A5032543152- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Acute Myocardial Infarction Research
- Infective Endocarditis Diagnosis and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Aortic Disease and Treatment Approaches
- Cardiac and Coronary Surgery Techniques
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Function and Risk Factors
- Venous Thromboembolism Diagnosis and Management
- Coronary Artery Anomalies
- Lipoproteins and Cardiovascular Health
- Cardiac, Anesthesia and Surgical Outcomes
- Atrial Fibrillation Management and Outcomes
- Cardiac Structural Anomalies and Repair
- Cardiac pacing and defibrillation studies
- Heart Failure Treatment and Management
- Chemical Thermodynamics and Molecular Structure
- Hemodynamic Monitoring and Therapy
- Congenital Heart Disease Studies
- Cardiovascular Effects of Exercise
- Teratomas and Epidermoid Cysts
- Cardiomyopathy and Myosin Studies
- Gout, Hyperuricemia, Uric Acid
Istituto Clinico Sant'Ambrogio
2020-2024
Onze Lieve Vrouwziekenhuis Hospital
2014-2023
Istituto Ortopedico Galeazzi
2023
University of Naples Federico II
1998-2022
Centro de Investigación en Red en Enfermedades Cardiovasculares
2022
Universidad de Valladolid
2022
Federico II University Hospital
2004-2019
Radboud University Nijmegen
2017-2018
Eindhoven University of Technology
2017-2018
Catharina Ziekenhuis
2017-2018
Background— Fractional flow reserve (FFR) measurement of intermediate coronary stenoses is recommended by guidelines when demonstration ischemia noninvasive testing unavailable. The study aims to evaluate the penetration this recommendation into current thinking about revascularization strategies for stable artery disease. Methods and Results— International Survey on Interventional Strategy was conducted via a web-based platform. First, participants’ experiences in interventional cardiology...
Background— The fractional flow reserve (FFR) value of 0.75 has been validated against ischemic testing, whereas the FFR 0.80 widely accepted to guide clinical decision making. However, revascularization when is 0.76 0.80, within so-called gray zone, still debatable. Methods and Results— From February 1997 June 2013, all patients with single-segment disease an zone or 2 neighboring strata (0.70–0.75 0.81–0.85) were included. Study end points consisted major adverse cardiovascular events...
Background— The principle of continuous thermodilution can be used to calculate absolute coronary blood flow and microvascular resistance (R). aim the study is explore safety, feasibility, reproducibility R measurements as measured by in humans. Methods Results— Absolute calculated infusing saline at room temperature through a dedicated monorail catheter. it enters vessel, mixed distal part pressure were pressure/temperature sensor-tipped guidewire. feasibility safety method tested 135...
Background— Fractional flow reserve (FFR), an index of the hemodynamic severity coronary stenoses, is derived from invasive measurements and requires a pressure-monitoring guidewire hyperemic stimulus. Angiography-derived FFR (FFR angio ) may have several advantages. The aim this study to assess diagnostic performance interobserver reproducibility in patients with stable artery disease. Methods Results— computational method based on rapid analysis for assessment FFR. uses patient’s data...
During thermodilution-based assessment of volumetric coronary blood flow, we observed that intracoronary infusion saline increased flow. This study aims to quantify the extent and unravel mechanisms saline-induced hyperemia.Thirty-three patients were studied; in 24 patients, Doppler flow velocity measurements performed at rest, after adenosine, during increasing rates room temperature through a dedicated catheter with 4 lateral side holes. In 9 global longitudinal strain propagation assessed...
The correlation between angiographic assessment of coronary stenoses and fractional flow reserve (FFR) is weak. Whether how risk factors impact the diagnostic accuracy angiography unknown. We sought to evaluate by visual estimate quantitative when compared with FFR influence (RF) on this accuracy.In 1382 (1104 patients), percent diameter stenosis estimation (DSVE) (DSQCA) was FFR. Patients were divided into 4 subgroups, according presence RFs, relationship DSVE, DSQCA, analyzed. Overall,...
Transcatheter aortic valve replacement (TAVR) is an effective treatment option for patients with severe, symptomatic AS, regardless of the transcatheter heart (THV) implanted. Prior studies demonstrated a higher device success lower paravalvular leak (PVL) using balloon-expandable (BE) Sapien/XT THV vs. self-expanding (SE) THV. However, few data are available on performance novel BE
True coronary bifurcation lesions (CBL) represent a challenging scenario for percutaneous interventions (PCI), and are associated with higher risk of target lesion failure (TLF), particularly when two stents implanted. A hybrid strategy combining drug-eluting stent (DES) in the main branch, drug-coated balloon side branch may improve outcomes by reducing total length while maintaining an effective anti-prolipherative action. In this sub-study HYPER trial, 50 patients true CBL were treated...
Fractional flow reserve (FFR) has never been investigated in patients with reduced ejection fraction and associated coronary artery disease (CAD). We evaluated the impact of FFR on management strategies these related outcomes.From 2002 to 2010, all consecutive left ventricular (LVEF) ≤50% undergoing angiography ≥1 intermediate stenosis [diameter (DS)% 50-70%] treated based (Angiography-guided group) or according (FFR-guided were screened for inclusion. In FFR-guided group, 433 matched 866...
De novo diffuse coronary artery disease (CAD) is a challenging scenario in interventional cardiology with limited treatment option, beside stent implantation. In this context, hybrid approach, combining the use of drug-eluting (DES) and drug-coated balloon (DCB) to treat different segments same lesion (e.g. long and/or true bifurcation), might be an interesting alternative strategy limit metal amount. The aim study was evaluate safety efficacy approach addressing percutaneous de CAD.