A5030845075- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Coronary Interventions and Diagnostics
- Advanced Numerical Analysis Techniques
- Infective Endocarditis Diagnosis and Management
- Elasticity and Material Modeling
- Shape Memory Alloy Transformations
- Tribology and Lubrication Engineering
- Additive Manufacturing and 3D Printing Technologies
- Numerical methods in engineering
- Microwave Imaging and Scattering Analysis
- Ultrasound Imaging and Elastography
- Cardiovascular Function and Risk Factors
- Cellular and Composite Structures
- Fluid Dynamics and Heat Transfer
- Cardiac, Anesthesia and Surgical Outcomes
- Ultrasonics and Acoustic Wave Propagation
- Polymer composites and self-healing
- Particle Dynamics in Fluid Flows
- Composite Structure Analysis and Optimization
- Cardiac and Coronary Surgery Techniques
- Manufacturing Process and Optimization
- Dynamics and Control of Mechanical Systems
- Additive Manufacturing Materials and Processes
University of Pavia
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2025
Sapienza University of Rome
2022
IRCCS Policlinico San Donato
2012-2021
Emory University
2018
Scuola Internazionale Superiore di Studi Avanzati
2018
Additive manufacturing (or three-dimensional (3D) printing) is constantly growing as an innovative process for the production of complex-shape components. Among seven recognized 3D printing technologies, fused deposition modeling (FDM) covers a very important role, not only producing representative models, but, mainly due to development material like Peek and Ultem, also realizing structurally functional However, being FDM involving high thermal gradients, non-negligible deformations...
Abstract Numerous studies have suggested that medical image derived computational mechanics models could be developed to reduce mortality and morbidity due cardiovascular diseases by allowing for patient‐specific surgical planning customized device design. In this work, we present a novel framework designing prosthetic heart valves using parametric design platform immersogeometric fluid–structure interaction (FSI) analysis. We parameterize the leaflet geometry several key parameters. This...
Abstract Elastic geothermobarometry on inclusions is a method to determine pressure-temperature conditions of mineral growth independent chemical equilibrium. Because the difference in their elastic properties, an inclusion completely entrapped inside host will develop residual stress upon exhumation, from which one can back-calculate entrapment pressure. Current geobarometric models assume that both and are elastically isotropic have ideal geometry (the spherical isolated at center infinite...
AbstractUntil recently, heart valve failure has been treated adopting open-heart surgical techniques and cardiopulmonary bypass. However, over the last decade, minimally invasive procedures have developed to avoid high risks associated with conventional open-chest replacement techniques. Such a recent innovative procedure represents an optimal field for conducting investigations through virtual computer-based simulations: in fact, nowadays, computational engineering is widely used unravel...
Abstract The increasing use of computational fluid dynamics for simulating blood flow in clinics demands the identification appropriate patient‐specific boundary conditions customization mathematical models. These should ideally be retrieved from measurements. However, finite resolution devices as well other practical/ethical reasons prevent construction complete data sets necessary to make problems posed. Available need completed by modelling assumptions, whose impact on final solution has...
Microstructured honeycomb materials may exhibit exotic, extreme and tailorable mechanical properties, suited for innovative technological applications in a variety of modern engineering fields. The paper is focused on analysing the directional auxeticity tetrachiral materials, through analytical, numerical experimental methods. Theoretical predictions about global elastic properties have been successfully validated by performing tensile laboratory tests samples, realized with high precision...
The present paper combines an effective beam theory with a simple and accurate numerical technique opening the door to prediction of structural behavior planar beams characterized by continuous variation cross-section geometry, that in general deeply influences stress distribution and, therefore, leads non-trivial constitutive relations. Accounting for these peculiar aspects, is described mixed formulation problem represented six linear Ordinary Differential Equations (ODEs) non-constant...
Research Article| January 18, 2019 Depth of diamond formation obtained from single periclase inclusions Chiara Anzolini; Anzolini 1Department Geosciences, University Padova, Via G. Gradenigo 6, 35131 Padua, Italy Search for other works by this author on: GSW Google Scholar Fabrizio Nestola; Nestola Mattia L. Mazzucchelli; Mazzucchelli 2Department Earth and Environmental Sciences, Pavia, A. Ferrata 1, 27100 Matteo Alvaro; Alvaro Paolo Nimis; Nimis Andrea Gianese; Gianese Simone Morganti;...
Mineral inclusions entrapped in other minerals may record the local stresses at moment of their entrapment deep Earth. When rocks are exhumed to surface Earth, residual and strains still be preserved inclusion. If measured interpreted correctly through elastic geobarometry, they give us invaluable information on pressures (P) temperatures (T) metamorphism. Current estimates P T rely simplified models that assumes inclusion is spherical embedded an infinite host, properties isotropic. We...
SUMMARY Finite element analysis is nowadays a well‐assessed technique to investigate the impact of stenting on vessel wall and, given rapid progression both medical imaging techniques and computational methods, challenge using simulation carotid artery as procedure planning tool support clinical practice can be approached. Within this context, present study investigates stent apposition anatomy by means patient‐specific finite analysis. In particular, we focus influence constitutive model...
Abstract Objective In recent decades patients referred for cardiac surgery have dramatically changed. Increase in patient‘s age and concomitant comorbidities, led to significant more complexcases. order optimize decision making process postoperative outcomes, the application of modern engineering techniques medical field is becoming frequent will probably be mandatory near future. this study we report a clinical case emblematic multi step co–operation our division with department University....
AbstractIn some cases of aortic valve leaflet disease, the implant a stentless biological prosthesis represents an excellent option for replacement (AVR). In particular, if compared with mechanical valves, it provides more physiological haemodynamic performance and reduced thrombogeneticity, avoiding use anticoagulants. The clinical outcomes AVR are strongly dependent on appropriate choice both size technique, which is, at present, strictly related to surgeon's experience skill. This...
Transcatheter aortic valve replacement has proved its safety and effectiveness in intermediate- to high-risk inoperable patients with severe stenosis. However, despite current guideline recommendations, the use of transcatheter (TAVR) treat stenosis caused by degenerative leaflet thickening calcification not been widely adopted low-risk patients. This reluctance among both cardiac surgeons cardiologists could be due concerns regarding clinical subclinical thrombosis. Stent performance...