A5026798135- Trauma and Emergency Care Studies
- Cardiac Arrest and Resuscitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Emergency and Acute Care Studies
- Sepsis Diagnosis and Treatment
- Injury Epidemiology and Prevention
- Abdominal Trauma and Injuries
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Non-Invasive Vital Sign Monitoring
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Trauma Management and Diagnosis
- Intensive Care Unit Cognitive Disorders
- Blood Coagulation and Thrombosis Mechanisms
- Respiratory Support and Mechanisms
- Optical Imaging and Spectroscopy Techniques
- Hemodynamic Monitoring and Therapy
- COVID-19 and healthcare impacts
- Nosocomial Infections in ICU
- Influenza Virus Research Studies
- Hemophilia Treatment and Research
- Respiratory viral infections research
- Data-Driven Disease Surveillance
- Poisoning and overdose treatments
- Micro and Nano Robotics
- Immune Response and Inflammation
Osaka University
2016-2025
Osaka Police Hospital
2016-2021
Osaka University Hospital
2012-2021
Line Corporation (Japan)
2021
Osaka Prefectural Medical Center
2017-2020
Osaka National Hospital
2020
Osaka City General Hospital
2020
Kyoto Prefectural University of Medicine
2020
Kyoto University
2020
Otsuma Women's University
2020
P001 - Sepsis impairs the capillary response within hypoxic capillaries and decreases erythrocyte oxygen-dependent ATP efflux R. M. Bateman, D. Sharpe, J. E. Jagger, C. G. Ellis P002 Lower serum immunoglobulin G2 level does not predispose to severe flu. Solé-Violán, López-Rodríguez, Herrera-Ramos, Ruíz-Hernández, L. Borderías, Horcajada, N. González-Quevedo, O. Rajas, Briones, F. Rodríguez de Castro, Gallego P003 Brain protective effects of intravenous through inhibition complement...
Sepsis remains a major cause of death. Cytokines interact closely with each other and play crucial role in the progression sepsis. We focussed on associations cytokine network prognosis disease severities This retrospective study included 31 patients sepsis 13 healthy controls. Blood samples were collected from days 1, 2, 4, 6, 8, 11 15 Levels PAI-1, IFN-α, IFN-γ, IL-1β, IL-6, IL-8, IL-12/IL-23p40, IL-17A, TNF-α, MCP-1, IL-4 IL-10 measured. SOFA, JAAM DIC ISTH scores evaluated at same times...
Abstract Introduction Cross-talk between the coagulation system and inflammatory reactions during sepsis causes organ damage followed by multiple dysfunction syndrome or even death. Therefore, anticoagulant therapies have been expected to be beneficial in treatment of severe sepsis. Recombinant human soluble thrombomodulin (rhTM) binds thrombin inactivate coagulation, thrombin-rhTM complex activates protein C produce activated C. The purpose this study was examine efficacy rhTM for treating...
Background Resuscitative endovascular balloon occlusion of the aorta (REBOA) performed by emergency physicians has been gaining acceptance as a less invasive technique than resuscitative thoracotomy. Objective To evaluate access-related complications and duration occlusions during REBOA. Methods Patients with haemorrhagic shock requiring REBOA, from 18 hospitals in Japan, included DIRECT-IABO Registry were studied. REBOA-related characteristics compared between non-survivors survivors at 24...
Neutrophil extracellular traps (NETs), a newly identified immune mechanism, are induced by inflammatory stimuli. Modification citrullination of histone H3 is thought to be involved in the vitro formation NETs. The purposes this study were evaluate whether NETs and citrullinated (Cit-H3) present bloodstream critically ill patients identify correlations with clinical biological parameters. Blood samples collected from intubated at time ICU admission April June 2011. To NETs, DNA visualized...
The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016), a Japanese-specific set clinical practice guidelines sepsis septic shock created jointly by the Society Intensive Care Medicine Association Acute Medicine, was first released in February 2017 published Journal JSICM, [2017; Volume 24 (supplement 2)] https://doi.org/10.3918/jsicm.24S0001 28, 1)] http://onlinelibrary.wiley.com/doi/10.1002/jja2.2017.28.issue-S1/issuetoc . This abridged...
The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020), a Japanese-specific set clinical practice guidelines sepsis septic shock created as revised from J-SSCG 2016 jointly by the Society Intensive Care Medicine Association Acute Medicine, was first released in September published February 2021. An English-language version these based on contents original Japanese-language version. purpose this guideline is to assist medical staff making...
We have designed and synthesized a pyridine-based tripodal anchor unit to construct single-molecule junction with gold electrode. The advantage of anchoring surface was unambiguously demonstrated by cyclic voltammetry measurements. X-ray photoelectron spectroscopy measurements indicated that the π orbital pyridine contributes physical adsorption surface. conductance consists diphenyl acetylene measured modified scanning tunneling microscope techniques successfully determined be 5 ± 1 ×...
Background and Purpose The Japanese Clinical Practice Guidelines for Management of Sepsis Septic Shock 2016 (J‐ SSCG 2016), a Japanese‐specific set clinical practice guidelines sepsis septic shock created jointly by the Society Intensive Care Medicine Association Acute Medicine, was first released in February 2017 Japanese. An English‐language version these based on contents original Japanese‐language version. Methods Members were selected organized into 19 committee members 52 working group...
Background The novel corona virus (COVID-19) pandemic occurred worldwide. Although an excessive burden was placed on emergency medical institutions treating urgent and severe patients, its impact patient outcome remains unknown. This study aimed to assess the of COVID-19 in 2021 services (EMS) system outcomes Osaka Prefecture, Japan. Methods a retrospective descriptive with period from January 1, 2019 December 31, 2021. We included patients who were transported by ambulance had cleaned data...
Pyrethroid insecticides are widely used because of their low toxicity in humans. Spray-type pyrethroids often formulated with kerosene as a carrier solvent, and inhalation kerosene-containing products can lead to pneumonitis the formation lung abscesses. We report case chemical resulting development abscess due intentional pyrethroids. A man his 50s psychiatric hospital for transient psychotic disorder attempted suicide during an overnight leave from hospital. He drank sodium hypochlorite,...
The impact of time day or week on the survival emergency trauma patients is still controversial. purpose this study was to evaluate outcomes these according admission by using data from nationwide Japan Trauma Data Bank (JTDB).This enrolled 236,698 registered in JTDB database 2004 2015, and defined daytime as 09:00 AM 16:59 PM nighttime 17:00 08:59 AM, weekdays Monday Friday, weekends Saturday, Sunday, national holidays. outcome measures were death room (ER) discharge death.In total, 170,622...
Cytokines compose a network and play crucial roles in the pathogenesis prognosis of sepsis. Adipose tissue is an important immune endocrine organ that releases adipocytokines. This study aimed to evaluate adipocytokines sepsis from perspective.This retrospective 37 patients with 12 healthy controls was conducted February 2014 July 2015. Blood samples were collected on days 1 (within 24 h diagnosis), 2, 4, 6, 8, 11, 15 controls. Adipocytokines (adiponectin, leptin, resistin, chemerin,...
Objective Neutrophils are able to form ‘neutrophil extracellular traps’ (NETs), which they use trap and kill pathogens such as bacteria fungi at the foci of infection. This observational study investigated presence NETs in blood from critically ill patients healthy volunteers. Methods Fluorescent triple-colour immunocytochemical analysis smears collected with systemic inflammatory response syndrome (SIRS; associated various clinical conditions) who had been hospitalized intensive care unit,...
BackgroundCerebral oximetry (rSO2) may be useful in assessing the probability of return spontaneous circulation (ROSC). However, potential trend rSO2 value has not been discussed when determining ROSC.MethodsThis was a retrospective study out-of-hospital cardiac arrest (OHCA) patients with continuous values recorded during cardiopulmonary arrest. We used logistic regression analysis at each time point to investigate best subsets rSO2-related variables for ROSC, which included (baseline),...
The aim of our study is to describe the characteristics patients who use emergency medical services (EMS), EMS performance, and regional variations in Japan.We undertook a nationwide, population-based, descriptive review anonymized ambulance transport records obtained from Fire Disaster Management Agency Japan. All transported institutions by personnel January December 2016 were enrolled this study, excluding not transported.During period, 5,097,838 hospital. Their median age was 69 years,...
Isolated traumatic spinal cord injury (t-SCI) and brain (TBI) represent significant public health concerns, resulting in long-term disabilities necessitating sophisticated care, particularly when occurring concurrently. The impact of these combined injuries, while crucial trauma management, on clinical, socioeconomic, care outcomes is largely unknown. To address this gap, our secondary retrospective cohort study used data from the Japan Trauma Data Bank, covering patients enrolled over a...
Despite advances in therapeutic strategies and improved guidelines, morbidity mortality rates for out-of-hospital cardiac arrest (OHCA) remain high. Especially, neurological prognosis is one of the most important problems even though brain protection therapy patients with OHCA has greatly recent years due to development emergency post-cardiac interventions such as mild hypothermia, early percutaneous coronary intervention, extracorporeal cardiopulmonary resuscitation (CPR). Recently,...
In recent years, the measurement of cerebral regional oxygen saturation (rSO2) during resuscitation has attracted attention. The objective this study was to clarify relationship between serial changes in rSO2 values extracorporeal cardiopulmonary (ECPR) and neurological outcome.We measured patients with out-of-hospital cardiac arrest before after ECPR Osaka National Hospital.From January 2013 through March 2015, were evaluated 16 patients. Their outcomes, as by Glasgow Outcome Scale (GOS)...