Sandra Lauck
A5024773710- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Aortic Disease and Treatment Approaches
- Cardiac Health and Mental Health
- Cardiac pacing and defibrillation studies
- Cardiac Imaging and Diagnostics
- Health Systems, Economic Evaluations, Quality of Life
- Cardiovascular Function and Risk Factors
- Frailty in Older Adults
- Antiplatelet Therapy and Cardiovascular Diseases
- Atrial Fibrillation Management and Outcomes
- Cardiac Structural Anomalies and Repair
- Nutrition and Health in Aging
- Coronary Interventions and Diagnostics
- Hip and Femur Fractures
- Acute Myocardial Infarction Research
- Health Policy Implementation Science
- Clinical practice guidelines implementation
- Venous Thromboembolism Diagnosis and Management
- Healthcare Policy and Management
- Cardiac Arrhythmias and Treatments
- Patient-Provider Communication in Healthcare
- Health Sciences Research and Education
- Heart Failure Treatment and Management
University of British Columbia
2016-2025
St. Paul's Hospital
2015-2024
St. Paul's Hospital
2013-2024
Vancouver General Hospital
2015-2024
St. Paul's Co-educational College
2024
Valve (United States)
2016-2024
Heart and Stroke Foundation
2023
Providence Health Care
2012-2021
Hackensack University Medical Center
2021
Clinical Research Management
2019
Guidelines recommend a trial of one or more antiarrhythmic drugs before catheter ablation is considered in patients with atrial fibrillation. However, first-line may be effective maintaining sinus rhythm. We randomly assigned 303 symptomatic, paroxysmal, untreated fibrillation to undergo cryothermy balloon receive drug therapy for initial rhythm control. All the received an implantable cardiac monitoring device detect tachyarrhythmia. The follow-up period was 12 months. primary end point...
Background— Although short- and medium-term outcomes after transcatheter aortic valve implantation are encouraging, long-term data on function clinical limited. Methods Results— Consecutive high-risk patients who had been declined as surgical candidates because of comorbidities but underwent successful with a balloon-expandable between January 2005 December 2006 survived past 30 days were assessed. Clinical, echocardiographic, computed tomographic follow-up examinations performed. Seventy...
Atrial fibrillation is a chronic, progressive disorder, and persistent forms of atrial are associated with increased risks thromboembolism heart failure. Catheter ablation as initial therapy may modify the pathogenic mechanism alter progression to fibrillation.
We describe the development, implementation, and evaluation of a standardized clinical pathway to facilitate safe discharge home at earliest time after transfemoral transcatheter aortic valve replacement. Between May 2012 October 2014, Heart Team developed suited unique requirements replacement in contemporary practice. The components included risk-stratified minimalist periprocedure approach, postprocedure care with early mobilization reconditioning, criteria-driven home. Our aim was reduce...
Background: Open surgical closure and small-bore suture-based preclosure devices have limitations when used for transcatheter aortic valve replacement, percutaneous endovascular abdominal aneurysm repair, or thoracic repair. The MANTA vascular device is a novel collagen-based technology designed to close large bore arteriotomies created by with an outer diameter ranging from 12F 25F. In this study, we determined the safety effectiveness of device. Methods Results: A prospective, single arm,...
We sought to assess the impact of low-profile sheaths on vascular complications during transfemoral transcatheter aortic valve replacement (TAVR).This retrospective single-study population comprised a total 375 consecutive patients with severe stenosis who underwent TAVR from January 2008 November 2012. Of these, 204 (54.4%) using 14-18 Fr (low-profile sheath [LPS] group), and 171 (45.6%) 19-24 (high-profile [HPS] group). Vascular bleeding were defined according VARC-2 definitions....
Background: Older adults undergoing aortic valve replacement (AVR) are at risk for malnutrition. The association between preprocedural nutritional status and midterm mortality has yet to be determined. Methods: FRAILTY-AVR (Frailty in Aortic Valve Replacement) prospective multicenter cohort study was conducted 2012 2017 14 centers 3 countries. Patients ≥70 years of age who underwent transcatheter or surgical AVR were eligible. Mini Nutritional Assessment-Short Form assessed by trained...
Transcatheter aortic valve replacement (TAVR) represents a paradigm shift in the therapeutic options for patients with severe stenosis. However, rapid and exponential growth TAVR demand may overwhelm capacity, translating to inadequate access prolonged wait times. Our objective was evaluate temporal trends times associated clinical consequences.In this population-based study Ontario, Canada, we identified all referrals from April 1, 2010, March 31, 2016. The primary outcome median total time...
Abstract Background and Aims There is significant potential to streamline the clinical pathway for patients undergoing transcatheter aortic valve implantation (TAVI). The purpose of this study was evaluate effect implementing BENCHMARK best practices on efficiency safety TAVI in 28 sites 7 European countries. Methods This a with severe symptomatic stenosis (AS) balloon-expandable valves before after implementation practices. Principal objectives were reduce hospital length stay (LoS)...
Depression is increasingly recognized as a risk factor for adverse outcomes in cardiovascular disease. However, little known about depression older adults undergoing transcatheter (TAVR) or surgical (SAVR) aortic valve replacement.To determine the prevalence of and its association with all-cause mortality TAVR SAVR.This preplanned analysis Frailty Aortic Valve Replacement (FRAILTY-AVR) prospective cohort study included 14 centers 3 countries from November 15, 2011, through April 7, 2016....
Background Women account for a large proportion of patients treated with transcatheter aortic valve replacement, yet there remain conflicting reports about the effect sex on outcomes. Moreover, sex-specific prevalence and prognostic impact frailty has not been systematically studied in context replacement. Methods Results A preplanned analysis FRAILTY-AVR study (Frailty Aortic Valve Replacement) was performed to analyze determinants outcomes older women men undergoing multinational,...
Abstract Background The long‐term clinical performance of transcatheter heart valves (THV) is unknown. Aims This study assessed the outcomes, rate structural valve deterioration (SVD) and bioprosthetic failure in patients after aortic replacement (TAVR) to 10‐year follow‐up. Methods Consecutive undergoing TAVI for native stenosis or failed surgical bioprosthesis, between 2005 2009 at our institution were included. A total 235 consecutive patients. Results At time mean age was 82.4 ± 7.9...