A5067319030- Respiratory viral infections research
- Neonatal Respiratory Health Research
- Renal Diseases and Glomerulopathies
- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Virology and Viral Diseases
- Radioactive contamination and transfer
- Viral Infections and Immunology Research
- Influenza Virus Research Studies
- Viral gastroenteritis research and epidemiology
- Gestational Diabetes Research and Management
- Infectious Encephalopathies and Encephalitis
- Disaster Response and Management
- Pneumonia and Respiratory Infections
- Parvovirus B19 Infection Studies
- Risk Perception and Management
- Congenital Diaphragmatic Hernia Studies
- Viral Infections and Vectors
- Vasculitis and related conditions
- Radioactivity and Radon Measurements
- Platelet Disorders and Treatments
- Radiation Dose and Imaging
- Asthma and respiratory diseases
- Complement system in diseases
- Pediatric health and respiratory diseases
Fukushima Medical University
2016-2025
Fukushima Prefectural Culture Center
2017-2025
Southern Tohoku General Hospital
2023
Japan Pediatric Society
2020-2022
Suzuki (Japan)
2016-2021
Weatherford College
2021
Fukushima Medical University Hospital
2020
National Center For Child Health and Development
2017
Dokkyo Medical University
2016
Nagasaki University
2016
Background: The accidents that occurred at the Fukushima Daiichi Nuclear Power Plant after Great East Japan Earthquake on 11 March 2011 have resulted in long-term, ongoing anxiety among residents of Fukushima, Japan. Soon disaster, Prefecture launched Health Management Survey to investigate long-term low-dose radiation exposure caused by accident. Medical University took lead planning and implementing this survey. primary purposes survey are monitor health residents, promote their future...
On March 11, 2011, the Great East Japan Earthquake occurred in Japan, with a nuclear accident subsequently occurring at Fukushima Daiichi Nuclear Power Plant. The disaster forced many evacuees to change particular aspects of their lifestyles. This study assessed hypothesis that evacuation may have increased risk hypertension among residents Fukushima. A longitudinal examined data collected from 31 252 Japanese participants aged 40 74 years sourced general health checkups conducted 13...
Placenta accreta spectrum (PAS) is a life-threating complication in the field of obstetrics. Sometimes we face with unexpected PAS cases which potentially higher maternal mortality and morbidity compared expected cases. The present study was conducted to examine prevalence elucidate its risk factors using large Japanese birth cohort study. We reviewed results nationwide prospective Japan, identified 90,554 participants treated from 2011 2014 15 regional centers. Multiple regression models...
Abstract Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infection in young children and the second infant death worldwide. While global circulation has been extensively studied for viruses such as seasonal influenza, more recently also great detail SARS-CoV-2, lack multi-annual sampling complete RSV genomes limits our understanding molecular epidemiology. Here, we capitalise on genomic surveillance by INFORM-RSV study apply phylodynamic approaches to...
Nonpharmaceutical interventions for coronavirus disease (COVID-19), caused by severe acute respiratory syndrome 2, during the pandemic altered epidemiology of viruses. This study aimed to determine changes in viruses among children hospitalized from 2018 2023. Nasopharyngeal specimens were collected aged under 15 years with fever and/or symptoms admitted a medical institution Fukushima Prefecture between January and December Eighteen detected using real-time reverse transcription-polymerase...
Sulfated polysaccharides (i.e., dextran sulfate) and sulfated polymers polyvinylalcohol copolymers of acrylic acid with vinylalcohol) were found to be potent selective inhibitors the replication respiratory syncytial virus (RSV) influenza type A (influenza virus) but not other myxoviruses (parainfluenza 3, measles, B viruses). The compounds also inhibitory human immunodeficiency 1 (HIV-1) HIV-2 simian AIDS-related virus. mode antiviral action can attributed an inhibition binding cells...
A series of novel compounds, 5-alkynyl-1-beta-D-ribofuranosylimidazole-4- carboxamides, have been identified as broad-spectrum antiviral agents. 5-Ethynyl-1-beta-D-ribofuranosylimidazole-4- carboxamide (EICAR), the most potent congener group, showed potency about 10- to 100-fold greater than that ribavirin. Similar in spectrum ribavirin, EICAR was particularly active (50% inhibitory concentration, 0.2 4 micrograms/ml) against poxviruses (vaccinia virus), togaviruses (Sindbis and Semliki...
The Great East Japan Earthquake occurred on March 11, 2011, with a nuclear accident subsequently occurring at the Fukushima Daiichi Nuclear Power Plant. government ordered mandatory evacuation from high radioactive concentration area in Fukushima, which might have forced many evacuees to change particular aspects of their lifestyles. This study assessed hypothesis that mean body weight and proportion overweight/obese individuals would increase among after versus before disaster.A...
The Great East Japan Earthquake and Fukushima Daiichi nuclear disaster in 2011 forced the evacuation of a large number residents created changes lifestyle evacuees. These may have affected evacuees’ glucose metabolism, thereby leading to an increase incidence diabetes. This study included Japanese men women who were living near Nuclear Power Plant prefecture before disaster. Subjects subsequently underwent annual health checkups with focus on metabolic syndromes, which conducted under Health...
Thyroid nodules and cancers are rare in children compared with adults. However, after the 1986 Chernobyl Nuclear Power Plant accident, a rapid increase childhood thyroid cancer was observed. To avoid any confusion misunderstanding of data obtained Fukushima 2011 nuclear baseline prevalence should be carefully assessed standardized criteria systematically, comprehensively applied to population perceived at risk.Under official framework Health Management Survey, thyroids were examined using...
The hygiene hypothesis suggests that pet exposure is effective in preventing allergic disease, and some studies have reported the beneficial effects of dog during fetal development or early infancy on food allergy. However, to pets other than dogs kinds allergies remains unaddressed. This study aimed explore effect various species risk allergies. We obtained information allergy from Japan Environment Children's Study, a nationwide, prospective birth cohort included 97,413 mothers their...
Enterovirus 71 (EV71) is one of the major etiologic agents hand, foot and mouth disease (HFMD). The surveillance data indicate that EV71 infection follows an epidemic mode transmission, causing large outbreaks then becoming quiescent for a few years.We investigated genetic diversity total 121 strains isolated from patients with HFMD in Fukushima, Japan, 1983 to 2003 compared their relation 164 world using phylogenetic analysis based on VP4 sequence.We observed EV71-related Fukushima 1984,...
We examined the efficacy of neuraminidase inhibitors for reducing duration virus shedding after naturally occurring influenza infection. The fever was significantly shorter in patients treated with than untreated patients. durations from were not those
The sulphated polymers, such as polyvinylalcohol sulphate (PVAS) and its co-polymer with acrylic acid (PAVAS), have proved to be potent inhibitors for herpes simplex virus, human cytomegalovirus, vesicular stomatitis respiratory syncytial Sindbis Semliki Forest Junin Tacaribe murine sarcoma virus immunodeficiency virus. They are not inhibitory non-enveloped viruses, poliovirus reovirus. broad-spectrum antiviral effects of these compounds depend on their molecular weight degree sulphation....
In Japan, mean maternal age at first childbirth is increasing. The aim of this study was to investigate whether the a risk factor for preterm birth (PTB), low weight (LBW), and small gestational (SGA).
Japan Environment and Children's Study (JECS) is nationwide birth cohort study that was initiated in January 2011 to investigate the effect of environmental factors on children's health. Soon after JECS started, Great East Earthquake occurred March 11, 2011, with subsequent nuclear accident at Fukushima Daiichi Nuclear Power Plant, causing catastrophic damage Prefecture. After disaster, relaunched cover all areas Prefecture due public concern. In this study, we used results individuals...
After the Great East Japan Earthquake, over 160,000 residents near Fukushima Daiichi Nuclear Power Plant were forced to evacuate due a nuclear accident. Health problems in these evacuees have since become major issues. We examined association between evacuation and incidence of metabolic syndrome (METS) among Fukushima.We conducted cohort study aged 40-74 years without METS at time disaster Fukushima. Among 20,269 who met inclusion criteria before disaster, 8,547 (3,697 men 4,850 women;...
Abstract Introduction This study evaluated the risk of preterm birth, low birthweight and small‐for‐gestational‐age neonates born to mothers with adenomyosis during pregnancy. Material methods We used results a Japanese nationwide prospective birth cohort study, identifying 93 668 singleton deliveries from 2011 2014. identified 314 pregnancies using self‐reported questionnaires. Multiple logistic regression analyses were conducted examine whether was associated adverse pregnancy outcome....