A5074055617- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Peripheral Artery Disease Management
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Atrial Fibrillation Management and Outcomes
- Optical Coherence Tomography Applications
- Infective Endocarditis Diagnosis and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Vascular Procedures and Complications
- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Cardiovascular Disease and Adiposity
- Acute Myocardial Infarction Research
- Venous Thromboembolism Diagnosis and Management
- Frailty in Older Adults
- Fatty Acid Research and Health
- Diagnosis and Treatment of Venous Diseases
- Vascular anomalies and interventions
- Cardiac, Anesthesia and Surgical Outcomes
- Viral Infections and Immunology Research
- IL-33, ST2, and ILC Pathways
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Nutrition and Health in Aging
CVPath Institute
2024-2025
Kobe University
2021-2024
Himeji Medical Center
2023
Hyogo Brain and Heart Center
2020-2021
Hyogo Prefectural Awaji Medical Center
2019-2020
Evidence of prognostic factors for stent failure after drug-eluting implantation calcified nodules (CNs) is limited.
Combining morphological and physiological evaluations might improve the risk stratification of patients who undergo percutaneous coronary intervention (PCI) for acute syndrome (ACS) culprit lesions.
Proprotein convertase subtilisin/kexin type 9 inhibitors stabilize vulnerable plaque, reducing cardiovascular events. However, manual optical coherence tomography (OCT) analysis of drug efficacy is challenging because signal attenuation within lipid plaques.
Abstract This study determined the predictive accuracy of optical frequency domain imaging (OFDI) on debulking effects rotational atherectomy (RA) and compared OFDI catheter-based with Rota wire-based prediction methods. prospective, single-center, observational included 55 consecutive patients who underwent OFDI-guided RA. On pre-RA images, a circle, identical to burr was drawn at center catheter (OFDI method) or wire (wire-based method). The area overlapping vessel wall defined as...
Atrial fibrillation (AF) is strongly associated with strokes, heart failure, and increased mortality. This study aims to identify the monocyte–macrophage heterogeneity interactions of these cells non-immune cells, functional biomarkers in patients AF. Therefore, we assess single cell landscape left atria (LA), using a combination nucleus RNA-seq. Myeloid LA tissue are categorized into five macrophage clusters, three monocyte others. Cell-Chat analysis revealed that monocytes IL1B+...
With the rapidly increasing ageing population, heart failure is an urgent challenge, particularly in developed countries. The study aimed to investigate main aetiologies of chronic a super-aged society.The KUNIUMI registry cohort community-based, prospective, observational Awaji Island, Japan. Inhabitants this island aged ≥65 years accounted for 36.3% population. In present study, data from patients with symptomatic were extracted registry. A total 1646 enrolled March 2019 2021, accounting...
Perivascular inflammation contributes to the development of atherosclerosis and microcirculatory dysfunction. Pericoronary adipose tissue (PCAT) attenuation, measured by coronary computed tomography angiography, is a potential indicator inflammation. However, relationship between PCAT dysfunction, periprocedural myocardial injury (PMI) remains unclear.
Acute coronary syndrome (ACS) involves plaque-related thrombosis, causing primary ischemic cardiomyopathy or lethal arrhythmia. We previously demonstrated a unique immune landscape of myeloid cells in the culprit plaques ACS by using single-cell RNA sequencing. Here, we aimed to characterize T level, assess clonal expansion cells, and find therapeutic target prevent ACS.
Abstract Aims Optical coherence tomography (OCT) can identify high-risk plaques indicative of worsening prognosis in patients with acute coronary syndrome (ACS). However, manual OCT analysis has several limitations. In this study, we aim to construct a deep-learning model capable automatically predicting ACS from patient images following percutaneous intervention (PCI). Methods and results Post-PCI 418 were input into comprising convolutional neural network (CNN) transformer. The primary...
Background: Fractional flow reserve-computed tomography (FFRCT) has not been validated in patients with severe aortic stenosis (AS) undergoing transcatheter valve replacement (TAVR) for coronary artery disease due to theoretical difficulties using nitroglycerin such patients.
Background:The clinical frailty scale (CFS) predicts late mortality in patients undergoing transcatheter aortic valve replacement. We evaluated the CFS and other parameters associated with 1-year after balloon valvuloplasty (BAV).
Although cardiac involvement is relatively common in mixed connective tissue disease (MCTD), few reports on MCTD-associated fulminant myocarditis are available.A 22-year-old woman diagnosed with MCTD was admitted to our institution for cold-like symptoms and chest pain. Echocardiography revealed that the left ventricular ejection fraction (LVEF) had rapidly decreased from 50 20%. Because endomyocardial biopsy no significant lymphocytic infiltration, immunosuppressant drugs were not started...
Abstract Background Balloon aortic valvuloplasty (BAV) offers an alternative to conventional valve replacement in elderly and frail patients with severe stenosis (AS) for whom there are no other effective options. We aimed investigate the mid-term effect of BAV on mitral regurgitation (MR) AS. Methods Our analysis was based data from 83 AS (mean age, 86 ± 5 years; female, 68) treated using BAV. Echocardiography performed before procedure at 1 3 months after. MR quantified by measuring jet...
Objective Previous studies have described several prognostic factors for heart failure (HF); however, these results were derived from registries consisting of conventional age groups, which might not represent the increasingly aging society. The present study explored all-cause death in hospitalized patients with HF across different categories using an acute registry that included relatively old patients. Methods From a total 1,971 consecutive HF, 1,136 enrolled. We divided into 4 groups...