- Pulmonary Hypertension Research and Treatments
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Cardiac Arrhythmias and Treatments
- Venous Thromboembolism Diagnosis and Management
- Advanced X-ray and CT Imaging
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Effects of Exercise
- Lipoproteins and Cardiovascular Health
- IgG4-Related and Inflammatory Diseases
- Cardiac tumors and thrombi
- Eosinophilic Disorders and Syndromes
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Nuclear Physics and Applications
- Cardiac Structural Anomalies and Repair
- Free Radicals and Antioxidants
- Pediatric health and respiratory diseases
- Eosinophilic Esophagitis
- Ultrasound and Hyperthermia Applications
- Atherosclerosis and Cardiovascular Diseases
- Phonocardiography and Auscultation Techniques
- Smoking Behavior and Cessation
- Oral health in cancer treatment
- Vitamin C and Antioxidants Research
Kobe University
2020-2023
Sysmex (Japan)
2016-2023
Kobe University Hospital
2020
Kyoto University
2005
Job Performance Systems (United States)
2002
Tohoku Medical and Pharmaceutical University
1992-1999
Kyoto University Hospital
1983
Takeda (Japan)
1983
Abstract Aims Mitral annular disjunction is fibrous separation between the attachment of posterior mitral leaflet and basal left ventricular myocardium initially described in dissected hearts. Currently, it commonly evaluated by echocardiography, potential relationships with valve prolapse arrhythmia have been suggested. However, controversy remains as its prevalence extent not fully elucidated normal living subjects. Methods results Systolic datasets cardiac computed tomography obtained...
Background Myocardial extracellular volume fraction (ECV), measured by cardiac magnetic resonance imaging, is a useful prognostic marker for patients who have undergone aortic valve replacement (AVR) stenosis. However, the significance of ECV measurements based on computed tomography (CT) unclear. This study evaluated association between with dual-energy CT and clinical outcomes in stenosis underwent transcatheter or surgical AVR. Methods Results We retrospectively enrolled 95 consecutive...
Sequential 12 lead electrocardiograms were recorded during angina pectoris induced by ergonovine maleate in 38 patients with variant angina. Transient U wave inversion was observed 17 ST segment elevation anterior chest leads, but only three of 21 the inferior leads associated right coronary artery spasm. In 17, all whom had spasm left descending artery, sensitivity V5 41%, and that 71%. without occurred attacks 35% patients. During recovery phase, 82% V4 65% V5, though absent both V5. Thus,...
The plasma status of vitamin E has been suggested to be linked the activity coronary artery spasm. This study was designed determine whether is actually consumed in circulation patients with active variant angina having repetitive spasm-induced transient myocardial ischemia and reperfusion.Blood samples were obtained simultaneously from aortic root, sinus right atrium 12 due spasm left artery, nine stable effort control subjects. Plasma (alpha- gamma-tocopherol) concentrations determined by...
Dyslipidemia in patients with coronary vasospasm may be characterized by low level of high-density lipoprotein (HDL)-cholesterol as well apolipoprotein (apo) A-I but not high low-density lipoprotein-cholesterol. This study sought to examine the HDL particle size variant angina.The was examined analyzing serum lipid levels 38 angina compare those 40 control subjects and 30 normocholesterolemic stable effort angina. Also, actual distribution assessed electrophoresis.The HDL-cholesterol, apoA-I...
Background Balloon pulmonary angioplasty (BPA) is a promising treatment modality for nonoperable chronic thromboembolic hypertension (CTEPH). However, BPA atypical CTEPH with concurrent obstructive disease (COPD) remains controversial owing to the risk of exacerbation ventilation‐perfusion mismatch. We aimed evaluate efficacy and safety moderate or severe COPD. Methods Results Data from 149 patients CTEPH, who underwent March 2011 June 2021, were retrospectively analyzed. Patients divided...
We report the cases of two patients with life-threatening acute pulmonary embolism (PE) on chronic thromboembolic hypertension (CTEPH) who were treated rescue balloon angioplasty (BPA). These highlight effect BPA PE CTEPH, which requires veno-arterial extracorporeal membrane oxygenation.
Objective -To examine the association between smoking status of attending physicians and that their patients. Setting - Cardiology division Toyama Medical Pharmaceutical University Hospital two affiliated hospitals in District, Japan. Subjects -A total 259 patients with known ischaemic heart disease who con sulted our outpatient clinic September 1992, at (n = 17). Thirty eight cared for 100 these during a previous admission were also cluded study. Design main outcome measures Smoking was...
A 53-year-old woman was admitted to another hospital because of a 2-month history repeated chest pain and breathlessness. Laboratory examinations demonstrated the presence hypereosinophilia (absolute count 6,500/μL). An endomyocardial biopsy confirmed eosinophilic infiltration with myocardial destruction. On cardiac magnetic resonance imaging, late gadolinium enhancement clearly observed along visceral pericardium as well on endocardial layer. Based multimodal imaging histopathological...
A 28-year-old Japanese woman complained of right chest pain, fever, and cough. Chest radiography revealed consolidation in her lower lobe with a pleural effusion. She was diagnosed pneumonia treated antibiotics, but condition did not improve. referred to our hospital for evaluation. Contrast-enhanced computed tomography (CT) demonstrated large saddle filling defect extending into the pulmonary artery as well proximal branch.
Background: Poor subpleural perfusion (PSP) on dual-energy computed tomography (DE-CT) suggests microvasculopathy in chronic thromboembolic pulmonary hypertension (CTEPH). However, whether the findings are equivalent to those arterial (PAH) remains unclear. The aim of this study was elucidate characteristics CTEPH compared that PAH. Methods: We retrospectively reviewed DE-CT and hemodynamics 23 patients with PAH 113 inoperable CTEPH. Subpleural classified as poor (subpleural spaces all...
BackgroundThe impact of the extent aortic atheroma on patients' prognosis after transcatheter valve replacement (TAVR) has not been completely evaluated. This study aimed to evaluate prognostic value volume (AAV) derived from computed tomography, and effect its differences among segments aorta, in patients undergoing TAVR.MethodsIn total, 143 with symptomatic severe stenosis who underwent pre-procedural tomography before TAVR procedure indication were AAV was calculated by measuring lumen...
Abstract Background High-density lipoprotein (HDL) function has earned an attention as a way of assessing the risk cardiovascular disease. Conventionally, cholesterol efflux capacity (CEC) been used to measure HDL, but because its time-consuming and complex procedure it withheld from being widely in clinical fields. We have previously introduced immunoassay-based technique that measures uptake (CUC) novel HDL functionality. There we demonstrated CUC is capable stratification patients with...
Abstract Background Pulmonary endarterectomy is known to improve hemodynamics in the early postoperative period on chronic thromboembolic pulmonary hypertension (CTEPH). However, there are no reports of hemodynamic changes after balloon angioplasty (BPA) for CTEPH. Purpose The aim this study was clarify BPA. Furthermore, we investigated whether were related phase final Methods We retrospectively enrolled 43 consecutive CTEPH patients placed Swan-Ganz catheter monitoring at first Hemodynamics...
BACKGROUND:Intracardiac repair of tetralogy Fallot (TOF) is generally performed during childhood. However, the majority patients develop sequelae long after surgical repair, which results in significant right ventricular (RV) dilation, RV myocardial dysfunction, and, ultimately, right-sided heart failure. CASE REPORT:A 52-year-old man was referred to our institution for evaluation sudden-onset tachycardia. His medical history included outflow tract reconstruction at 5 years age. Auscultation...
<b>Background:</b> It has been reported that the efficacy of balloon pulmonary angioplasty (BPA) for patients with non-operable chronic thromboembolic hypertension (CTEPH) would be promising. However, some have shown poor response in oxygenation and lung function parameter even after hemodynamics improved. The aim our study was to investigate BPA. <b>Method:</b> Consecutive 103 who underwent BPA from September 2011 August 2018 were enrolled. We evaluated right heart catheterization,...
Abstract Background The existence of microvasculopathy in chronic thromboembolic pulmonary hypertension (CTEPH) had been suggested. However, the impact for pathophysiology unknown. Recently dual-energy computed tomography (DECT) can produce a sensitive iodine distribution map lung fields to quantify perfusion, which may indicate according poor subpleural perfusion. This study aimed examine therapeutic efficacy interventional treatment (pulmonary endarterectomy or/and balloon angioplasty)...