A5101539064- Influenza Virus Research Studies
- Respiratory viral infections research
- SARS-CoV-2 and COVID-19 Research
- Vaccine Coverage and Hesitancy
- Bone and Joint Diseases
- Viral gastroenteritis research and epidemiology
- Parkinson's Disease Mechanisms and Treatments
- Hip disorders and treatments
- Pneumonia and Respiratory Infections
- Bone health and treatments
- Immune Response and Inflammation
- Inflammatory Bowel Disease
- Mercury impact and mitigation studies
- Hepatitis Viruses Studies and Epidemiology
- Nutritional Studies and Diet
- Asthma and respiratory diseases
- COVID-19 epidemiological studies
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Immunotherapy and Immune Responses
- Bacterial Infections and Vaccines
- Spine and Intervertebral Disc Pathology
- COVID-19 Clinical Research Studies
- Peripheral Neuropathies and Disorders
- Obesity, Physical Activity, Diet
SOUSEIKAI Global Clinical Research Center
2017-2025
Osaka City University
2012-2022
College of Healthcare Management
2016-2021
LTT Bio-Pharma (Japan)
2015-2021
Tsukuba University of Technology
2020
Fukuoka Higashi Medical Center
2017-2019
Osaka City University Hospital
2004-2015
Faculty (United Kingdom)
2014-2015
Kagoshima University Hospital
2013
Fondazione Audiologica Varese
2005
To investigate the association of alcohol intake, cigarette smoking, occupation, and other factors with development idiopathic osteonecrosis femoral head, a nationwide multicenter case-control study was conducted in Japan during 1988-1990, comparing 118 cases no history systemic corticosteroid use 236 controls matched for sex, age, ethnicity, clinic, date initial examination. The risks developing head necrosis associated potential risk were estimated by adjusted relative odds obtained...
In Brief Study Design. Prospective multicenter study. Objective. To identify radiographic or magnetic resonance (MR) images of fresh vertebral fractures that can predict a high risk for delayed union nonunion osteoporotic (OVFs). Summary Background Data. Vertebral body are the most common in osteoporosis patients. Conservative treatments typically chosen OVFs, and associated back pain generally subsides within several weeks with residual persistent deformity body. some patients, OVF healing...
Based on the unique characteristics of influenza, concept "monitoring" influenza vaccine effectiveness (VE) across seasons using same observational study design has been developed. In recent years, there a growing number VE reports test-negative design, which can minimize both misclassification diseases and confounding by health care-seeking behavior. Although designs offer considerable advantages, are some concerns that widespread use without knowledge basic principles epidemiology could...
Advances in transplantation technology have brought about great benefits to patients suffering from organ failure, but the problem still remains of complications induced by steroids used for post-transplant immunosuppression. Among side-effects caused steroids, non-traumatic osteonecrosis femoral head (ONF) constitutes a serious problem. The same protocol steroid administration induces ONF some patients, not others, indicating presence individual difference sensitivity. We hypothesized that...
The project to develop a new Japanese Orthopaedic Association (JOA) score rating system for low back disorders, the JOA Back Pain Evaluation Questionnaire (JOABPEQ), is currently in progress. Part 1 of study selected 25 "candidate" items use on JOABPEQ. purpose this current 2 was verify reliability questionnaire. A total 161 patients with low-back disorders any type participated study. Each patient interviewed twice at an interval weeks using same questionnaire evaluated by determining...
The Japanese Orthopaedic Association decided to revise the JOA score for low back pain and develop a new outcome measure. In February 2002, first survey was performed with preliminary questionnaire consisting of 60 evaluation items. Based on findings that survey, 25 items were selected draft Back Pain Evaluation Questionnaire (JOABPEQ). second confirm reliability questionnaire. This article further evaluates validity this establishes measurement scale. subjects study consisted 355 patients...
Background. An ecological analysis found that the docosahexaenoic acid content in mother's milk and seafood intake were inversely correlated with postpartum depression. This prospective study investigated relationship of consumption selected high-fat foods specific types fatty acids risk Method. The subjects 865 Japanese women. Dietary data obtained from a self-administered diet history questionnaire during pregnancy. Edinburgh Postnatal Depression Scale (EPDS) was used for evaluation...
Increased homocysteine levels might accelerate dopaminergic cell death in Parkinson's disease (PD) through neurotoxic effects; thus, increasing intake of B vitamins involved the regulation metabolism decrease risk PD decreasing plasma homocysteine. However, epidemiological evidence for association dietary with is sparse, particularly non-Western populations. We conducted a hospital-based case–control study Japan to examine associations between folate, vitamin 6 , 12 and riboflavin PD....
Abstract Objectives There have been no nationwide epidemiological studies of idiopathic normal pressure hydrocephalus ( iNPH ) in Japan. Therefore, a epidemiologic survey was performed to determine the number cases and clinical characteristics by sex diagnostic level. Methods The first examined numbers that met criteria those who underwent shunt operations 2012. second gathered patients' details clarify their background characteristics. Results estimated meeting 2012 12,900, with 6,700...
Background and aimsAppropriate influenza vaccination is important for patients with inflammatory bowel disease under immunosuppressive therapy. The purpose of this study was to evaluate the influence therapy on immune response trivalent vaccine in adult disease.
An outcome measure to evaluate the neurological function of cervical myelopathy was proposed by Japanese Orthopaedic Association in 1975 (JOA score), and has been widely used Japan. However, JOA score does not include patients' satisfaction, disability, handicaps, or general health, which can be affected myelopathy. The purpose this study develop a new for patients with This conducted eight university hospitals their affiliated from February May 2002. questionnaire included 77 items....
Background Up to now a malaria vaccine remains elusive. The Plasmodium falciparum serine repeat antigen-5 formulated with aluminum hydroxyl gel (BK-SE36) is blood-stage candidate that has undergone phase 1a trial in malaria-naive Japanese adults. We have assessed the safety and immunogenicity of BK-SE36 endemic area Northern Uganda. Methods performed two-stage, randomized, single-blinded, placebo-controlled 1b (Current Controlled trials ISRCTN71619711). A computer-generated sequence...
Background. Pregnant women are a high-risk group for influenza-associated complications and hospitalizations.
Abstract Background and Aim The prevalence of ulcerative colitis (UC) has been increasing in Japan. Trace elements, such as iron, zinc, magnesium, copper, can cause digestive symptoms where there is a deficiency or excess. We focused on the dietary intake trace elements their associations with UC development. Methods A multicenter, hospital‐based case–control study was conducted Cases were 127 newly diagnosed patients, 171 age‐matched sex‐matched hospital controls recruited. considered that...
The Japanese government approved COVID-19 vaccine booster doses in November 2021. However, intentions and readiness for vaccines among the general population were unknown. This survey measured vaccination. Among 6172 participants (53.2% female), 4832 (78.3%) accepted doses; 415 (6.7%) hesitated. Vaccination intention was associated with higher age, marital status, having children, underlying diseases, social norms. To evaluate vaccination, seven component (7C) vaccination scale employed,...
Aim Elderly adults are at higher risk for severe COVID‐19 infection. This multicenter, prospective cohort study assessed immunogenicity after vaccinations in elderly residents compared with staff geriatric intermediate care facilities. Predictors of lower antibody titers were also examined. Methods Fifty‐four and 117 who had received three doses the mRNA vaccine between March 2021 September 2022 included. Anti‐receptor binding domain measured 3–4 weeks 6 months vaccinations. Adjusted...