A5035978546- Coronary Interventions and Diagnostics
- Peripheral Artery Disease Management
- Cardiac Imaging and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Valve Diseases and Treatments
- Acute Myocardial Infarction Research
- Vascular Procedures and Complications
- Aortic aneurysm repair treatments
- Venous Thromboembolism Diagnosis and Management
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Arrhythmias and Treatments
- Cardiovascular Function and Risk Factors
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac pacing and defibrillation studies
- Innovation Policy and R&D
- Orthopaedic implants and arthroplasty
- Aortic Thrombus and Embolism
- Advancements in Photolithography Techniques
- Cardiac electrophysiology and arrhythmias
- Coronary Artery Anomalies
- Corporate Finance and Governance
- Optical Coherence Tomography Applications
- Cardiac tumors and thrombi
- Diabetes Treatment and Management
Sapporo Science Center
2023-2025
Kokura Memorial Hospital
2014-2023
The University of Tokyo
2016
Massachusetts General Hospital
2014-2015
Harvard University
2014-2015
Tsukuba Medical Center Hospital
2014
Memorial Hospital of South Bend
2014
Harbin Medical University
2014
University of Occupational and Environmental Health Japan
2012
Fukuoka Hospital
2012
The relationship between major adverse cardiac events (MACE) and serum polyunsaturated fatty acid (PUFA) parameters has not been well documented in patients who have undergone percutaneous coronary intervention (PCI). aim of the present study was to investigate this relationship.A total 284 consecutive underwent elective PCI were enrolled stratified according median levels n-6 PUFAs (arachidonic [AA]), n-3 (eicosapentaenoic [EPA] docosahexaenoic [DHA]), EPA/AA DHA/AA ratios. these PUFA...
Stent fracture (SF) after drug-eluting stent implantation has recently become an important concern because of its potential association with in-stent restenosis and thrombosis. However, the incidence clinical impact SF everolimus-eluting remain unclear.A total 1035 patients 1339 lesions undergoing follow-up angiography 6 to 9 months index procedure were analyzed. was defined as complete or partial separation stent, assessed by plain fluoroscopy intravascular ultrasound during follow-up. We...
Abstract Objectives We sought to evaluate the incidence and clinical impact of calcified nodule (CN) in patients with heavily lesions requiring rotational atherectomy (RA). Background It remains unclear whether CN impacts adversely on outcomes lesions. Methods Between January 2011 February 2014, 264 after second‐generation drug‐eluting stent (DES) implantation following RA were retrospectively enrolled. was defined as a convex shape luminal side calcium assessed by intravascular ultrasound....
Vessel-level physiological data derived from pressure wire measurements are one of the important determinant factors in optimal revascularisation strategy for patients with multivessel disease (MVD). However, these may result complications and a prolonged procedure time.
The mechanism and time course of in-stent restenosis (ISR) after implantation second-generation DES have not yet been fully elucidated. We sought to evaluate the differences in tissue characteristics between different phases ISR using optical coherence tomography (OCT).Methods Results:From June 2010 December 2015, 324 consecutive patients with 337 lesions underwent OCT. Of these, we analyzed 53 who had their first OCT before any procedures. According timing ISR, were divided into early group...
Background: The risk factors and long-term clinical outcomes of patients with definite stent thrombosis (ST) after second-generation drug-eluting (DES) implantation have not yet been adequately assessed. Methods Results: REAL-ST (Retrospective Multicenter Registry ST After First- Second-Generation DES Implantation) included 313 (early ST, n=179; late n=66; very n=68). Four without were identified as control for each case. Risk mostly different according to the timing ST: ST-segment–elevation...
Background: Little large-scale data is available about the long-term (beyond 3 years) clinical outcomes after fractional flow reserve (FFR)–based deferral of revascularization in practice. We sought to assess 5-year based on FFR. Methods: The J-CONFIRM registry (Long-Term Outcomes Japanese Patients With Deferral Coronary Intervention Based Fractional Flow Reserve Multicenter Registry) prospectively enrolled 1263 patients with 1447 lesions whom was deferred FFR from 28 centers. primary study...
BACKGROUND: Limited large-scale, real-world data exist on the prevalence and clinical impact of discordance between fractional flow reserve (FFR) nonhyperemic pressure ratios (NHPRs). METHODS: The J-PRIDE registry (Clinical Outcomes Japanese Patients With Coronary Artery Disease Assessed by Resting Indices Fractional Flow Reserve: A Prospective Multicenter Registry) prospectively enrolled 4304 lesions in 3200 patients from 20 centers. were classified into FFR+/NHPR−, FFR−/NHPR+, FFR+/NHPR+,...
The delivery of the rotational atherectomy burr can sometimes be hindered in distal calcified lesions complicated by proximal vessel tortuosity or other obstacles. This problem may result procedural failure fatal complications, including coronary perforation, entrapment, driveshaft fracture. To prevent these catastrophic outcomes and ensure successful delivery, we introduce DELIVER (Deep Engagement guide catheter 5-F chiLd-guIde for deliVEry subsequent Rotational atherectomy) technique....
ABSTRACT Background Burr fracture during rotational atherectomy (RA) is a rare but potentially devastating complication. Due to its infrequency, comprehensive data on incidence, mechanisms, and management are lacking. This study aimed investigate the contributing factors, strategies for burr fractures RA procedures. Methods retrospective analysis included all patients who underwent PCI with at single center between January 2013 October 2024. Data were collected from prospective registry....
ABSTRACT Percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) lesions with ambiguous proximal cap remains challenging. We present a successful CTO‐PCI case involving ambiguity, treated by combining balloon‐assisted subintimal entry (BASE) and tip‐detection antegrade dissection re‐entry (TD‐ADR) techniques. The BASE‐facilitated TD‐ADR technique is novel approach has the potential to enhance safety efficacy of procedures.
Background Sleep‐disordered breathing ( SDB ) has been recognized as an important risk factor for cardiovascular diseases; however, the impact of on long‐term outcomes in patients with acute coronary syndrome not fully evaluated. Methods and Results We performed overnight cardiorespiratory monitoring 241 who were successfully treated primary percutaneous intervention between January 2005 December 2008. The presence was defined apnea–hypopnea index ≥5 events per hour. end point incidence...
Background: The safety of fractional flow reserve (FFR)-based deferral revascularization remains to be fully established in real-world practice. We sought assess clinical outcomes after based on FFR. Methods: J-CONFIRM registry (Long-Term Outcomes Japanese Patients With Deferral Coronary Intervention Based Fractional Flow Reserve Multicenter Registry) prospectively enrolled 1263 patients with 1447 lesions whom was deferred FFR at 28 centers. primary study end point the cumulative 2-year...
Stent fracture (SF) after drug-eluting stent implantation has become an important concern. The aim of this study was to assess the incidence, predictors, and clinical impact SF biolimus-eluting stent.A total 1026 patients with 1407 lesions undergoing Nobori follow-up angiography within 9 months index procedure were analyzed. defined as complete or partial separation stent, assessed by using plain fluoroscopy, intravascular ultrasound, optical coherence tomography during follow-up. We rate...
Background:Clinical outcomes of implantation the newer-generation drug-eluting stent (DES) following rotational atherectomy for heavily calcified lesions remain unclear in real-world setting.Methods and Results:We enrolled 252 consecutive patients (273 lesions) treated with DES atherectomy. The primary endpoint was cumulative 2-year incidence major adverse cardiovascular events (MACE), defined as cardiac death, myocardial infarction, clinically-driven target lesion revascularization,...
The Ultimaster bioresorbable polymer sirolimus-eluting stent (BP-SES) is a newly developed drug-eluting (DES) that consists of thin-strut, cobalt chromium with coated only albuminally. We sought to compare tissue coverage in coronary lesions treated BP-SES the XIENCE permanent everolimus-eluting (PP-EES) using optical coherence tomography (OCT).A total 36 patients participated CENTURY II trial our institution and were randomly assigned (n = 15) PP-EES 21). Of these, 27 (13 14 PP-EES)...
Post-challenge hyperglycemia (PH) is well-established as one of risk factors for coronary artery disease. However, it remains unclear whether PH affects clinical outcomes in patients with stable angina undergoing percutaneous intervention (PCI). A total 828 PCI were retrospectively analyzed. Of these, 452 previously diagnosed diabetes mellitus (DM) or fasting plasma glucose (PG) ≥126 mg/dl and HbA1c ≥6.5% defined known DM. The remaining 376 divided into the two groups according to 2-h PG:...
The primary objective was to assess the performance of a new generation thin-strut sirolimus-eluting coronary stent with abluminal biodegradable polymer in an all comer population. secondary detail differences contemporary percutaneous intervention (PCI) practice worldwide.