A5045988054- SARS-CoV-2 and COVID-19 Research
- COVID-19 epidemiological studies
- COVID-19 Clinical Research Studies
- Animal Virus Infections Studies
- Respiratory viral infections research
- Long-Term Effects of COVID-19
- Heparin-Induced Thrombocytopenia and Thrombosis
- Immune responses and vaccinations
- Immunodeficiency and Autoimmune Disorders
- Influenza Virus Research Studies
- Bacterial Infections and Vaccines
- Vaccine Coverage and Hesitancy
Tokyo Metropolitan University
2022-2025
Osaka Metropolitan University
2022-2025
Osaka City University
2023
Aim Elderly adults are at higher risk for severe COVID‐19 infection. This multicenter, prospective cohort study assessed immunogenicity after vaccinations in elderly residents compared with staff geriatric intermediate care facilities. Predictors of lower antibody titers were also examined. Methods Fifty‐four and 117 who had received three doses the mRNA vaccine between March 2021 September 2022 included. Anti‐receptor binding domain measured 3–4 weeks 6 months vaccinations. Adjusted...
Although several assays are used to measure anti-receptor-binding domain (RBD) antibodies induced after severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) vaccination, the not fully comparable in practice. This study evaluated immunogenicity of BNT162b2 mRNA vaccine healthy adults using two immunoassays. prospective cohort included SARS-CoV-2-naïve adults, predominantly healthcare workers, aged 20–64 years, who received doses between March and May 2021. Blood samples were collected...
Abstract To evaluate the antibody response following initial four doses of mRNA vaccines (BNT162b2 or mRNA-1273) in SARS-CoV-2-naïve healthy adults and investigate factors influencing titer increases, this prospective cohort study was conducted Japan from March 2021. The included participants who received either 1st 2nd (n = 467), 3rd dose 157), 4th 89). Blood samples were collected before up to 6 months after each dose, anti-receptor-binding domain levels measured. Multivariate analysis...
Elucidating the epidemiological picture in early phase of a pandemic is crucial to strengthening preparedness and public health responses future emerging infectious diseases. Using data from "Osaka Prefectural Novel Coronavirus Response Status Management System," we evaluated factors associated with mortality among patients novel coronavirus disease 2019 (COVID-19) Osaka Prefecture, Japan.
Abstract Background The association between inactivated influenza vaccination and viral load in young children remains unclear. Methods During the 2013/2014 to 2017/2018 seasons Japan, under 6 years of age with pre‐defined influenza‐like illness influenza‐positive status by real‐time RT‐PCR were recruited at pediatric clinics for this observational study. Influenza was measured most predominant subtype/lineage each season. Using median dichotomized as an outcome, a multilevel logistic...
To evaluate antibody responses against the primary series of vaccination severe acute respiratory syndrome coronavirus-2 [SARS-CoV-2] vaccines in staff and residents Japanese geriatric intermediate care facilities. All subjects (159 96 residents) received two doses BNT162b2 mRNA vaccine 3 weeks apart. Baseline data subject were collected using a structured form. Serum samples three times: before vaccination, after first dose, 4 second anti-receptor binding domain spike protein SARS-CoV-2...
Background: To evaluate antibody responses against the primary series of vaccination severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) vaccines in staff and residents Japanese geriatric intermediate care facilities.Methods: All subjects (159 96 residents) received two doses BNT162b2 mRNA vaccine 3 weeks apart. Baseline data subject were collected using a structured form. Serum samples three times: before vaccination, after first dose, 4 second anti-receptor binding domain spike...