A5017303419- Myasthenia Gravis and Thymoma
- Antifungal resistance and susceptibility
- Peripheral Neuropathies and Disorders
- Chronic Obstructive Pulmonary Disease (COPD) Research
- COVID-19 Clinical Research Studies
- Intracranial Aneurysms: Treatment and Complications
- Monoclonal and Polyclonal Antibodies Research
- Long-Term Effects of COVID-19
- Respiratory Support and Mechanisms
- Dialysis and Renal Disease Management
- Pneumonia and Respiratory Infections
- Cystic Fibrosis Research Advances
- Sepsis Diagnosis and Treatment
- Medical Imaging and Pathology Studies
- Vascular Malformations Diagnosis and Treatment
- Soft tissue tumor case studies
- Emergency and Acute Care Studies
- Meningioma and schwannoma management
- Inflammatory Biomarkers in Disease Prognosis
- Lung Cancer Research Studies
- Cerebrovascular and Carotid Artery Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Nicotinic Acetylcholine Receptors Study
- Respiratory viral infections research
- Histone Deacetylase Inhibitors Research
Sismanoglio General Hospital
2011-2024
General Hospital of Attica
2015-2023
Laiko General Hospital of Athens
2020-2022
National and Kapodistrian University of Athens
1999-2022
Mitera Hospital
2020-2022
Hygeia Hospital
2022
St Savas Hospital
2021
Pasteur Hellenic Institute
2007-2018
Institut Pasteur
1991-2014
University of Patras
2011
Mycoplasmas, the smallest self‑replicating prokaryotes without a cell wall, are most prevalent and extensively studied species in humans. They significantly contribute to chronic respiratory tract illnesses pneumonia, with children adolescents being particularly vulnerable. <em>Mycoplasma</em> <em>pneumoniae</em> (<em>M</em>. <em>pneumoniae</em>) infections typically tend be self‑limiting mild but can progress severe or even life‑threatening conditions certain individuals. Extrapulmonary...
Myasthenia gravis (MG) is an autoimmune disease caused by antibody mediated impairment in the neuromuscular junction. Seronegative MG (SNMG) without antibodies against acetylcholine receptor (AChR) and muscle-specific kinase (MuSK) routine assays accounts for about 20% of all patients.Plasma from 81 Chinese patients previously found to be seronegative was tested AChR MuSK antibodies. These samples were screened (i) a novel, highly sensitive radioimmunoassay antibodies; (ii) cell-based...
Immature granulocytes (IGs) include metamyelocytes, myelocytes and promyelocytes, are the precursors of neutrophils. Increased IG counts found in peripheral blood indicate an enhanced bone marrow activity. In addition, IGs have been evaluated numerous clinical conditions, such as severe acute pancreatitis, systemic inflammatory response syndrome infectious complications following open‑heart surgery under cardiopulmonary bypass. Neutrophils considered to play a crucial role host defense...
One of the most important tasks in Emergency Department (ED) is to promptly identify patients who will benefit from hospital admission. Machine Learning (ML) techniques show promise as diagnostic aids healthcare.Our objective was find an algorithm using ML assist clinical decision-making emergency setting.We assessed following features seeking investigate their performance predicting admission: serum levels Urea, Creatinine, Lactate Dehydrogenase, Creatine Kinase, C-Reactive Protein,...
Eosinophils are blood cells responsible for response against parasites and allergens. Eosinophil to lymphocyte ratio (ELR) is a biomarker inflammatory conditions. Our aim was evaluate the role of eosinophils ELR in COVID-19 patients.The study included 96 patients hospitalized with COVID-19. They were classified into moderate severe cases critical cases. determined both groups, that died or survived correlated duration hospitalization.There statistically significant decrease between (p<0.05),...
Low levels of serum calcium, elevated phosphorus and absent or abnormally low parathyroid hormone characterize hypoparathyroidism, a rare endocrine deficiency illness. Hypoparathyroidism is caused by injury to the gland as result surgery autoimmune disease. In addition, hypoparathyroidism may develop due genetic causes infiltrative diseases. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection characterized multi-organ involvement, including dysfunction glands. Previous...
Myasthenia gravis (MG) is an antibody-mediated autoimmune disease of the neuromuscular junction (NMJ), mostly associated with acetylcholine receptor (AChR) antibodies. Around 5–10 % MG patients show antibodies to muscle-specific tyrosine kinase (MuSK). Mesenchymal stem cell (MSC) administration has been shown ameliorate muscle weakness in experimental myasthenia (EAMG) model induced by AChR immunization. To investigate efficacy treatment MuSK-related EAMG, clinical and immunological features...
Myasthenia gravis (MG) is usually caused by autoantibodies against muscle nicotinic acetylcholine receptor (AChR), which composed of five subunits (alpha(2)betagammadelta or alpha(2)betaepsilondelta). Current treatments, including plasmapheresis, are nonspecific, causing several side effects. We aim to develop an antigen-specific alternative since the latter removes indispensable plasma components in addition anti-AChR antibodies. developing a method for selective depletion from patients'...
Coronavirus disease 2019 (COVID-19) is characterized by poor outcomes and a high mortality rate, particularly among elderly patients. Since the beginning of pandemic, an older age has been recognized as critical risk factor for severity, with increasing rates in each decade life. This phenomenon may be consequence previous health status, higher prevalence pre-existing comorbidities degree frailty. The majority studies on factors patients refer to first waves pandemic predictors in-hospital...
The objective of this study was to establish a machine learning model and evaluate its predictive capability admission the hospital. This observational retrospective included 3204 emergency department visits public tertiary care hospital in Greece from 14 March 4 May 2019. We investigated biochemical markers coagulation tests that are routinely checked patients visiting Emergency Department (ED) relation ED outcome (admission or discharge). Among most popular classification techniques...