A5019202358- Aortic Disease and Treatment Approaches
- Cardiac Valve Diseases and Treatments
- Aortic aneurysm repair treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Hip and Femur Fractures
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Cardiac electrophysiology and arrhythmias
- Cardiac Health and Mental Health
- Cardiac Structural Anomalies and Repair
- Congenital Heart Disease Studies
- Cardiac Arrhythmias and Treatments
- Acute Myocardial Infarction Research
- Cardiac Arrest and Resuscitation
- Cardiac Imaging and Diagnostics
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Connective tissue disorders research
- Cardiovascular Health and Risk Factors
- Cardiovascular Effects of Exercise
- Ion channel regulation and function
- Chronic Disease Management Strategies
- Cardiovascular Issues in Pregnancy
- Cardiomyopathy and Myosin Studies
- Cardiac and Coronary Surgery Techniques
University of Michigan
2015-2024
Michigan Medicine
2009-2022
Vall d'Hebron Hospital Universitari
2011-2020
Hadassah Medical Center
2012-2020
Technical University of Munich
2018-2019
Methodist Hospital
2018
Montgomery College
2012-2018
University of Washington
2017
Brigham and Women's Hospital
2011-2016
Massachusetts General Hospital
2011-2016
Background— In 2010, the American Heart Association and College of Cardiology released guidelines for diagnosis management patients with thoracic aortic disease, which identified high-risk clinical features to assist in early detection acute dissection. The sensitivity these risk markers has not been validated. Methods Results— We examined enrolled International Registry Acute Aortic Dissection from 1996 2009. number confirmed dissection who presented 1 or more 12 proposed was determined. An...
Background— In acute aortic dissection, delays exist between presentation and diagnosis and, once diagnosed, definitive treatment. This study aimed to define the variables associated with these delays. Methods Results— Acute dissection patients enrolled in International Registry of Aortic Dissection (IRAD) 1996 January 2007 were evaluated for factors contributing surgery. Multiple linear regression was performed determine relative delay time ratios (DTRs) individual correlates. The median...
Early data revealed a mortality rate of 1% to 2% per hour for type A acute aortic dissection (TAAAD) during the initial 48 hours. Despite advances in diagnostic testing and treatment, this continues be cited because lack contemporary characterizing early effect timely surgery.To examine rates patients with TAAAD era.This cohort study examined International Registry Acute Aortic Dissection between 1996 2018. Patients were grouped according mode their intended surgical or medical.Surgical...
Acute aortic intramural hematoma (IMH) is an important subgroup of dissection, and controversy surrounds appropriate management.Patients with acute syndromes in the International Registry Aortic Dissection (1996-2011) were evaluated to examine differences between patients (based on initial imaging test) IMH or classic dissection (AD). Of 2830 patients, 178 had (64 type A [42%], 90 B [58%], 24 arch). Patients older presented similar symptoms, such as severe pain. less likely present...
Background— Stroke is a highly dreaded complication of type A acute aortic dissection (TAAAD). However, little data exist on its incidence and association with prognosis. Methods Results— We evaluated 2202 patients TAAAD (mean age 62±14 years, 1487 [67.5%] men) from the International Registry Acute Aortic Dissection to determine prognostic impact stroke in TAAAD. was present at arrival 132 (6.0%) These were older (65±12 versus 62±15 years; P =0.002) more likely have hypertension (86% 71%;...
This investigation was designed to determine whether the rate of isovolumic left ventricular pressure decline is affected by load in man. Fourteen patients were instrumented with micromanometer and right atrial pacing catheters maintain a constant heart during control conditions infusion methoxamine or nitroprusside. The relaxation period defined as time from peak (-)dP/dt 5 mm Hg above end-diastolic following beat. calculated constants (Tau) linear regression natural log vs (Tln)...
Currently no research exists assessing lifestyle modifications and emotional state of acute aortic dissection (AAD) survivors. We sought to assess activity, mental health, sexual function in AAD survivors.Physical activity will decrease survivors compared pre-dissection. Incidence anxiety depression be significant after AAD.A cross sectional survey was mailed 197 subjects from a single academic medical center (part larger IRAD database). Subjects were ≥18 years age surviving type A or B...
Between January 1996 and May 2017, the International Registry on Acute Aortic Dissections has collected information a total of 6,424 consecutive patients with acute aortic dissection, including 258 individuals diagnosis Marfan syndrome. Patients syndrome presented at significantly younger age compared to without (38.2±13.2 vs. 63.0±14.0 years; P<0.001) in general had fewer comorbidities, although they more frequently known aneurysm history prior cardiac surgery. We noted larger diameters...
Improved medical care after initial aortic dissection (AD) has led to increased survivorship and a population of individuals at risk for further cardiovascular events, including recurrent AD. Reports describing ADs have been restricted small numbers patients from single institutions. We used the IRAD (International Registry Acute Aortic Dissection) database examine clinical profiles outcomes with AD.We identified 204 enrolled in For primary analysis, patient characteristics, interventions,...