A5045471105- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Valve Diseases and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Mechanical Circulatory Support Devices
- Vascular Procedures and Complications
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Aortic aneurysm repair treatments
- Peripheral Artery Disease Management
- Heart Failure Treatment and Management
- Venous Thromboembolism Diagnosis and Management
- Cardiac pacing and defibrillation studies
- Adipose Tissue and Metabolism
- Erythropoietin and Anemia Treatment
- COVID-19 Clinical Research Studies
- Sepsis Diagnosis and Treatment
- Genetics, Aging, and Longevity in Model Organisms
- Mechanical Failure Analysis and Simulation
- Regulation of Appetite and Obesity
- Statistical Methods in Clinical Trials
- Infection Control and Ventilation
- Chemotherapy-induced cardiotoxicity and mitigation
Rabin Medical Center
2015-2024
Tel Aviv University
2015-2024
Lev Hasharon Hospital
2019-2024
Royal Brompton Hospital
2019
Assistance Publique – Hôpitaux de Paris
2019
Hôpital Bichat-Claude-Bernard
2019
Inserm
2019
Stanford University
2019
Université Paris Cité
2019
Massachusetts General Hospital
2015
Measuring fractional flow reserve (FFR) with a pressure wire remains underutilized because of the invasiveness guide placement or need for hyperemic stimulus. FFR derived from routine coronary angiography (FFRangio) eliminates both these requirements and displays values entire tree. The FFRangio Accuracy versus Standard (FAST-FFR) study is prospective, multicenter, international trial primary goal determining accuracy FFRangio.Coronary was performed in fashion patients suspected artery...
AimsThe pathogenesis of late coronary stent thrombosis may be related to impaired arterial healing. Endothelial progenitor cells (EPCs) have been shown play an important role in repair and re-endothelialization following vascular injury. We hypothesized that patients who develop reduced or dysfunctional EPCs, aimed compare EPC level function experienced vs. matched controls.
Abstract Background The last decade, regarded as the DES era in PCI, has witnessed significant advances management of coronary disease. We aimed to assess temporal trends practice and outcome percutaneous intervention (PCI) during drug eluting stent (DES) era. Methods analyzed 18,641 consecutive PCI's performed between January 2004 December 2016, distinguished by procedural date ( Q 1 : 2004–2006, n = 4,865; 2 2007–2009, 4,977; 3 2010–2012, 4,230; 4 2013–2016, 4,569). Results At...
Accumulated experience combined with technological advancements in percutaneous coronary interventions (PCI) over the past four decades, has led to a gradual increase PCI utilization and complexity. We aimed investigate temporal trends complexity outcomes of complex (C-PCI) our institution.We analyzed 20,301 consecutive procedures performed 12-year period. C-PCI was defined as procedure involving at least one following: Chronic total occlusion (CTO), left main (LM), bifurcation or saphenous...
ABSTRACT Background Although the latest studies failed to prove benefit of routine intra‐aortic balloon pump (IABP) use in patients with acute myocardial infarction (MI) presenting cardiogenic shock, IABP utilization selected cases “real world” practice is unknown. Aims We sought follow temporal trends a real‐world cohort coronary syndrome (ACS). Methods evaluated and patient outcomes from Acute Coronary Syndrome Israel Survey (ACSIS) between years 2000 2021. Temporal at two time periods...
Background: Cardiogenic shock (CS) remains the leading cause of ST elevation myocardial infarction (STEMI)-related mortality. Contemporary studies have shown no sex-related differences in Methods: STEMI-CS patients undergoing primary percutaneous coronary intervention (PPCI) were included based on a dedicated prospective STEMI database. We compared sex-specific CS characteristics at baseline, during hospitalization, and subsequent clinical outcomes. Endpoints all-cause mortality major...
Background Peripheral artery disease (PAD) is a known risk factor for adverse outcomes in patients undergoing percutaneous coronary intervention. However, some studies PAD not an independent factor. We sought to examine the impact of on large prospective intervention registry. Methods and Results From our single‐center registry, we have retrospectively analyzed 25 690 (years 2004–2018). examined influence short‐ long‐term using both regression propensity‐matched analyses. Patients with...
Background: By and large, prior registries randomized trials have not distinguished between acute heart failure (AHF) associated with coronary syndrome (ACS) versus other causes.
Complex aortic atherosclerotic plaques (AAPs) carry a significant risk of embolism. Currently, two-dimensional (2D) transoesophageal echocardiography (TOE) is the principal diagnostic tool AAPs. However, we hypothesized that data obtained from three-dimensional (3D) imaging may improve AAPs' spatial assessment. The study included 67 patients (aged 70 ± 15 years, 35 men), who had routine TEE studies. thoracic aorta was studied arch to distal descending aorta, using x-plane mode (simultaneous...
αMUPA transgenic mice spontaneously consume less food compared with their wild type (WT) ancestors due to endogenously increased levels of the satiety hormone leptin. share many benefits under caloric restriction (CR) including an extended life span. To understand mechanisms linked cardiac aging, we explored response hearts ischemic conditions at age 6, 18, or 24 months. Mice were subjected myocardial infarction (MI) in vivo and ischemia/reperfusion ex vivo. Compared WT mice, showed...
Acute ST elevation myocardial infarction (STEMI) presenting with cardiogenic shock (CS) is associated dismal prognosis. In the last years, significant advances have been made in reperfusion techniques and pharmacological treatment. Therefore, we aimed to assess outcome of these patients during past decade identify major factors that impact their prognosis.We identified 170 who presented STEMI, CS, underwent primary percutaneous coronary intervention (PCI) between 2001 2011. Patients were...
Despite recent progress in coronary artery disease treatment, ST-segment elevation myocardial infarction (STEMI) remains a very high-risk medical condition. Whether patients' outcomes, following implementation of the 2012 European Society Cardiology (ESC) STEMI guidelines have improved, is yet unclear.The study was based on prospective detailed registry 2004 consecutive patients with treated primary percutaneous intervention (pPCI). We compared trends during two different time periods...
Prasugrel is a third-generation thienopyridine, with significant pharmacodynamic and clinical advantages over clopidogrel. There are few data on the effects of prasugrel therapy, as compared clopidogrel, in terms perfusion during percutaneous coronary intervention (PCI), patients ST-elevation myocardial infarction (STEMI).A total 128 STEMI, pretreated 60 mg loading dose (mean age=55.9±9.1; 10.9% were women 18.0% had diabetes), propensity-matched clopidogrel 600 age=58.7±10.7; 10.2% 19.5%...
Objective The transradial approach (TRA) has increasingly been adopted for the use of percutaneous coronary interventions (PCI), with reported clinical benefits. Little is known regarding change in outcomes over time. Patients and methods From our large single-center PCI registry, we have analyzed 15 429 patients two periods – 2008–2012 (period 1) 2013–2017 2). We examined proportions TRA, influence on in-hospital outcomes, adjusted long-term effects. Results rate TRA rose from 15.9% period...