Norihiko Obata

ORCID: 0000-0003-1158-3152
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About
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Research Areas
  • Cardiac, Anesthesia and Surgical Outcomes
  • Anesthesia and Pain Management
  • Intensive Care Unit Cognitive Disorders
  • Anesthesia and Sedative Agents
  • Anesthesia and Neurotoxicity Research
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Pain Mechanisms and Treatments
  • Pain Management and Opioid Use
  • Functional Brain Connectivity Studies
  • Cardiac Valve Diseases and Treatments
  • Mechanical Circulatory Support Devices
  • Nerve injury and regeneration
  • Aortic Disease and Treatment Approaches
  • Cancer, Stress, Anesthesia, and Immune Response
  • Aortic aneurysm repair treatments
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Atomic and Subatomic Physics Research
  • Airway Management and Intubation Techniques
  • Electroconvulsive Therapy Studies
  • Acute Kidney Injury Research
  • Diabetes Management and Research
  • Pediatric Pain Management Techniques
  • Advanced MRI Techniques and Applications
  • Boron Compounds in Chemistry
  • Epilepsy research and treatment

Kobe University
2018-2025

Kobe University Hospital
2015-2025

Ritsumeikan University
2024

Kobe Children's Hospital
2024

Himeji Medical Center
2023

Creative Research Enterprises (United States)
2018

Okayama University
2010-2014

General anesthesia for patients with poor pulmonary function is a risk factor perioperative complications, and it should be avoided as much possible, depending on the specifics of each case. Herein, anesthetic management partial mastectomy in patient using intertransverse process block (ITPB) reported. A woman her 80s (height 149 cm, weight 45.9 kg) was scheduled to undergo right breast cancer. She had bronchiectasis interstitial pneumonia. ITPB performed, intravenous dexmedetomidine...

10.7759/cureus.78110 article EN Cureus 2025-01-28

Abstract Background Although 5-aminolevulinic acid is useful for the photodynamic diagnosis of bladder tumors, it often causes severe intraoperative hypotension. We report a case postoperative cardiac arrest in addition to hypotension, probably owing use acid. Case presentation An 81-year-old Japanese man was scheduled undergo transurethral resection tumor. The patient took orally 2 hours before entering operating room. After induction anesthesia, his blood pressure decreased 47/33 mmHg....

10.1186/s13256-024-04589-x article EN cc-by Journal of Medical Case Reports 2024-05-30

Under general anesthesia, lidocaine shortens the onset time of vecuronium but it does not affect that rocuronium. We suspected dose rocuronium used in previous reports, 0.6 mg/kg, was too high to detect any difference due lidocaine's effect. investigated effects 1.5 mg/kg on time, 50% depression 100% and duration action 0.4 Sixty adult patients who underwent elective operation under anesthesia without tracheal intubation were randomly divided into two groups: including a group (LG) placebo...

10.24546/0100493127 article EN PubMed 2025-02-12

Abstract: Metastatic bone cancer causes severe pain, but current treatments often provide insufficient pain relief. One of the reasons is that mechanisms underlying are not solved completely. Our previous studies have shown brain-derived neurotrophic factor (BDNF), known as a member family, an important molecule in pathological state some models. We hypothesized expression changes BDNF may be one factors related to pain; this study, we investigated dorsal root ganglia rat model. As expected,...

10.2147/jpr.s63527 article EN cc-by-nc Journal of Pain Research 2014-07-01

Abstract Ketamine has been used to treat chronic pain; however, it is still unknown as what types of pain ketamine effective against. To identify the effect administration subanesthetic-dose in patients with and clarify mechanism effect, we retrospectively investigated brain functional connectivity using resting-state magnetic resonance imaging (rs-fMRI). Patients were divided into responders (Group R: ≥50% improvement on Numerical Rating Scale) non-responders NR). We compared differences...

10.1038/s41598-019-49360-1 article EN cc-by Scientific Reports 2019-09-09

Abstract Background Various factors can cause vascular endothelial damage during cardiovascular surgery (CVS) with cardiopulmonary bypass (CPB), which has been suggested to be associated postoperative complications. However, few studies have specifically investigated the relationship between degree of and acute kidney injury (pAKI). The objectives this study were measure perioperative serum syndecan-1 concentrations in patients who underwent CVS CPB, evaluate their trends, determine...

10.1186/s12871-024-02546-1 article EN cc-by BMC Anesthesiology 2024-04-22

AIMTo investigate the anesthetic management of peroral endoscopic myotomy (POEM) and its associated complications. METHODSThis study was a single-center, retrospective, observational comprising case series all patients who underwent POEM in our hospital from April 2015 to November 2016.We collected data regarding patient characteristics, methods, surgical factors, complications using an electronic chart. RESULTSThere were 86 during period.Preoperatively, maintained on low residue diet for 48...

10.4253/wjge.v10.i9.193 article EN cc-by-nc World Journal of Gastrointestinal Endoscopy 2018-09-16

Abstract Background An aorto-caval fistula is a rare but critical complication of abdominal aortic aneurysm (AAA) rupture, leading to high-output heart failure and increased venous pressure. The anesthetic management such cases, particularly when complicated by an intraoperative right-to-left shunt, seldom reported. Case presentation A 71-year-old man with history atrial fibrillation catheter ablation presented pain, cardiac arrest. Imaging revealed AAA rupture into the inferior vena cava....

10.1186/s40981-024-00735-y article EN cc-by JA Clinical Reports 2024-08-15

There has been much discussion recently about the occurrence of neuropsychological complications during perioperative period. Diabetes is known to be one metabolic risk factors. Although number patients with diabetes mellitus (DM) increasing, pathophysiology postoperative dysfunction in DM still unclear. Recently, a deficiency neurotransmitters, such as monoamines, was reported associated mental disorders. Therefore, we investigated effects surgical stress on behavioral activity and...

10.1186/s12868-020-0556-y article EN cc-by BMC Neuroscience 2020-02-17

Abstract Background The risk of surgical site infection has been reported to be higher in patients with poorly controlled diabetes. Since chronic hyperglycemia impairs neutrophil functions, preoperative glycemic control may restore function. However, long-term insulin therapy lead a delay surgery, which problem, especially cancer surgery. It is therefore unfortunate that there have few studies the optimal duration perioperative for diabetes was investigated. Therefore, we investigated...

10.1186/s12902-020-00629-x article EN cc-by BMC Endocrine Disorders 2020-09-29
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