A5067994838- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Cardiac Arrhythmias and Treatments
- Acute Myocardial Infarction Research
- Infective Endocarditis Diagnosis and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Lipoproteins and Cardiovascular Health
- Peripheral Artery Disease Management
- Atrial Fibrillation Management and Outcomes
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Coronary Artery Anomalies
- Aortic Disease and Treatment Approaches
- Atherosclerosis and Cardiovascular Diseases
- Aortic aneurysm repair treatments
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Disease and Adiposity
- Pulmonary Hypertension Research and Treatments
- Venous Thromboembolism Diagnosis and Management
- Cardiac tumors and thrombi
- Aortic Thrombus and Embolism
- Cardiac pacing and defibrillation studies
- Viral Infections and Immunology Research
Kobe University
2015-2024
Kobe University Hospital
2016-2023
Kobe Institute Of Computing
2021
Ministry of Health Labour and Welfare
2020
Hyogo Brain and Heart Center
2011-2018
HeartFlow (United States)
2016
Himeji Medical Center
2012
Abstract Aims Mitral annular disjunction is fibrous separation between the attachment of posterior mitral leaflet and basal left ventricular myocardium initially described in dissected hearts. Currently, it commonly evaluated by echocardiography, potential relationships with valve prolapse arrhythmia have been suggested. However, controversy remains as its prevalence extent not fully elucidated normal living subjects. Methods results Systolic datasets cardiac computed tomography obtained...
Evidence of prognostic factors for stent failure after drug-eluting implantation calcified nodules (CNs) is limited.
BACKGROUND: Limited large-scale, real-world data exist on the prevalence and clinical impact of discordance between fractional flow reserve (FFR) nonhyperemic pressure ratios (NHPRs). METHODS: The J-PRIDE registry (Clinical Outcomes Japanese Patients With Coronary Artery Disease Assessed by Resting Indices Fractional Flow Reserve: A Prospective Multicenter Registry) prospectively enrolled 4304 lesions in 3200 patients from 20 centers. were classified into FFR+/NHPR−, FFR−/NHPR+, FFR+/NHPR+,...
To evaluate the outcome of radiotherapy for recurrent esophageal cancer after surgery and to determine prognostic factors.From 1987 through 2002, 82 patients treated with loco-regional recurrences were retrospectively reviewed. The stage at initial was I in 16, II 41, III or higher 24 unknown 1. median size tumors 3.5 cm diameter. Fifty-two alone, 30 combined chemotherapy. total dose external given 50.4 Gy 28 fractions.The survival period recurrence 7.0 months. 2- 5-year overall rate all 22...
Knowledge of the anatomy membranous septum, as a surrogate to location atrioventricular conduction axis, is prerequisite for those undertaking transcatheter implantation aortic valve (TAVI). Equally important its relationship virtual basal ring. This feature, however, has yet be adequately described in living heart. We analyzed computed tomographic angiographic datasets from 107 candidates (84.1 ± 5.2 years, 68% women) TAVI. Using multiplanar reconstructions, we measured height and width...
Optical coherence tomography–derived fractional flow reserve (OCT-FFR) correlates strongly with wire-based FFR; however, its clinical significance remains uncertain. This study sought to investigate the relationship between post–percutaneous coronary intervention (PCI) OCT-FFR and long-term outcomes in acute syndrome (ACS). retrospective, multicenter, observational cohort included consecutive patients ACS who underwent OCT-guided emergency PCI. We analyzed post-PCI OCT images calculated...
Proprotein convertase subtilisin/kexin type 9 inhibitors stabilize vulnerable plaque, reducing cardiovascular events. However, manual optical coherence tomography (OCT) analysis of drug efficacy is challenging because signal attenuation within lipid plaques.
Background Myocardial extracellular volume fraction (ECV), measured by cardiac magnetic resonance imaging, is a useful prognostic marker for patients who have undergone aortic valve replacement (AVR) stenosis. However, the significance of ECV measurements based on computed tomography (CT) unclear. This study evaluated association between with dual-energy CT and clinical outcomes in stenosis underwent transcatheter or surgical AVR. Methods Results We retrospectively enrolled 95 consecutive...
Abstract This study determined the predictive accuracy of optical frequency domain imaging (OFDI) on debulking effects rotational atherectomy (RA) and compared OFDI catheter-based with Rota wire-based prediction methods. prospective, single-center, observational included 55 consecutive patients who underwent OFDI-guided RA. On pre-RA images, a circle, identical to burr was drawn at center catheter (OFDI method) or wire (wire-based method). The area overlapping vessel wall defined as...
Background It is axiomatic that the diameter of virtual basal ring aortic root, which elliptical rather than circular, will differ when assessed using between bisecting as opposed to off‐center cuts. Such differences, however, pertain directly echocardiographic assessments so‐called valvar annulus, have yet be systematically explored. Methods We retrospectively analyzed 30 patients undergoing coronary computed tomographic angiography, measuring routine multiplanar reconstructions. made...
Even with the use of a reduced energy setting (20-25 W), excessive transmural injury (ETI) following catheter ablation atrial fibrillation (AF) is reported to develop in 10% patients. However, incidence ETI depends on pulmonary vein isolation (PVI) method and its esophageal temperature monitor setting. Data comparing AF without monitoring (ETM) are still lacking.This study was comprised 160 patients (54% paroxysmal, mean: 24.0±2.9 kg/m(2)). Eighty underwent accompanied by ETM. The primary...
The aortic root is wedged within the cardiac base. precise extent of wedging, however, and its influence on surrounding structures, has not been systematically investigated. We analysed 100 consecutive patients, who underwent coronary arterial computed tomographic angiography. assessed wedging by measuring vertical distance between non-adjacent sinus inferior epicardium. A shorter indicates deeper wedging. tilt angle diameter ascending aorta, relative heights left atrial roof oval fossa,...
In-stent neoatherosclerosis (NA) is a risk for future cardiovascular events through atherosclerotic progression in non-stented lesions. Using optical coherence tomography, this study assessed the efficacy of intensive therapy with 10 mg/day rosuvastatin plus 1,800 eicosapentaenoic acid (EPA) vs. standard 2.5 on native coronary plaques patients NA.
Abstract Background The radiofrequency (RF) lesions for atrial fibrillation (AF) ablation can be visualized by delayed enhancement magnetic resonance imaging (DE‐MRI). However, the quality of anatomical information provided DE‐MRI is not adequate due to its spatial resolution. In contrast, angiography (MRA) provides similar regarding left atrium (LA) and pulmonary veins (PVs) as computed tomography angiography. We hypothesized that fused with MRA will compensate inadequate image DE‐MRI....
We aimed to assess the effect of 10 mg/day rosuvastatin plus eicosapentaenoic acid (EPA) versus 2.5 on extent neoatherosclerosis using optical coherence tomography (OCT).We randomly assigned 50 patients with non-obstructive neoatherosclerotic plaques detected OCT receive either and EPA 1,800 (intensive therapy group) or mg (standard group). Follow-up was performed one year later evaluate serial changes in neoatherosclerosis. The serum low-density lipoprotein cholesterol (LDL-C) level...
Background We evaluated the importance of high-density lipoprotein (HDL) functionality for target-lesion revascularization in patients treated with coronary stents using a rapid cell-free assay system to evaluate functional capacity HDL accept additional cholesterol (cholesterol-uptake capacity; CUC). Methods and Results From an optical coherence tomography (OCT) registry stents, 207 were enrolled their was functionally by measuring CUC. Follow-up OCT performed (median duration, 24.5 months...
Aims: The aim of this study was to evaluate the accuracy minimum lumen area (MLA) by coronary computed tomography angiography (cCTA) and its impact on fractional flow reserve (FFRCT).Methods results: Fifty-seven patients (118 lesions, 72 vessels) who underwent cCTA optical coherence (OCT) were enrolled. OCT co-registered MLAs measured with both modalities. FFROCT calculated using OCT-updated models cCTA-based geometry replaced OCT-derived geometry. Lesions grouped Agatston score (AS)...
Perivascular inflammation contributes to the development of atherosclerosis and microcirculatory dysfunction. Pericoronary adipose tissue (PCAT) attenuation, measured by coronary computed tomography angiography, is a potential indicator inflammation. However, relationship between PCAT dysfunction, periprocedural myocardial injury (PMI) remains unclear.
Combining morphological and physiological evaluations might improve the risk stratification of patients who undergo percutaneous coronary intervention (PCI) for acute syndrome (ACS) culprit lesions.
Abstract Aims Optical coherence tomography (OCT) can identify high-risk plaques indicative of worsening prognosis in patients with acute coronary syndrome (ACS). However, manual OCT analysis has several limitations. In this study, we aim to construct a deep-learning model capable automatically predicting ACS from patient images following percutaneous intervention (PCI). Methods and results Post-PCI 418 were input into comprising convolutional neural network (CNN) transformer. The primary...