- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Lipoproteins and Cardiovascular Health
- Cerebrovascular and Carotid Artery Diseases
- Aortic aneurysm repair treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Protease and Inhibitor Mechanisms
- Peripheral Artery Disease Management
- Atherosclerosis and Cardiovascular Diseases
- Cardiac Valve Diseases and Treatments
- Cardiac Arrhythmias and Treatments
- Cardiac tumors and thrombi
- Vascular Procedures and Complications
- Cardiac electrophysiology and arrhythmias
- Peptidase Inhibition and Analysis
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Syncope and Autonomic Disorders
- Pulmonary Hypertension Research and Treatments
- Cell Adhesion Molecules Research
- Public Administration and Political Analysis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pericarditis and Cardiac Tamponade
- Healthcare cost, quality, practices
- Aortic Thrombus and Embolism
Kobe University
2013-2025
Cardiovascular Research Foundation
2023-2025
Columbia University Irving Medical Center
2024-2025
St. Francis Hospital
2024-2025
New York Hospital Queens
2023-2025
NewYork–Presbyterian Hospital
2023-2025
St. Francis Hospital
2025
Columbia University
2023-2024
Nippon Medical School Hospital
2021
Ministry of Health Labour and Welfare
2020
Pericoronary adipose tissue (PCAT) attenuation, measured using coronary computed tomography angiography (cCTA), is a potential marker of inflammation. We aimed to examine the association between inflammation, as assessed by measuring PCAT attenuation before percutaneous intervention (PCI), and clinical outcomes PCI current-generation drug-eluting stents (DES). retrospectively studied consecutive patients who underwent cCTA with DES. Adverse plaque characteristics, calcified (CP) burden,...
Background The prognostic impact of optical coherence tomography-diagnosed culprit lesion morphology in acute coronary syndrome (ACS) has not been systematically examined real-world settings. Methods and Results This investigator-initiated, prospective, multicenter, observational study was conducted at 22 Japanese hospitals to identify the prevalence underlying ACS causes (plaque rupture [PR], plaque erosion [PE], calcified nodules [CN]) their on clinical outcomes. Patients with diagnosed...
Accurate intravascular ultrasound (IVUS) measurements are important in IVUS-guided percutaneous coronary intervention optimization by choosing the appropriate device size and confirming stent expansion. The purpose of this study was to assess accuracy machine learning (ML) automatic segmentation artery vessel lumen dimensions balloon sizing. Using expert analysis as gold standard, ML 60 MHz IVUS images developed using 8,076 cross-sectional from 234 patients, which were randomly split into...
Proprotein convertase subtilisin/kexin type 9 inhibitors stabilize vulnerable plaque, reducing cardiovascular events. However, manual optical coherence tomography (OCT) analysis of drug efficacy is challenging because signal attenuation within lipid plaques.
Objective The coronavirus disease 2019 (COVID-19) pandemic has had a significant impact on global healthcare systems. Some studies have reported the negative of COVID-19 ST-elevation myocardial infarction (STEMI) patients; however, in Japan remains unclear. This study investigated STEMI patients admitted to an academic tertiary-care center Tokyo, Japan. Methods In this retrospective, observational, cohort study, we included 398 consecutive who were our institute from January 1, 2018, March...
BACKGROUND: Coronary stenting alters vessel dynamics, displacing hinge movement closer to stent edges. We aimed investigate whether calcified nodules (CNs) are more frequent at edges associated with calcium. METHODS: In vessels previously implanted stents evaluated by optical coherence tomography, 4 different lesions were studied: stent-edge or without a CN, and unstented native CN. RESULTS: 801 patients, 989 354 identified. Stent-edge exhibited higher prevalence of CNs versus (15.7% 5.1%; P...
Even after successful revascularization with primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI), subsequent adverse events still occur. Previous studies have suggested potential benefits of intravascular imaging, including optical coherence tomography (OCT). However, the feasibility OCT-guided PCI has not been systematically examined in these patients. The ATLAS-OCT (ST-elevation Acute infarcTion and cLinicAl outcomeS treated by Optical...
Background We evaluated the importance of high-density lipoprotein (HDL) functionality for target-lesion revascularization in patients treated with coronary stents using a rapid cell-free assay system to evaluate functional capacity HDL accept additional cholesterol (cholesterol-uptake capacity; CUC). Methods and Results From an optical coherence tomography (OCT) registry stents, 207 were enrolled their was functionally by measuring CUC. Follow-up OCT performed (median duration, 24.5 months...
In-stent neoatherosclerosis (NA) is a risk for future cardiovascular events through atherosclerotic progression in non-stented lesions. Using optical coherence tomography, this study assessed the efficacy of intensive therapy with 10 mg/day rosuvastatin plus 1,800 eicosapentaenoic acid (EPA) vs. standard 2.5 on native coronary plaques patients NA.
A 65-year-old man was referred to our hospital due an acute onset of dyspnea and persistent fever. Echocardiography revealed ejection fraction (EF) 25% with diffuse severe left ventricular (LV) dysfunction. 18F-fluorodeoxy glucose-positron emission tomography imaging showed significantly increased uptake by the LV right walls, indicating active inflammation. The histologic findings endomyocardial biopsy specimens indicated presence epithelioid cell granuloma. final diagnosis thus cardiac...
Background:The effect of intraindividual variability in lipid levels on the onset acute coronary syndrome (ACS) remains uncertain. We evaluated relationship between and culprit lesion morphologies by optical coherence tomography (OCT).
Calcified nodules (CNs) are an increasingly important, high-risk lesion subset.