non-significant stenosis is controversial. Nevertheless, it has been questioned if deferral of a lesion on the basis fractional flow reserve (FFR) measurement, safe, especially long term. Five-year follow-up DEFER trial showed that outcome after percutaneous coronary intervention (PCI) based FFR ≥ 0.75 excellent and was not improved by stenting. The aim this study to investigate validity position very In 325 patients scheduled for...
Randomised controlled trials have reported instantaneous wave-free ratio (iFR) to be non-inferior fractional flow reserve (FFR) for major adverse cardiovascular events at one year; however, iFR is limited by sensitive landmarking of the pressure waveform, and assumption that maximal minimal resistance occur during a fixed period diastole. We sought validate resting full-cycle (RFR), novel non-hyperaemic index coronary stenosis severity based on unbiased identification lowest distal aortic...
BACKGROUND: Diffuse coronary artery disease affects the safety and efficacy of percutaneous intervention (PCI). Pathophysiologic patterns can be quantified using fractional flow reserve (FFR) pullbacks incorporating pullback pressure gradient (PPG) calculation. This study aimed to establish capacity PPG predict optimal revascularization procedural outcomes. METHODS: prospective, investigator-initiated, single-arm, multicenter enrolled patients with at least one epicardial lesion an FFR ≤0.80...
Cardiac PET combined with CT is rapidly expanding despite artifactual defects and false-positive results due to misregistration of attenuation correction data-the frequency, cause, which remain undetermined.Two hundred fifty-nine consecutive patients underwent diagnostic rest-dipyridamole myocardial perfusion PET/CT using (82)Rb, a 16-slice scanner, helical breathing also at end-expiratory breath-hold, averaged cine data during breathing. Misregistration on superimposed fusion images was...
Background— Fractional flow reserve (FFR) measurement of intermediate coronary stenoses is recommended by guidelines when demonstration ischemia noninvasive testing unavailable. The study aims to evaluate the penetration this recommendation into current thinking about revascularization strategies for stable artery disease. Methods and Results— International Survey on Interventional Strategy was conducted via a web-based platform. First, participants’ experiences in interventional cardiology...
This study compared the diagnostic performance with adenosine-derived fractional flow reserve (FFR) ≤0.8 of contrast-based FFR (cFFR), resting distal pressure (Pd)/aortic (Pa), and instantaneous wave-free ratio (iFR). objectively identifies lesions that benefit from medical therapy versus revascularization. However, requires maximal vasodilation, usually achieved adenosine. Radiographic contrast injection causes submaximal coronary hyperemia. Therefore, intracoronary could provide an easy...
Because randomized coronary revascularization trials in stable artery disease (CAD) have shown no reduced myocardial infarction (MI) or mortality, the threshold of quantitative perfusion severity was analyzed for association with death, MI, stroke after within 90 d PET. <b>Methods:</b> In a prospective long-term cohort CAD, regional, artery-specific, by PET, and all-cause (DMS) at 9-y follow-up (mean ± SD, 3.0 2.3 y) were multivariate Cox regression models propensity analysis....
Background— Fractional flow reserve (FFR)-guided coronary artery bypass graft (CABG) surgery has been associated with lower number of anastomoses, rate on-pump surgery, and higher patency as compared angiography-guided CABG surgery. However, no clinical benefit reported to date. Methods Results— Consecutive patients (n=627) treated by between 2006 2010 were retrospectively included. In 198 patients, at least 1 stenosis was grafted according FFR (FFR-guided group), whereas in 429 all stenoses...
The interplay between coronary hemodynamics and plaque characteristics remains poorly understood.The aim of this study was to compare atherosclerotic phenotypes focal diffuse artery disease (CAD) defined by hemodynamics.This multicenter, prospective, single-arm conducted in 5 countries. Patients with functionally significant lesions based on an invasive fractional flow reserve ≤0.80 were included. Plaque analysis performed using computed tomography angiography optical coherence tomography....
This study sought to examine the clinical performance of and theoretical basis for instantaneous wave-free ratio (iFR) approximation fractional flow reserve (FFR).Recent work has proposed iFR as a vasodilation-free alternative FFR making mechanical revascularization decisions. Its fundamental is assumption that diastolic resting myocardial resistance equals mean hyperemic resistance.Pressure-only combined pressure-flow data from several centers were studied both empirically by using...