A5084927644- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Peripheral Artery Disease Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Optical Coherence Tomography Applications
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Disease and Adiposity
- Advanced MRI Techniques and Applications
- Cardiac Arrhythmias and Treatments
- Atherosclerosis and Cardiovascular Diseases
- Aortic aneurysm repair treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Structural Anomalies and Repair
- Sarcoidosis and Beryllium Toxicity Research
- Atrial Fibrillation Management and Outcomes
- Heart Failure Treatment and Management
- Cardiovascular Health and Disease Prevention
- Cardiac and Coronary Surgery Techniques
- Pericarditis and Cardiac Tamponade
- Cardiac pacing and defibrillation studies
- Coronary Artery Anomalies
- Cardiovascular Issues in Pregnancy
Wakayama Medical University
2016-2025
Imperial College London
2016-2021
Fukuyama Cardiovascular Hospital
2021
St. Marianna University School of Medicine
2019
Hammersmith Hospital
2018-2019
Chonnam National University Hospital
2019
Gifu Heart Center
2018
Union Hospital
2017
Samsung Medical Center
2017
Jilin University
2017
The study sought to determine the coronary flow characteristics of angiographically intermediate stenoses classified as discordant by fractional reserve (FFR) and instantaneous wave-free ratio (iFR).Discordance between FFR iFR occurs in up 20% cases. No comparisons have been reported FFR/iFR unobstructed vessels.Baseline hyperemic velocity (CFR) were compared across 5 vessel groups: FFR+/iFR+ (108 vessels, n = 91), FFR-/iFR+ (28 24), FFR+/iFR- (22 22), FFR-/iFR- (208 154), an group (201...
The authors sought to evaluate the accuracy of instantaneous wave-Free Ratio (iFR) pullback measurements predict post-percutaneous coronary intervention (PCI) physiological outcomes, and quantify how often iFR alters PCI strategy in real-world clinical settings. In tandem diffuse disease, offline analysis continuous measurement has previously been demonstrated accurately outcome revascularization. However, online approach (iFR pullback) remains untested. Angiographically intermediate and/or...
There are limited data on the clinical implications of total physiologic atherosclerotic burden assessed by invasive studies in patients with coronary artery disease. We investigated prognostic sum fractional flow reserve (FFR) three vessels (3V-FFR). A 1136 underwent FFR measurement (3V FFR-FRIENDS study, NCT01621438). The were classified into high and low 3V-FFR groups according to median value (2.72). primary endpoint was major adverse cardiac events (MACE, a composite death, myocardial...
Abstract Aims The ability of optical coherence tomography (OCT) to detect plaques at high risk developing acute coronary syndrome (ACS) remains unclear. aim this study was evaluate the association between non-culprit characterized as both lipid-rich plaque (LRP) and thin-cap fibroatheroma (TCFA) by OCT subsequent ACS events lesion level. Methods results In 1378 patients who underwent OCT, 3533 were analysed for presence LRP (maximum lipid arc > 180°) TCFA (minimum fibrous cap...
Background: For the identification of functionally significant coronary artery disease, there have not been any dedicated optical coherence tomography (OCT) studies reported previously, although OCT can clearly detect vessel lumina at higher resolution than intravascular ultrasound (IVUS). Methods and Results: fractional flow reserve (FFR) measurements were performed in 62 intermediate lesions 59 patients. FFR was calculated as ratio distal pressure divided by proximal during maximal...
Stent edge restenosis (SER) remains a potential limitation of drug-eluting stents. The aim this study was to determine optical coherence tomography (OCT) predictors for angiographic late SER after everolimus-eluting stent implantation.We retrospectively analyzed 319 patients who underwent OCT immediately implantation and scheduled 9- 12-month follow-up angiography. binary rate 10% (32/319) in the patients, 8.4% (32/382) lesions, 4.4% (33/744) segments. In segments at post stenting,...
Background— 18 F-sodium fluoride ( F-NaF) positron-emission tomography has been introduced as a potential noninvasive imaging tool to identify plaques with high-risk characteristics in patients coronary artery disease. We sought evaluate the clinical relevance of F-NaF uptake using optical coherence (OCT), intravascular ultrasound (IVUS), and computed angiography Methods Results— The target population consisted 51 prospectively enrolled (93 stenoses) who underwent before invasive...
Background: Circulating monocytes can be divided into 2 subsets typically identified by the expression of CD14 and CD16. Although previous studies have shown that circulating contribute to progression coronary atherosclerotic lesions, relationship between severity artery disease (CAD) distinct monocyte has not previously been evaluated. We investigated CAD assessed angiography (CAG) in patients with stable angina pectoris (SAP). Methods Results: enrolled 125 who underwent diagnostic CAG....
Quantitative flow ratio (QFR) is a novel physiological index of the severity coronary stenosis. The aim present study was to investigate relationship between QFR and instantaneous wave-free (iFR).We analyzed contrast-flow QFR, iFR, fractional reserve (FFR) in 100 arteries with intermediate stenosis.There high correlation (r=0.71, P<0.001) good agreement (mean difference: -0.09±0.11) iFR. Both iFR were correlated significantly FFR (r=0.89, P<0.001 r=0.76, P<0.001, respectively). mean absolute...
Background: The safety of fractional flow reserve (FFR)-based deferral revascularization remains to be fully established in real-world practice. We sought assess clinical outcomes after based on FFR. Methods: J-CONFIRM registry (Long-Term Outcomes Japanese Patients With Deferral Coronary Intervention Based Fractional Flow Reserve Multicenter Registry) prospectively enrolled 1263 patients with 1447 lesions whom was deferred FFR at 28 centers. primary study end point the cumulative 2-year...
Background: Little large-scale data is available about the long-term (beyond 3 years) clinical outcomes after fractional flow reserve (FFR)–based deferral of revascularization in practice. We sought to assess 5-year based on FFR. Methods: The J-CONFIRM registry (Long-Term Outcomes Japanese Patients With Deferral Coronary Intervention Based Fractional Flow Reserve Multicenter Registry) prospectively enrolled 1263 patients with 1447 lesions whom was deferred FFR from 28 centers. primary study...
Background: Plaque characteristics associated with effective intravascular lithotripsy (IVL) treatment of calcification have not been investigated. This study identified calcified plaque that favor the use IVL.
BACKGROUND: Limited large-scale, real-world data exist on the prevalence and clinical impact of discordance between fractional flow reserve (FFR) nonhyperemic pressure ratios (NHPRs). METHODS: The J-PRIDE registry (Clinical Outcomes Japanese Patients With Coronary Artery Disease Assessed by Resting Indices Fractional Flow Reserve: A Prospective Multicenter Registry) prospectively enrolled 4304 lesions in 3200 patients from 20 centers. were classified into FFR+/NHPR−, FFR−/NHPR+, FFR+/NHPR+,...