A5023500010- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cerebrovascular and Carotid Artery Diseases
- Peripheral Artery Disease Management
- Cardiac Valve Diseases and Treatments
- Aortic aneurysm repair treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Function and Risk Factors
- Advanced MRI Techniques and Applications
- Cardiac Arrhythmias and Treatments
- Cardiovascular Health and Disease Prevention
- Optical Coherence Tomography Applications
- Vascular Procedures and Complications
- Acute Kidney Injury Research
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Disease and Adiposity
- Aortic Thrombus and Embolism
- Hemodynamic Monitoring and Therapy
- Coronary Artery Anomalies
- Cardiac electrophysiology and arrhythmias
- Chronic Kidney Disease and Diabetes
- Healthcare Policy and Management
- Cardiac Arrest and Resuscitation
St. Francis Hospital
2017-2025
Cardiovascular Research Foundation
2016-2025
St. Francis Hospital
2017-2025
St Francis Chronic Hospital
2019-2024
St Francis’ Hospital
2019-2024
New York Institute of Technology
2024
Columbia University
2019-2023
Hospital Clínico San Carlos
2023
Universidad Complutense de Madrid
2023
St. Francis Hospital
2021-2022
Coronary revascularization guided by fractional flow reserve (FFR) is associated with better patient outcomes after the procedure than angiography alone. It unknown whether instantaneous wave-free ratio (iFR), an alternative measure that does not require administration of adenosine, will offer benefits similar to those FFR.
Stent thrombosis (ST) is a rare but devastating complication of coronary stent implantation, occurring in 0.5% to 1.9% patients with bare metal stents. The incidence ST drug-eluting stents less well studied, particularly among outside clinical trials.The aim this study was evaluate the and potential risk factors for receiving sirolimus-eluting (SES) "real world" after commercial release United States April 2003. All 652 who underwent SES implantation (776 lesions treated) at our institution...
Measuring fractional flow reserve (FFR) with a pressure wire remains underutilized because of the invasiveness guide placement or need for hyperemic stimulus. FFR derived from routine coronary angiography (FFRangio) eliminates both these requirements and displays values entire tree. The FFRangio Accuracy versus Standard (FAST-FFR) study is prospective, multicenter, international trial primary goal determining accuracy FFRangio.Coronary was performed in fashion patients suspected artery...
The purpose of this study was to assess the diagnostic accuracy instantaneous wave-free ratio (iFR) characterize, outside a pre-specified range values, stenosis severity, as defined by fractional flow reserve (FFR) ≤0.80, in prospective, independent, controlled, core laboratory–based environment. Studies with methodological heterogeneity have reported some discrepancies classification agreement between iFR and FFR. ADVISE II (ADenosine Vasodilator Independent Stenosis Evaluation II) designed...
Randomised controlled trials have reported instantaneous wave-free ratio (iFR) to be non-inferior fractional flow reserve (FFR) for major adverse cardiovascular events at one year; however, iFR is limited by sensitive landmarking of the pressure waveform, and assumption that maximal minimal resistance occur during a fixed period diastole. We sought validate resting full-cycle (RFR), novel non-hyperaemic index coronary stenosis severity based on unbiased identification lowest distal aortic...
The clinical value of fractional flow reserve and non-hyperaemic pressure ratios are well established in determining an indication for percutaneous coronary intervention (PCI) patients with artery disease (CAD). In addition, over the last 5 years we have witnessed a shift towards use physiology to enhance procedural planning, assess post-PCI functional results, guide PCI optimisation. this regard, studies reported compelling data supporting longitudinal vessel analysis, obtained guidewire...
BACKGROUND: Diffuse coronary artery disease affects the safety and efficacy of percutaneous intervention (PCI). Pathophysiologic patterns can be quantified using fractional flow reserve (FFR) pullbacks incorporating pullback pressure gradient (PPG) calculation. This study aimed to establish capacity PPG predict optimal revascularization procedural outcomes. METHODS: prospective, investigator-initiated, single-arm, multicenter enrolled patients with at least one epicardial lesion an FFR ≤0.80...
Long-term data on safety and efficacy of instantaneous wave-free ratio (IFR) vs fractional flow reserve (FFR) in guiding percutaneous coronary intervention (PCI) is lacking. This study sought to evaluate the 5-year clinical outcomes IFR- FFR-guided PCI a real-world setting. We assessed all patients undergoing IFR or FFR assessment between January 1, 2014, February 16, 2022, using from SWEDEHEART (Swedish Web-System for Enhancement Development Evidence-Based Care Heart Disease Evaluated...
Background Large discrepancies exist concerning the incidence of myocardial bridging. This has been reported to be 0·5%–2·5% following coronary angiography but 15%–85% autopsy. The purpose study was use intravascular ultrasound and intracoronary Doppler morphology flow characteristics bridging in order find feasible parameters this syndrome.
The aim of this study was to investigate the clinical outcomes patients deferred from coronary revascularization on basis instantaneous wave-free ratio (iFR) or fractional flow reserve (FFR) measurements in stable angina pectoris (SAP) and acute syndromes (ACS). Assessment stenosis severity with pressure guidewires is recommended determine need for myocardial revascularization. safety deferral pooled per-protocol population (n = 4,486) DEFINE-FLAIR (Functional Lesion Intermediate Stenosis...
The study sought to determine the coronary flow characteristics of angiographically intermediate stenoses classified as discordant by fractional reserve (FFR) and instantaneous wave-free ratio (iFR).Discordance between FFR iFR occurs in up 20% cases. No comparisons have been reported FFR/iFR unobstructed vessels.Baseline hyperemic velocity (CFR) were compared across 5 vessel groups: FFR+/iFR+ (108 vessels, n = 91), FFR-/iFR+ (28 24), FFR+/iFR- (22 22), FFR-/iFR- (208 154), an group (201...
Filtration Efficiency of Hospital Face Mask Alternatives Available for Use During the COVID-19 Pandemic
We aimed to evaluate the effectiveness of excimer laser coronary angioplasty (ELCA) treat in-stent restenosis (ISR) due peri-stent calcium-related stent underexpansion as assessed by optical coherence tomography (OCT).We studied 81 patients (81 lesions with ISR, underexpansion, and calcium >90°) who underwent OCT imaging both pre post percutaneous intervention compared treated ELCA (n=23) vs. without (n=58). use was associated more fracture (ELCA: 61%, non-ELCA: 12%, p<0.01), larger final...