Mehmet Gençer

ORCID: 0000-0003-3813-2052
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Research Areas
  • Multiple Sclerosis Research Studies
  • Peripheral Neuropathies and Disorders
  • Systemic Sclerosis and Related Diseases
  • Tuberculosis Research and Epidemiology
  • Neurogenesis and neuroplasticity mechanisms
  • Migraine and Headache Studies
  • Parasitic infections in humans and animals
  • Monoclonal and Polyclonal Antibodies Research
  • Sleep and Wakefulness Research
  • Asthma and respiratory diseases
  • Peripheral Nerve Disorders
  • Infectious Diseases and Tuberculosis
  • Paraoxonase enzyme and polymorphisms
  • Apelin-related biomedical research
  • Polyomavirus and related diseases
  • Nuclear Receptors and Signaling
  • Autoimmune Neurological Disorders and Treatments
  • Cancer Diagnosis and Treatment
  • Health and Well-being Studies
  • Nicotinic Acetylcholine Receptors Study
  • Parkinson's Disease and Spinal Disorders
  • Public Administration and Governance
  • Cynara cardunculus studies
  • Cerebrovascular and genetic disorders
  • Diagnosis and treatment of tuberculosis

İstanbul Başakşehir Çam ve Sakura Şehir Hastanesi
2024

Creative Commons
2021

Haydarpaşa Numune Eğitim ve Araştırma Hastanesi
2011-2021

Istanbul University
2017-2021

Kocaeli Üniversitesi
2011

Turkish Society of Hematology
2010

Harran University
2005-2006

Chest Diseases Hospital
1998-2004

Van Yüzüncü Yıl Üniversitesi
2002

There is a growing interest in the understanding of possible role DNA repair systems ageing and neurodegenerative diseases after damage observed brain individuals affected by diseases. In light these findings, we investigated whether gene polymorphisms (XRCC1 Arg399Gln, XRCC3 Thr241Met XPD Lys751Gln, XPG Asp1104His, APE1 Asp148Glu, HOGG1 Ser326Cys) account for an increased risk Parkinson's disease (PD).The present analyses are based on 60 case subjects with PD 108 unrelated healthy controls....

10.1089/gtmb.2011.0252 article EN Genetic Testing and Molecular Biomarkers 2012-01-06

Migraine is a primary headache disorder which involves both genetic and environmental components. Since angiotensin-converting enzyme (ACE) matrix metalloproteinase (MMP) share the same homology, we investigated whether MMP-3 ACE I/D gene variants are involved in migraine risk variant might act combination with patients migraine. This first study to evaluate association between polymorphisms, Genotypes were determined by polymerase chain reaction. The frequencies of 5A5A genotypes D allele...

10.1111/j.1468-2982.2006.01269.x article EN Cephalalgia 2007-01-25

Abstract We investigated the association of PON1 55/192 polymorphisms with type, severity and prognosis stroke oxidative markers. Paraoxonase1 (PON1), Glutathione Reductase (GSH‐Rd) Malondialdehyde (MDA) levels were measured at day 1 5 following onset stroke. Genotypes determined by polymerase chain reaction restriction digestion. The frequencies QQ MM genotypes 192 55, respectively, significantly higher in controls than patients. However, allele R 55 L more frequent patients compared to...

10.1080/15216540600688462 article EN IUBMB Life 2006-03-01

In this article, we report on a 40-year-old man with relapsing polychondritis (RP) of the tracheobronchial tree without clinical manifestations other systems including nasal septum and earlobe cartilage involvement. The illness was diagnosed histologically, treatment procaine penicillin successful. RP is an unusual systemic disorder characterized by widespread inflammation destruction tissues. main cause usually autoimmune. various chondritis, arthritis, scleritis, damage to tracheal...

10.1159/000029262 article EN Respiration 1998-01-01

Asthma is a chronic inflammatory disease of the airways. Inhaled corticosteroids are very important in anti-inflammatory treatment, but to great extent they cannot control asthma alone. In addition corticosteroids, long-acting beta2 agonists and leukotriene antagonists used for control.In this study, effect formoterol montelukast on patients with moderately persistent who were symptomatic while using low dose inhaled budesonide was compared.At beginning 40 400 microg/day 4-week training...

10.1159/000081760 article EN Respiration 2004-01-01

In this study we have reported a 12-year old girl patient who visited out-patient clinic with the history of headache and convulsion. The was diagnosed as miliary tuberculosis multiple brain tuberculomas. Miliary infiltration observed in chest x-ray high-resolution thorax computed tomography (CT), tuberculomas surrounded wide edema Magnetic Resonance Imaging (MRI). Acid-fast bacilli were detected inducted sputum gastric fluid. Focal epileptiform activity seen electroencephalography (EEG)....

10.1620/tjem.205.367 article EN The Tohoku Journal of Experimental Medicine 2005-01-01

Context/Objective: Clinical disease activity in multiple sclerosis (MS) may manifest as predominant involvement of optic nerves and spinal cord, exemplified by opticospinal (OSMS) often encountered Asian countries. Our aim was to compare the clinical features, neuropsychological profile cytokine/chemokine levels patients with conventional MS (CMS) presenting predominantly cord nerve attacks (MS-SCON).Design: Cross-sectional study.Setting: Outpatient Clinic.Participants: Fourteen MS-SCON...

10.1080/10790268.2019.1666238 article EN Journal of Spinal Cord Medicine 2019-09-26

Prolactin has been discussed as a factor likely to play mediating role in multiple sclerosis (MS). Our aim was investigate the possible association between prolactin production and clinical features of autoimmune demyelinating central nervous system disorders.Serum levels 255 MS patients, 19 neuromyelitis optica (NMO) 15 clinically isolated syndrome (CIS) 240 healthy controls were measured by heterogeneous sandwich magnetic separation assay.MS NMO cohorts had significantly higher number...

10.5152/npa.2016.16979 article EN Nöro Psikiyatri Arşivi 2016-03-23

AbstractAs a complication of hydatid cyst disease the liver, bronchobiliary fistula is rare condition and manifests as bilioptysis. We report case 34 year-old man with echinococcosis liver who developed which manifested chronic cough bile stained sputum. A chest X-ray showed an unilateral infiltrate in costodiaphragmatic angle. Bronchoscopy revealed filling right basal bronchi. Magnetic resonance cystography that hepatic ducts communicated pleural space. Percutaneous transhepatic drainage...

10.1080/00015458.2002.11679297 article EN Acta Chirurgica Belgica 2002-01-01

<b><i>Objective:</i></b> This study was conducted to identify a biomarker for multiple sclerosis (MS) that can be used as predictor of relapse and disability. <b><i>Materials Methods:</i></b> Sera 26 consecutive relapsing-remitting MS (RRMS) patients were screened switch-associated protein 70 (SWAP-70) antibody, which previously identified by macroarray. The serum levels several cytokines, chemokines soluble adhesion molecules related attacks...

10.1159/000358221 article EN cc-by-nc Medical Principles and Practice 2014-01-01

Inflammatory bowel disease is a chronic, recurrent disorder that involves multiple organ systems. Polyneuropathy the most common neurological manifestation. The aim of present study was to investigate relationship between polyneuropathy and inflammatory disease.The included 40 patients with infl ammatory (20 ulcerative colitis 20 Crohn's disease) 24 healthy controls. had no clinical signs or symptoms polyneuropathy. Nerve conduction studies were performed using an electroneuromyography...

10.5009/gnl.2011.5.1.57 article EN cc-by-nc Gut and Liver 2011-03-25

Background: Caudal epidural block (CEB) has long been used as a standard method for pain control in pediatric surgery. Erector spinae plane (ESPB) is newer technique that attracted attention its potential to provide analgesia children. Aim: The aim of this study was compare and evaluate the effectiveness ESPB caudal on postoperative patients who underwent unilateral inguinal hernia Methods: This prospective, randomized trial conducted with total 60 patients, aged 1–8 years, ASA I–II group....

10.4103/njcp.njcp_408_24 article EN Nigerian Journal of Clinical Practice 2024-10-01

DOI : 10.17681/hsp.424602 Purpose: Cancer is one of the most important health problems nowadays. With these features disease; frequent occurance, being preventable, high mortality and treated with early diagnosis, cancer a matter public health. Aim this research, to test lifestyle habits professionals, whether prevent occurance or not determine their knowledge, attitudes behaviors about diagnosis. Materials Methods: This descriptive study has been made by 500 people meet all conditions among...

10.17681/hsp.424602 article EN Sağlık Bilimleri ve Meslekleri Dergisi 2019-03-14
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