A5053680565- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Infective Endocarditis Diagnosis and Management
- Aortic aneurysm repair treatments
- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cardiac Structural Anomalies and Repair
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Cardiac, Anesthesia and Surgical Outcomes
- Intracranial Aneurysms: Treatment and Complications
- Cardiovascular and Diving-Related Complications
- Cardiovascular Function and Risk Factors
- Coronary Artery Anomalies
- Acute Myocardial Infarction Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Congenital Heart Disease Studies
- Lipoproteins and Cardiovascular Health
- Cardiac tumors and thrombi
- Antiplatelet Therapy and Cardiovascular Diseases
- Venous Thromboembolism Diagnosis and Management
- Traumatic Ocular and Foreign Body Injuries
- Cardiac Arrhythmias and Treatments
- Reservoir Engineering and Simulation Methods
- Aortic Thrombus and Embolism
IRCCS Policlinico San Donato
2018-2024
Society of Interventional Radiology
2020
University of Insubria
2014-2018
West German Heart and Vascular Center Essen
2015-2017
Ospedale di Circolo e Fondazione Macchi
2014-2016
Riverbank Local Redevelopment Authority
2015
Vita-Salute San Raffaele University
2012-2014
May Institute
2014
Istituti di Ricovero e Cura a Carattere Scientifico
2012
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2012
Myocardial infarction with non-obstructive coronary arteries (MINOCA) represents about 6-8% of patients presenting myocardial (MI), and it is associated a significant risk mortality, rehospitalisation, angina burden, high socioeconomic costs. It important to note that multiple mechanisms may be responsible for MINOCA. However, date, there are few prospective clinical trials on MINOCA the treatment these still not defined, most likely because underlying pathogenic mechanisms. The PROMISE...
Transcatheter aortic valve replacement (TAVR) in patients with bicuspid (BAV) stenosis is technically challenging and burdened by an increased risk of paravalvular regurgitation (PVR).
The European Society of Cardiology recently proposed a novel diagnostic algorithm combining the aortic dissection detection (ADD) risk score with D-dimer level assessment for detecting acute syndromes (AASs) in patients presenting chest pain. accuracy this strategy is yet to be validated.We retrospectively identified 376 pain and available on admission emergency department our institution between January 2011 May 2014. ADD was calculated using retrospective blinded chart review. A ⩽1 defined...
Accurate planning of transcatheter aortic valve implantation (TAVI) is important to minimize complications, and it requires anatomic evaluation the root (AR), commonly performed through 3D computed tomography (CT) image analysis. Currently, there no standard automated solution for this process. Two convolutional neural networks with U-Net architectures (model 1 model 2) were trained on 310 CT scans AR Model performs segmentation 2 identifies annulus sinotubular junction (STJ) contours. After...
The aim of this study was to investigate the incidence, biomarker profile and clinical impact post-implantation syndrome (PIS) after thoracic endovascular aortic repair (TEVAR) for type B acute syndromes (AASs). This retrospective included 133 patients with AASs undergoing TEVAR; PIS defined as fever >38°C, white blood cells (WBCs) >12.0/nl C-reactive protein (CRP) >10 mg/dl within 72 h TEVAR, despite negative cultures. Fibrinogen (FBG), D-dimer (D-d) interleukin 6 (IL-6) were also...
The role of D-dimer (D-d) as a diagnostic biomarker and its prognostic value in patients with intramural hematoma (IMH) or penetrating aortic ulcer (PAU) are unknown.Clinical data 231 an acute syndrome (AAS) (159 dissection [AAD], 35 IMH 37 PAU) were collected between 2010 2014. D-d was determined at admission during the hospitalization. measurements 291 admitted to chest pain unit, whom AAS ruled out, used control.Admission significantly higher AAD (12.5±11.1 mg/L) (14.8±12.2 compared PAU...
Background Acute kidney injury (AKI) after transcatheter aortic valve replacement (TAVR) is associated with increased mortality. However, it controversial whether AKI affects prognosis per se, being linked to baseline chronic disease (CKD) and bleeding complications. The aim of this study was disentangle, applying mediation analysis, the association between clinical outcome, considering CKD bleedings. Methods Results Consecutive patients undergoing TAVR were prospectively enrolled at 5...
To analyze an 11-year single-center experience of treating complicated penetrating aortic ulcer (PAU) using thoracic endovascular repair (TEVAR).This study included 63 consecutive patients (mean age 69.1±11.5 years; 40 men) with PAU (42 symptomatic, 22 rupture) who underwent TEVAR between 2002 and 2013. The PAUs were located in the arch (n=11), descending aorta (n=43), thoracoabdominal (n=9).TEVAR was performed within 14 days diagnosis 33 (52.3%) cases (19 ruptures treated immediately);...
Abstract Objectives To investigate paravalvular leak (PVL) and devices success rates according to aortic angle (AA) in patients undergoing transcatheter valve implantation (TAVI) with three new‐generation self‐expanding devices. Background The impact of on TAVI device PVL is controversial. Methods This retrospective study included 392 submitted for severe stenosis Portico, Evolut‐R Acurate‐NEO, available AA measurements at computed tomography (CT) angiography. was calculated from the...
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Background: The impact of preoperative anemia and postoperative hemoglobin (Hb) drop on the incidence acute kidney injury (AKI) after thoracic endovascular aortic repair (TEVAR) for type B syndromes (AAS) as well their prognostic value is unknown. Methods: This retrospective study included 144 patients with AAS undergoing TEVAR at our center. Preoperative was classified no/mild (Hb ≥ 12.0 g/dL in men; ≥11.3 women), moderate 10.80-11.99 10.23-11.29 severe (<10.80 <10.23 women)....
Transfemoral approach is considered the preferred route to perform transcatheter aortic valve implantation (TAVI) by most operators due low invasiveness and good outcome, as compared non-transfemoral approach. However, transfemoral access not always feasible particularly in patients with small calcific vessels. Recently, catheter-based lithoplasty has emerged a new technique based on use of circumferential pulse pressure waves disrupt plaques. This technology may help expand eligibility for...
To evaluate the prognostic impact of baseline tricuspid annular plane systolic excursion/pulmonary artery pressure (TAPSE/PASP) ratio, as an expression right ventricle-pulmonary (RV-PA) coupling, in patients with mitral regurgitation (MR) treated MitraClip.Impaired RV to PA coupling is considered a marker dysfunction.From February 2016 2020, total 165 were evaluated and stratified two groups according prespecified value TAPSE/PASP ratio ≤ 0.36.The median patients' age was 79 (men: 62.4%)....