A5022447817- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Cardiac pacing and defibrillation studies
- Cardiovascular Function and Risk Factors
- Cardiac Arrhythmias and Treatments
- Cardiac Structural Anomalies and Repair
- Venous Thromboembolism Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Heart Failure Treatment and Management
- Cardiac Arrest and Resuscitation
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Issues in Pregnancy
- Nutrition and Health in Aging
- Antiplatelet Therapy and Cardiovascular Diseases
- Diabetes Treatment and Management
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Cardiovascular Disease and Adiposity
- Mechanical Circulatory Support Devices
- Acute Ischemic Stroke Management
- Cardiac and Coronary Surgery Techniques
Hadassah Medical Center
2019-2025
Hebrew University of Jerusalem
2019-2025
Manpower Demonstration Research Corporation
2023
Health Sciences Centre
2017-2022
University of Toronto
2017-2022
Sunnybrook Health Science Centre
2017-2022
Poriya Medical Center
2018-2022
Bar-Ilan University
2019-2022
University of East Anglia
2020
Toronto Public Health
2017-2018
We report the maternal and foetal outcomes at birth after 6 months in a cohort of pregnant women with hypertrophic cardiomyopathy (HCM). Although most HCM tolerate pregnancy well, there is an increased risk obstetric cardiovascular complications.All entered into prospective worldwide Registry Pregnancy Cardiac disease (ROPAC) were included this analysis. The primary endpoint was major adverse event (MACE), which death, heart failure (HF), thrombo-embolic event, arrhythmia. Baseline outcome...
Transcatheter aortic valve replacement (TAVR) represents a paradigm shift in the therapeutic options for patients with severe stenosis. However, rapid and exponential growth TAVR demand may overwhelm capacity, translating to inadequate access prolonged wait times. Our objective was evaluate temporal trends times associated clinical consequences.In this population-based study Ontario, Canada, we identified all referrals from April 1, 2010, March 31, 2016. The primary outcome median total time...
Abstract Aims Current guidelines recommend anticoagulation with a vitamin K antagonist to treat left ventricular (LV) thrombus after myocardial infarction (MI). Data on the use of direct oral anticoagulants (DOACs) in this setting are limited. The aim study was assess efficacy apixaban vs. warfarin treating LV MI. Methods and results We conducted prospective, randomized, multicentre open-label clinical trial including patients detected by 2D transthoracic echocardiography 1–14 days acute...
Objective: To assess the initial clinical experience with a novel endograft system (NEXUS Aortic Arch Stent Graft System) designed to treat aortic arch pathologies and address morphology hemodynamic challenges of arch. Summary Background Data: The remains most challenging part aorta for both open endovascular repair. Transcatheter repair has potential significantly reduce surgical risks. Methods: Patients underwent transcatheter single branch, 2 stent graft system, implanted over...
Hemoglobin (Hb) is a standard and widely available clinical parameter that predicts outcomes in heart failure (HF) patients. Red cell distribution width (RDW) also routinely measured predictive of HF. The ratio between Hb RDW has yet to be evaluated HF.We the value Hb/RDW on patients with All diagnosed chronic HF at health maintenance organization were for followed cardiac-related hospitalizations death.The study cohort included 6888 mean was 0.85 ± 0.18; median (interquartile range...
<h3>Importance</h3> The literature is inconsistent regarding the impact of permanent pacemaker implantation after transcatheter aortic valve replacement. <h3>Objective</h3> To evaluate clinical and economic outcomes in patients who required during index hospitalization <h3>Design, Setting, Participants</h3> This retrospective, population-based cohort study using data from a multicenter registry included underwent replacement procedure April 1, 2010, to March 31, 2015, Ontario, Canada, with...
Background Rapid growth in transcatheter aortic valve replacement ( TAVR ) demand has translated to inadequate access, reflected by prolonged wait times. Increasing times are associated with important adverse outcomes while on the wait‐list; however, it is unknown if influence postprocedural outcomes. Our objective was determine association between and Methods Results In this population‐based study Ontario, Canada, we identified all procedures April 1, 2010, March 31, 2016. Wait time defined...
Background Atrial fibrillation (AF) is common and bears a major clinical impact in patients with hypertrophic cardiomyopathy (HCM). We aimed to investigate the use real‐world safety of catheter ablation for AF HCM. Methods Results drew data from US National Inpatient Sample identify cases HCM between 2003 2015. Sociodemographic were collected, incidence complications, mortality, length stay analyzed, including trends early (2003–2008) later (2009–2015) study years. Among weighted total 1563...
Background: Chronic total occlusions (CTO) occur in nearly 20% of coronary angiograms. CTO revascularization, either by percutaneous intervention (PCI) or artery bypass grafting surgery (CABG), is infrequently performed, approximately one-third cases. Long-term outcomes are unknown. The objective the study was to determine whether early revascularization patients, CABG PCI, associated with improved clinical outcomes. Methods: One thousand six hundred twenty-four patients from Canadian...
Based on worldwide registries, approximately 50% of patients who underwent transcatheter aortic valve replacement (TAVR) are female patients. Although TAVR procedures have improved tremendously in recent years, differences outcome including mortality between sexes remain. We aimed to investigate the trends early and new eras utilization assess outcomes vs. male patients.Using 2011-2017 National Inpatient Sample (NIS) database, we identified hospitalizations for with diagnosis stenosis during...
Abstract OBJECTIVES Endovascular aortic arch stent grafting with branched devices has shown initial promising results. The aim of this prospective, multicentre study was to evaluate 3-year outcomes NEXUS® Aortic Arch Stent Graft System (Nexus), a single-branch, bi-modular, off-the-shelf graft system in high-risk patients. METHODS Patients treated Nexus, either under the feasibility clinical or as compassionate use procedures 5 centres, were included study. primary end point overall survival....
Background: Obesity has been associated with increased incidence and severity of various cardiovascular risk factors for stroke. However, the evidence its effect on outcomes in stroke victims have equivocal. We aimed to investigate distribution BMI a nation-wide cohort individuals, admitted stroke, relationship between in-hospital mortality. Methods: Data from U.S. National Inpatient Sample (NIS) was collected, identify hospitalizations October 2015 December 2016. The patients were...
The association between Body Mass Index (BMI) and clinical outcomes following sepsis continues to be debated. We aimed investigate the relationship BMI in-hospital course mortality in patients hospitalized with bacteremic using real-world data. A sampled cohort of October 2015 December 2016 was identified National Inpatient Sample (NIS) database. In-hospital length stay were defined as relevant outcomes. Patients divided into 6 (kg/m2) subgroups; (1) underweight ≤ 19, (2) normal-weight...
Background Routine addition of an atrial lead during implantable cardioverter‐defibrillator (ICD) implantation for primary prevention sudden cardiac death, in patients without pacing indications, was not shown beneficial contemporary studies. We aimed to investigate the use and safety single‐ versus dual‐chamber ICD implantations these patients. Methods Results Using National Inpatient Sample database, we identified with no indications who underwent primary‐prevention United States between...
Based on worldwide registries, approximately 50% of patients who underwent aortic valve replacement (AVR) via surgical are females. Although AVR procedures have improved greatly in recent years, differences outcome including mortality between sexes remain. We aimed to investigate the trends SAVR outcomes females versus males.
Background/Objectives: Atrial fibrillation (AF) and flutter (AFL) are the most common cardiac arrhythmias worldwide. Cardiovascular complications a manifestation of acute post-acute COVID-19 infection. We aimed to analyze nationwide trends in clinical characteristics outcomes patients hospitalized for AF/AFL before during outbreak U.S. Methods: This study is retrospective analysis patients, aged 18 older, between 2016 2020. drew data from National Inpatient Sample (NIS) database. Baseline...
The relationship between body mass index (BMI) and clinical outcomes in patients with cardiovascular disease, including acute heart failure (AHF) myocardial infarction (AMI), remains debated. This study investigates the association BMI within PARADISE-MI cohort, while also evaluating impact of angiotensin receptor-neprilysin inhibitor (ARNI) versus angiotensin-converting enzyme (ACE-I) treatment on this relationship.
Acute coronary syndrome (ACS) at a young age is uncommon. Limited data regarding the long-term follow-up and prognosis in this population are available. Our objectives were to evaluate clinical outcomes of patients presenting with ACS assess factors that predict prognosis.A retrospective analysis consecutive (male below 40 female 50 years old) admitted underwent percutaneous intervention (PCI) between 1997 2009. Demographics, characteristics, including major cardiovascular (CV) events...