A5021240791- Helicobacter pylori-related gastroenterology studies
- Autoimmune Bullous Skin Diseases
- Pancreatic and Hepatic Oncology Research
- Urticaria and Related Conditions
- Drug-Induced Adverse Reactions
- Eosinophilic Esophagitis
- Ocular Diseases and Behçet’s Syndrome
- Gastric Cancer Management and Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Vasculitis and related conditions
- Cancer Risks and Factors
- Retinal and Optic Conditions
- Cerebrospinal fluid and hydrocephalus
- Colorectal Cancer Screening and Detection
- Skin and Cellular Biology Research
- Health disparities and outcomes
- Gastroesophageal reflux and treatments
- Contact Dermatitis and Allergies
- Nutritional Studies and Diet
- Growth Hormone and Insulin-like Growth Factors
- Vaccine Coverage and Hesitancy
- Systemic Lupus Erythematosus Research
- Tea Polyphenols and Effects
- Phytoestrogen effects and research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
Juntendo University
2015-2024
Juntendo University Hospital
2009
Radiation Effects Research Foundation
2009
Chiba Cancer Center
2009
Abstract Generalized pustular psoriasis ( GPP ) is a rare disease characterized by recurrent fever and systemic flushing accompanied extensive sterile pustules. The committee of the guidelines was founded as collaborative project between Japanese Dermatological Association Study Group for Rare Intractable Skin Diseases under Ministry Health, Labour, Welfare Research Project on Overcoming Diseases. aim to provide current information aid in treatment patients with Japan. Its contents include...
Abstract Drug‐induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms ( DIHS / DRESS ) is a severe adverse drug caused by specific drug. It characterized visceral organ involvement reactivation of various human herpesviruses. Although sporadic reports have documented certain conditions that appear after the resolution , little information available on sequelae in large patient population. The A sian Research Committee Severe Cutaneous Adverse Reactions,...
Abstract Background : Helicobacter pylori is a major cause of various gastroduodenal diseases. Some risk factors related to H. infection have been reported; however, studies on the relationship between and smoking or drinking habits given conflicting results. In present study, these relationships were investigated by collecting sera information from 8837 subjects. Methods Serum immunoglobulin G antibody was measured an enzyme‐linked immunoassay. addition sex age, collected questionnaire....
BACKGROUND: A self-administered questionnaire on dietary habits used in the JACC Study contained a 40-item food frequency (FFQ). Although more than 110 thousand subjects enrolled and responded to FFQ, no validation study has been conducted date.METHODS: Eighty-five volunteers among cohort members completed 2 FFQs (FFQs 1&2) 12-day weighed records (WDR). The interval between two was one year. During year, carried out 3-consecutive-day WDR each season. We tested reproducibility by using FFQs....
Abstract Objectives There have been no nationwide epidemiological studies of idiopathic normal pressure hydrocephalus ( iNPH ) in Japan. Therefore, a epidemiologic survey was performed to determine the number cases and clinical characteristics by sex diagnostic level. Methods The first examined numbers that met criteria those who underwent shunt operations 2012. second gathered patients' details clarify their background characteristics. Results estimated meeting 2012 12,900, with 6,700...
This report aimed to scrutinize the prevalence of Behçet's disease (BD)-related clinical manifestations based on age- and sex-specific subgroups using a Japanese nationwide registration database.The database newly registered BD was obtained from Ministry Health, Labour Welfare. Patients who met International Criteria for Disease were selected analysed.Among 6627 cases, 2651 (40.0%) men 3976 (60.0%) women with median age 39 years (interquartile range: 31-50 years). Ocular lesion more common...
Abstract The pemphigoid group is a category of autoimmune subepidermal blistering diseases in which autoantibodies deposit linearly at the epidermal basement membrane zone ( BMZ ). main subtypes mediated by immunoglobulin G are bullous BP ), mucous MMP ) and epidermolysis bullosa acquisita EBA To establish first guidelines approved Japanese Dermatological Association for management diseases, Committee Guidelines Management Pemphigoid Diseases (Including was founded as part Study Group Rare...
Abstract Background We hypothesized that Behçet’s disease (BD) consists of several clinical subtypes with different severity, resulting in heterogeneity the disease. Here, we conducted a study to identify clusters BD. Methods A total 657 patients registered Yokohama City University (YCU) regional BD registry between 1990 and 2018, as well 6754 who were initially Japanese Ministry Health, Labour Welfare (MHLW) database 2003 2014, investigated. The YCU data regarding manifestations BD, human...
Abstract We evaluated the associations of such lifestyle factors as alcohol drinking, coffee consumption and medical history with risk death from pancreatic cancer in a large‐scale prospective cohort study [the Japan Collaborative Cohort Study for Evaluation Cancer Risk (JACC study)] Japan. Subjects were 110,792 (46,465 men 64,327 women) inhabitants who enrolled 45 areas throughout At baseline, self‐administered questionnaire was used to obtain information on history. Cox proportional hazard...
It is unclear whether body mass index (BMI) and physical activity are associated with the risk of pancreatic cancer in Asian populations. We examined these associations Japanese Collaborative Cohort Study for Evaluation Cancer Risk. Our cohort study included 110,792 men women at enrollment (1988-1990). Data on height, weight (at baseline age 20 years) were obtained from a questionnaire. Cox proportional hazards models used to estimate relative risks mortality. observed total 402 deaths...
Abstract Recent epidemiological studies have shown that high serum levels of insulin‐like growth factor‐I (IGF‐I) are associated with an increased risk lung, colon, breast and prostate cancer. Since very few addressed the role IGF‐I in development pancreatic cancer, we conducted a nested case‐control study to examine this association. The analysis involved 69 case subjects who died from cancer during follow‐up period study, 207 control matched for sex, age(±1 year) area, selected randomly...
The purpose of this study was to assess how changes from different baselines activities daily living (ADL) can be explained by marital status, arrangement and healthcare.Using data the Chinese Longitudinal Health Longevity Study conducted in 2002 2005, 8,099 surviving 3,822 deceased elderly aged 65 years over were evaluated using multinomial logistic regression.After adjusting for demographic, socioeconomic health factors, who either married or alone less likely encounter ADL decline...
Gallbladder cancer is a rare with poor prognosis, and few risk factors have been identified to date. This prospective study was conducted evaluate the association of cigarette smoking alcohol consumption gallbladder death. A baseline survey in 45 areas throughout Japan from 1988 1990 using self-administered questionnaire, total 113,496 participants (65,740 women) aged 40-89 years at entry were followed for 15 years. During follow-up period, 165 deaths (95 observed. Among women, hazard ratio...
This study aimed to describe the epidemiologic characteristics of microscopic polyangiitis (MPA) and granulomatosis with (GPA) in Japan.
We assessed the association between infection with CagA-positive and -negative Helicobacter pylori risk of gastric cancer in young adults.CagA IgG antibodies were measured sera subjects participating a case-control study Japan. The 103 patients <40 yr age, 100 inpatients benign diseases, 101 screenees younger than age 43 yr.Compared H. pylori-negative/CagA-negative (H. pylori-/CagA-) group, both pylori-positive/CagA-negative pylori+/CagA-) group pylori-positive/CagA-positive pylori+/CagA+)...
Abstract Abstract: Few epidemiological studies have examined associations between diet and pancreatic cancer in Japan. In the Japan Collaborative Cohort Study for Evaluation of Cancer Risk, we evaluated relationship dietary factors, including meat, vegetable, fruit intake, risk deaths. Among original cohort established 1988 1990, 46,465 men 64,327 women aged 40–79 yr were followed-up through December 31,1999. During 1,042,608 person-years follow-up, documented 300 deaths from cancer. A...
Objective: Green tea polyphenols have been shown to inhibit tumor growth in animal and vitro studies. We examined the relationship between green consumption risk of death from pancreatic cancer a large Japanese cohort. Methods: At baseline (1988-1990), study participants reported frequency amount during past year. They were followed-up for mortality until December 31, 2003. Relative 95% confidence intervals calculated Cox proportional hazard models. Results: During an average follow-up 13...