A5062313548- Intensive Care Unit Cognitive Disorders
- Sepsis Diagnosis and Treatment
- Multiple Sclerosis Research Studies
- Myasthenia Gravis and Thymoma
- Neuroinflammation and Neurodegeneration Mechanisms
- Antifungal resistance and susceptibility
- Photosynthetic Processes and Mechanisms
- Traumatic Brain Injury and Neurovascular Disturbances
- Ocular Diseases and Behçet’s Syndrome
- Light effects on plants
- Peripheral Neuropathies and Disorders
- Neurogenesis and neuroplasticity mechanisms
- Medicinal Plants and Bioactive Compounds
- Parkinson's Disease and Spinal Disorders
- Trauma and Emergency Care Studies
- Sphingolipid Metabolism and Signaling
- Microtubule and mitosis dynamics
- Ginkgo biloba and Cashew Applications
- Mesenchymal stem cell research
- Systemic Lupus Erythematosus Research
- Immune Response and Inflammation
- Polyomavirus and related diseases
- Vagus Nerve Stimulation Research
- Autoimmune Neurological Disorders and Treatments
- Photoreceptor and optogenetics research
Biomedical Research Networking Center on Neurodegenerative Diseases
2023
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2023
Universitat de Barcelona
2023
Medizinische Hochschule Hannover
2022
Istanbul University
2013-2018
The University of Texas Medical Branch at Galveston
2016
Society for Neuroscience
2014
P001 - Sepsis impairs the capillary response within hypoxic capillaries and decreases erythrocyte oxygen-dependent ATP efflux R. M. Bateman, D. Sharpe, J. E. Jagger, C. G. Ellis P002 Lower serum immunoglobulin G2 level does not predispose to severe flu. Solé-Violán, López-Rodríguez, Herrera-Ramos, Ruíz-Hernández, L. Borderías, Horcajada, N. González-Quevedo, O. Rajas, Briones, F. Rodríguez de Castro, Gallego P003 Brain protective effects of intravenous through inhibition complement...
Extracellular vesicles (EVs) play an important role in intercellular communication as carriers of signalling molecules such bioactive miRNAs, proteins and lipids. EVs are key players the functioning central nervous system (CNS) by influencing synaptic events modulating recipient neurons. However, specific neuron-to-neuron via is still not well understood. Here, we provide evidence that primary neurons uptake neuron-derived soma, dendrites, even dendritic spines, carry proteins....
Sepsis-induced brain dysfunction (SIBD) has been neglected until recently due to the absence of specific clinical or biological markers. There is increasing evidence that sepsis may pose substantial risks for long term cognitive impairment.To find out and inflammatory factors associated with acute SIBD serum levels cytokines, complement breakdown products neurodegeneration markers were measured by ELISA in sera 86 patients 33 healthy controls. Association between these test results was...
Myasthenia gravis (MG) is an antibody-mediated autoimmune disease of the neuromuscular junction (NMJ), mostly associated with acetylcholine receptor (AChR) antibodies. Around 5–10 % MG patients show antibodies to muscle-specific tyrosine kinase (MuSK). Mesenchymal stem cell (MSC) administration has been shown ameliorate muscle weakness in experimental myasthenia (EAMG) model induced by AChR immunization. To investigate efficacy treatment MuSK-related EAMG, clinical and immunological features...
Intravenous (IV) immunoglobulin (Ig) treatment is known to alleviate behavioral deficits and increase survival in the experimentally induced model of sepsis. To delineate mechanisms by which IVIg prevents neuronal dysfunction, an array immunological apoptosis markers was investigated.Sepsis cecal ligation perforation (CLP) rats. The animals were divided into five groups: sham, control, CLP + saline, G (IgG) (250 mg/kg, iv), immunoglobulins enriched with M (IgGAM) iv). Blood brain samples...
Abstract Altered long-range connectivity is a common finding across neurodevelopmental psychiatric disorders, but causes and consequences are not well understood. Genetic variation in ST8SIA2 has been associated with schizophrenia, autism, bipolar disorder, St8sia2 −/− mice show number of related behavioral phenotypes. In the present study, we use conditional knockout (cKO) to dissect defects deficiency cortical interneurons, their environment, or di- mesencephalon. Neither separate nor...
Sensory photoreceptors abound in nature and enable organisms to adapt behavior, development, physiology environmental light. In optogenetics, allow spatiotemporally precise, reversible, non-invasive control by light of cellular processes. Notwithstanding the development numerous optogenetic circuits, an unmet demand exists for efficient circuits sensitive red light, given its superior penetration biological tissue. Bacteriophytochrome sense ratio far-red regulate activity enzymatic effector...
<b><i>Objective:</i></b> This study was conducted to identify a biomarker for multiple sclerosis (MS) that can be used as predictor of relapse and disability. <b><i>Materials Methods:</i></b> Sera 26 consecutive relapsing-remitting MS (RRMS) patients were screened switch-associated protein 70 (SWAP-70) antibody, which previously identified by macroarray. The serum levels several cytokines, chemokines soluble adhesion molecules related attacks...
Sensory photoreceptors abound in nature and enable organisms to adapt behavior, development, physiology environmental light. In optogenetics, allow spatiotemporally precise, reversible, non-invasive control by light of cellular processes. Notwithstanding the development numerous optogenetic circuits, an unmet demand exists for efficient circuits sensitive red light, given its superior penetration biological tissue. Bacteriophytochrome sense ratio far-red regulate activity enzymatic effector...