- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Mechanical Circulatory Support Devices
- Bacterial Infections and Vaccines
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Asthma and respiratory diseases
- Infectious Aortic and Vascular Conditions
- Pneumonia and Respiratory Infections
- Aquaculture Nutrition and Growth
- Cardiac Valve Diseases and Treatments
- Cardiac Ischemia and Reperfusion
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac and Coronary Surgery Techniques
- Peripheral Artery Disease Management
- Monoclonal and Polyclonal Antibodies Research
- Renal and Vascular Pathologies
- Pediatric health and respiratory diseases
- Dysphagia Assessment and Management
- Respiratory and Cough-Related Research
- Congenital Heart Disease Studies
- Esophageal and GI Pathology
- SARS-CoV-2 and COVID-19 Research
- Transplantation: Methods and Outcomes
- Marine and environmental studies
Kobe University
2007-2024
National Hospital for Neurology and Neurosurgery
2012-2021
Fukuoka Hospital
2009-2021
University College London
2012-2021
Fukuoka Jo Gakuin Nursing University
2018-2019
Shinshu University
2015-2016
Fukuoka Dental College
2014-2015
Hiroshima University
1981-2009
Chiba University
2008
Osaka University
2007
Background: Nationwide surveillance was conducted in Japan to clarify the status of pediatric invasive pneumococcal diseases (IPD) after introducing a 13-valent conjugate vaccine (PCV13).Methods: Detailed clinical and epidemiologic information IPD cases children aged <15 years were collected from 10 47 prefectures January 2014 December 2022. Streptococcus pneumoniae strains isolated sterile body sites analyzed, including capsular serotypes, multi-locus sequence typing (MLST), antimicrobial...
Background Myocardial extracellular volume fraction (ECV), measured by cardiac magnetic resonance imaging, is a useful prognostic marker for patients who have undergone aortic valve replacement (AVR) stenosis. However, the significance of ECV measurements based on computed tomography (CT) unclear. This study evaluated association between with dual-energy CT and clinical outcomes in stenosis underwent transcatheter or surgical AVR. Methods Results We retrospectively enrolled 95 consecutive...
Total arch replacement necessitating deep hypothermia with circulatory arrest has a greater effect on pulmonary function than other cardiac surgery using cardiopulmonary bypass (CPB). Since April 2004, 100mg of sivelestat sodium hydrate was administrated by bolus injection into pulp circuit at the initiation CPB in every case performed total replacement. We investigated hypothesis that prophylactic use drug attenuates post-pump dysfunction.A retrospective analysis 120 consecutive patients...
Technical details of our strategy for reconstructing the thoracoabdominal aorta are presented. Between October 1999 and June 2012, 152 patients underwent surgery aortic aneurysms (Crawford classification type I =21, II =43, III =73, IV =15). Mean age was 64.6±13.9 years. Sixty-three (41.4%) had dissection, including acute B dissection in 2 (1.2%) ruptured 17 (11.2%). Eight (5.3%) mycotic aneurysms, 3 (2.0%) aortitis. Emergent or urgent performed 25 (16.4%) patients. Preoperative computed...
Hatchery-reared juvenile black sea bream Acanthopagrus schlegeli (Bleeker) are characterized by high lipid storage and low levels of highly unsaturated fatty acids in their bodies. In the present study, we assessed effects dietary fortification diet with eicosapentaenoic acid (EPA) docosahexaenoic (DHA) on improvement physiological activity. Black 50 days old an average weight 0.02 g were reared for either a control (commercial diet) or commercial fortified 3% EPA DHA. The DHA reduced...
Background. Helicobacter pylori is the causative agent of type B chronic gastritis, and plays a major role in pathogenesis gastroduodenal ulcer gastric cancer. Because cancer has been leading cause mortality Japan Korea, we conducted seroepidemiological study to estimate prevalence H. infection Korea order explain current change incidences between two countries. Materials Methods. Samples used for this included 1204 sera from Chinju, 580 Fukuoka, Japan. Immunoblotting, using sonicated crude...
Infective endocarditis is a life threatening disease with high mortality and morbidity, including brain infarction concomitant intracranial hemorrhage. Generally, patients recent hemorrhage are believed to be contraindication undergo cardiac surgery cardiopulmonary bypass. However, some infective occasionally require an unavoidable emergent because of uncontrollable heart failure or on-going thromboembolism even if complicated by In this study, bypass strategy using nafamostat mesilate as...
The objectives of this study were to develop a population pharmacokinetic model and determine the covariates affecting pharmacokinetics busulfan in Japanese pediatric patients who received high-dose oral as conditioning regimen before hematopoietic stem cell transplantation. Population analysis was performed using retrospective therapeutic drug monitoring data (including test dose data) from 103 children. Their ages ranged 2 months 11 years old (mean age, 30 months; median 18 months). plasma...
The goal of this study was to evaluate the fate downstream aorta following total arch replacement.Between October 1999 and March 2018, a 740 patients underwent replacement. After excluding connective tissue disease, previous descending or thoracoabdominal aortic surgery, without adequate preoperative images operative mortality, late outcomes consisting additional surgery for distal dilation events were evaluated in 623 survivors (240 dissections, including 139 with acute dissection 383...
BACKGROUND: This study aimed to investigate the effects of surgical methods on pain duration and oral analgesic administration in patients who underwent cardiac surgery using various minimally invasive methods.METHODS: We included 90 an anterior incision with costal cartilage transection, lateral without or total endoscopic a no retractor. Oral analgesics were postoperatively administered upon patient request. All instructed rate their during daytime 3 7 days postoperatively.RESULTS:...
Left ventricular (LV) free wall rupture particularly in blow-out type is still one of the fatal complications after myocardial infarction. Seven patients had LV following acute was divided into two categories: (true rupture) 5 cases, or oozing (incipient 2 cases. All were deep shock condition and underwent surgery on emergency basis. Patch glue (fibrin glue) technique applied for patients, while direct closure using buttress sutures with additional sutured patch (including GRF patients....
Postextubation dysphagia (PED) is a serious postoperative complication following cardiovascular surgery that can lead to worse prognosis. On the other hand, frailty prognostic factor in patients who undergo cardiac surgery.This study investigated effect of status on PED and impact complications.This single-center retrospective cohort included 644 consecutive underwent elective between May 1, 2014, December 31, 2020; they were assigned or non-PED group based swallowing status, complications...
Background: Young infants with influenza virus infection are frequently hospitalized, and at risk of serious complications including death. With the emergence pandemic A/H1N1 2009, oseltamivir was approved for use in Europe USA, aged < 3 months. However, few data available regarding safety treatment Methods: The clinical from Japanese months laboratory-confirmed infections, who were treated between October 2009 April 2011, collected analyzed. Results: Forty-four included study. median age 1...
Japanese encephalitis (JE) is the leading cause of viral with high mortality and morbidity in Asia. In Japan, however, active recommendation JE vaccine was retracted 2005 because potential risk acute disseminated encephalomyelitis. We aimed to determine recent incidence childhood-onset after domestic change vaccination policy analyze clinical features affected children. A retrospective nationwide survey conducted for pediatric patients Japan from 1995 2015. The national surveillance system...
Abstract Aims Post-extubation dysphagia (PED), an often overlooked problem, is a common and serious complication associated with mortality major morbidity after cardiovascular surgery. Dysphagia considered age-related disease, evaluating its long-term effects pressing issue rapidly progressing ageing worldwide. Therefore, we examined the effect of PED on functional status events in patients undergoing Methods results This single-centre, retrospective cohort study included 712 who underwent...
BackgroundPoor oral health status can lead to a deteriorated level of general and is common among patients undergoing cardiovascular surgery. However, the effect on postoperative outcomes in surgery remains unclear. Thus, we investigated preoperative complications functional recovery after surgery.MethodsThis single-centre retrospective cohort study included 884 inpatients elective Oral was assessed based number remaining teeth, use dentures, occlusal support, periodontal status. We related...
Single lung isografting in rats with pulmonary hypertension has been reported. However, it is hard to evaluate cardiopulmonary hemodynamics accurately or use circulatory assists during procedures using rats. Therefore, we tried establish a model of the beagle. Twenty young beagles were randomized into 3 groups. An injection dehydromonocrotaline 1.5 mg/kg (group 1, n = 7), 3.0 2, 10), 4.5 3, 3) was performed via right atrium. Two dogs group 2 and all died acute edema. During 8 weeks after...