Katsuki Hirai

ORCID: 0000-0003-2768-2489
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About
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Research Areas
  • Infectious Encephalopathies and Encephalitis
  • Sepsis Diagnosis and Treatment
  • Kawasaki Disease and Coronary Complications
  • Intensive Care Unit Cognitive Disorders
  • Emergency and Acute Care Studies
  • Clinical practice guidelines implementation
  • Mechanical Circulatory Support Devices
  • Cardiac Structural Anomalies and Repair
  • Airway Management and Intubation Techniques
  • Influenza Virus Research Studies
  • Pediatric Urology and Nephrology Studies
  • Coronary Artery Anomalies
  • Respiratory viral infections research
  • Vasculitis and related conditions
  • Anesthesia and Neurotoxicity Research
  • Viral Infections and Vectors
  • Neurosurgical Procedures and Complications
  • Epilepsy research and treatment
  • Nosocomial Infections in ICU
  • Cardiovascular Issues in Pregnancy
  • Burn Injury Management and Outcomes
  • Anesthesia and Sedative Agents
  • Restraint-Related Deaths
  • Global Maternal and Child Health
  • Sarcoidosis and Beryllium Toxicity Research

Japanese Red Cross Kumamoto Hospital
2015-2025

Honda (Japan)
2022

Genetic Analysis (Norway)
2022

The Japanese Society of Intensive Care Medicine
2010

Nagano Children's Hospital
2006

10.1016/s0140-6736(18)32003-8 article EN The Lancet 2019-03-01

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016), a Japanese-specific set clinical practice guidelines sepsis septic shock created jointly by the Society Intensive Care Medicine Association Acute Medicine, was first released in February 2017 published Journal JSICM, [2017; Volume 24 (supplement 2)] https://doi.org/10.3918/jsicm.24S0001 28, 1)] http://onlinelibrary.wiley.com/doi/10.1002/jja2.2017.28.issue-S1/issuetoc . This abridged...

10.1186/s40560-017-0270-8 article EN cc-by Journal of Intensive Care 2018-02-02

Background and Purpose The Japanese Clinical Practice Guidelines for Management of Sepsis Septic Shock 2016 (J‐ SSCG 2016), a Japanese‐specific set clinical practice guidelines sepsis septic shock created jointly by the Society Intensive Care Medicine Association Acute Medicine, was first released in February 2017 Japanese. An English‐language version these based on contents original Japanese‐language version. Methods Members were selected organized into 19 committee members 52 working group...

10.1002/ams2.322 article EN cc-by Acute Medicine & Surgery 2018-01-01

We report the case of a 4-year-old boy with no significant past medical history who was brought to our hospital by ambulance, presenting 3-day fever and cough. He presented severe hypoxemia marked work breathing, SpO2 below 90% on 10 L/min via reservoir mask. Breath sounds were reduced, his chest X-ray revealed near-total opacification left lung (Figure 1a). Venous blood gas analysis showed CO2 retention. intubated mechanically ventilated immediately. The partial pressure arterial oxygen...

10.1002/ppul.71002 article EN Pediatric Pulmonology 2025-02-01

Abstract We aimed to investigate whether ventilator support time influences the occurrence of dysphagia in pediatric trauma patients. This case-series study was conducted a single emergency and critical care center from April 2012 March 2022. Trauma patients aged < 16 years who underwent tracheal intubation were divided into two groups based on within 72 h after extubation, their data analyzed. Tracheal performed 75 patients, 53 them included analysis. A total 22 had post-extubation head...

10.1038/s41598-024-54247-x article EN cc-by Scientific Reports 2024-02-12

Respiratory syncytial virus (RSV) infection is a major cause of hospitalization during the winter among infants and young children. In 2002 palivizumab was introduced to high-risk for RSV in Japan. It important characterize hospitalized children due after introduction palivizumab.A survey conducted collect data from at 12 participating hospitals 2007.From October 2007 through April 2008, 8163 were admitted hospitals, with accounting 811 those hospitalizations. Mean age 12.4 ± 12.7 months,...

10.1111/j.1442-200x.2010.03249.x article EN Pediatrics International 2010-09-14

Japanese encephalitis (JE) is the leading cause of viral with high mortality and morbidity in Asia. In Japan, however, active recommendation JE vaccine was retracted 2005 because potential risk acute disseminated encephalomyelitis. We aimed to determine recent incidence childhood-onset after domestic change vaccination policy analyze clinical features affected children. A retrospective nationwide survey conducted for pediatric patients Japan from 1995 2015. The national surveillance system...

10.1093/cid/ciy816 article EN Clinical Infectious Diseases 2018-09-18

Enterovirus D68 (EV-D68) causes respiratory illnesses such as pneumonia, and has been reported to cause acute flaccid myelitis. A71 (EV-A71) is known cardiopulmonary failure due brainstem encephalitis, but there have few reports of these conditions being associated with EV-D68. Outbreaks EV-D68 infection occurred in the USA, Canada, Europe Asia. Clinical management largely supportive are no specific antivirals available. The case patient, a 4-year-old girl, had encephalitis. was isolated...

10.1136/bcr-2019-231990 article EN BMJ Case Reports 2019-11-01

Rationale: Vanishing bile duct syndrome (VBDS) is the acquired progressive destruction and disappearance of intrahepatic interlobular ducts in absence underlying liver or biliary tract disease, causing chronic cholestasis. Infections, drugs, toxins, malignant diseases, certain immunological processes are associated with development this syndrome. There have been no reports children developing VBDS as a consequence administration L-carbocisteine. Patient concerns: A 9-year-old Japanese girl...

10.1097/md.0000000000031486 article EN cc-by-nc Medicine 2022-11-11

採択日 2016 年 3 月 7 日 要約:熊本県下の小児重症患者診療に携わる全ての診療科 (15 病院 24 科) を対象として,2010 年に生じた 16 歳未満の小児重症患者の調査を行った。 回答率は 96%, 小児重症患者は 386 人で, ICU へ入室した小児重症患者において,予定入室は 160 人,緊急入室 114 人であり,一般病棟 管理 92 人,院外心肺停止患者 20 人であった。熊本県における小児重症患者の発生率は,16 歳 未満人口 1,000 人あたり 1.44 人で,日本では 25,200 人 / 年の小児重症患者が発生すると推測さ れた。これらの発生率は海外や日本の既報告と同等であり,今後,日本での PICU 必要病床数 の根拠になりうると考えられた。

10.3918/jsicm.23.679 article JA Journal of the Japanese Society of Intensive Care Medicine 2016-01-01

Pathogenic variants of ectodysplasin A (EDA) gene are responsible for the development hypohidrotic ectodermal dysplasia (HED) and energy dysmetabolism. Patients with HED develop hyperthermia dry skin owing to hypohidrosis. Influenza-associated encephalopathy (IAE) is characterized by developing impaired consciousness within a few days after influenza infection. 4-year-old boy demonstrated IAE. He experienced frequent episodes fever exhibited typical features such as sparse hair,...

10.1016/j.bdcasr.2024.100018 article EN cc-by-nc-nd Brain and Development Case Reports 2024-06-01

要旨 単一施設の上部尿路感染症(upper urinary tract infection以下UUTI) におけるextended-spectrum β-lactamase (ESBL)産生菌の関与について検討した。A 群:ESBL 産生菌群とB 産生菌以外のUUTI 群の2 群に分け,分離状況と年度別推移,年齢と性別,抗菌薬の感受性と投与期間,尿路奇形を主体とする基礎疾患の有無,予防内服の影響に関して比較検討した。対象は2009 年4 月1 日から2014 年3 月31 日までの5 年間の166 例で,A群は28例,B群は138例であった。年度別推移は,2009 年21 例(うちESBL 症例4 例)(以下( )内はESBL症例数を示す),2010年20 例(3 例),2011年28 例(1 例),2012年40 例(8 例),2013年57 例(12 例)であり,UUTI,ESBL 産生菌によるUUTI 症例共に増加していた。A 群の28例中12例に,感受性が耐性の抗菌薬を選択し,抗菌薬は変更せずに治療を終了した。1 例が,severe...

10.3165/jjpn.28.37 article JA Japanese journal of pediatric nephrology 2015-01-01

Background: Thiamylal exerts excellent sedative effects. However, it is not routinely used because of its serious adverse This study aimed to clarify the target blood concentration range and infusion rate thiamylal in children by measuring evaluating relationship with efficacy Methods: was approved Ethics Committee Japanese Red Cross Kumamoto Hospital. The authors included 10 aged between 1 7 years who had received continuous intravenous (IV) for management refractory status epilepticus,...

10.1097/ftd.0000000000001153 article EN Therapeutic Drug Monitoring 2023-11-27

【目的】日本集中治療医学会新生児・小児集中治療委員会の事業として,我が国での2009年豚由来A型新型インフルエンザ(A/H1N1 pdm)流行初期の小児重症症例の集積を試みた。【方法】対象は2009年8~10月にH1N1感染が確認され,ICUで人工呼吸を要した15歳未満の患者について,所定の様式に従い情報提供された。【結果】合計9症例(年齢中央値5歳3か月)であった。Pediatric Index of Mortality-2スコアによる平均予測死亡率15.4%に対し,実死亡率は0%であった。人工呼吸適用理由は5症例が呼吸不全(喘息・気管支炎,肺炎),3症例が意識障害(脳症),1症例が循環不全(心筋炎)であった。2症例で体外式心肺補助を必要とした。全症例でリン酸オセルタミビルが投与され,開始日中央値は発症1日後であった。【結語】今後,さらなる症例集積と統計学的手法を取り入れた追加解析を行い,診断治療指針の確立につながる知見を提示する必要がある。

10.3918/jsicm.17.87 article JA Journal of the Japanese Society of Intensive Care Medicine 2010-01-01

Abstract Background Adenovirus gastroenteritis is a common cause of diarrhea and vomiting in infants, resulting prerenal acute kidney injury (AKI). However, postrenal AKI due to urinary stones associated with adenovirus extremely rare. Here, we describe obstructive ammonium acid urate gastroenteritis. Case presentation A previously healthy 6-month-old boy had an 11-day history severe 5-day vomiting. His stool was positive for antigens. We initiated fluid replacement therapy. On the second...

10.1186/s12894-022-00954-4 article EN cc-by BMC Urology 2022-01-15

Airway management in children with severe burns is difficult because of airway edema and prolonged duration ventilatory management. There insufficient evidence to suggest that tracheostomy beneficial for children.A male child aged 1 year 4 months was injured when he accidentally fell into a bathtub filled boiling water. Furthermore, 85% the burnt area, including face neck, consisted second-degree burns; hence, oral tracheal intubation resuscitative infusion were required. In this case,...

10.1186/s12245-022-00451-3 article EN cc-by International Journal of Emergency Medicine 2022-09-05
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