Lawrence Rudski

ORCID: 0000-0003-1876-1492
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About
Contact & Profiles
Research Areas
  • Cardiovascular Function and Risk Factors
  • Pulmonary Hypertension Research and Treatments
  • Cardiac Valve Diseases and Treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiac Imaging and Diagnostics
  • Frailty in Older Adults
  • Venous Thromboembolism Diagnosis and Management
  • Infective Endocarditis Diagnosis and Management
  • Congenital Heart Disease Studies
  • Ultrasound in Clinical Applications
  • Hemodynamic Monitoring and Therapy
  • Cardiovascular Effects of Exercise
  • Nutrition and Health in Aging
  • Atrial Fibrillation Management and Outcomes
  • Cardiac Structural Anomalies and Repair
  • Cardiovascular Issues in Pregnancy
  • Cardiovascular and exercise physiology
  • COVID-19 Clinical Research Studies
  • Heart Failure Treatment and Management
  • Hip and Femur Fractures
  • COVID-19 and healthcare impacts
  • Acute Ischemic Stroke Management
  • Antimicrobial Resistance in Staphylococcus
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Pericarditis and Cardiac Tamponade

Jewish General Hospital
2016-2025

McGill University
2016-2025

SickKids Foundation
2024

University of Toronto
2024

Lunenfeld-Tanenbaum Research Institute
2024

University of Ottawa
2024

Queen's University
2024

Ottawa Hospital
2024

Shaheed Rajaei Cardiovascular Medical and Research Center
2022

Association Française pour le Dépistage et la Prévention des Handicaps de l’Enfant
2022

Mechanistic insights from 3D echocardiography (echo) can guide therapy. In particular, ischemic mitral regurgitation (MR) is difficult to repair, often persisting despite annular reduction. We hypothesized that (1) in a chronic infarct model of progressive MR, parallels changes the geometry leaflet attachments, causing increased tethering and restricting closure; therefore, (2) MR be reduced by restoring toward normal, using new ventricular remodeling approach based on echo findings.We...

10.1161/01.cir.101.23.2756 article EN Circulation 2000-06-13

Our study aimed to determine the prevalence of occult left-heart disease in patients with scleroderma and pulmonary hypertension. In hypertension (mean artery pressure PAP) ≥25 mmHg), differentiation between pre- post-capillary has been made according wedge (PAWP) less than or more 15 mmHg, respectively. We performed a retrospective chart review 107 patients. All suspected had routine right left heart catheterisation ventricular end-diastolic (LVEDP) measurement pre-/post-fluid challenge....

10.1183/09031936.00091212 article EN European Respiratory Journal 2012-12-20

Background: Older adults undergoing aortic valve replacement (AVR) are at risk for malnutrition. The association between preprocedural nutritional status and midterm mortality has yet to be determined. Methods: FRAILTY-AVR (Frailty in Aortic Valve Replacement) prospective multicenter cohort study was conducted 2012 2017 14 centers 3 countries. Patients ≥70 years of age who underwent transcatheter or surgical AVR were eligible. Mini Nutritional Assessment-Short Form assessed by trained...

10.1161/circulationaha.118.033887 article EN Circulation 2018-07-05
Luna Gargani Nicola Riccardo Pugliese Nicolò De Biase Matteo Mazzola Gergely Ágoston and 95 more Michele Arcopinto Paola Argiento William F. Armstrong Francesco Bandera Filippo Cademartiri Andreina Carbone Rossana Castaldo Rodolfo Citro Rosangela Cocchia Veronica Codullo Michele D’Alto Antonello D’Andrea Philipp Douschan Iacopo Fabiani Francesco Ferrara Monica Franzese Paolo Frumento Stefano Ghio Ekkehard Grünig Marco Guazzi Jarosław D. Kasprzak Theodore J. Kolias Gábor Kovács André La Gerche Giuseppe Limogelli Alberto M. Marra Marco Matucci‐Cerinic Ciro Mauro Antonella Moreo Lorenza Pratali Brigida Ranieri Salvatore Rega Lawrence Rudski Rajan Saggar Andrea Salzano Walter Serra Anna Agnese Stanziola Mani A. Vannan Damien Voilliot Olga Vriz Karina Wierzbowska‐Drabik Antonio Cittadini Robert Naeije Eduardo Bossone Eduardo Bossone Luna Gargani Robert Naeije Francesco Ferrara William F. Armstrong Theodore J. Kolias Valentina Capone Rosangela Cocchia Ciro Mauro Chiara Sepe Filippo Cademartiri Iacopo Fabiani Francesco Capuano Rodolfo Citro Rossella Maria Benvenga Michele Bellino Giuseppe Iuliano Serena Migliarino Ilaria Radano Antonio Cittadini Michele Arcopinto Alberto M. Marra Giulia Crisci Roberta D’Assante Mariarosaria De Luca Federica Giardino Carmen Rainone Salvatore Rega Valéria Valente Michele D’Alto Paola Argiento Antonello D’Andrea Francesco Ferrara Valentina Russo Luna Gargani Paolo Frumento Matteo Mazzola Santo Dellegrottaglie Giovanni Di Salvo Stefano Ghio Stefania Guida Ekkerard Grunig Christina A. Eichstaedt Marco Guazzi Francesco Bandera Valentina Labate André La Gerch Giuseppe Limongelli Andreina Carbone Giuseppe Pacileo Marina Verrengia

10.1016/j.jacc.2023.09.807 article EN publisher-specific-oa Journal of the American College of Cardiology 2023-11-01

Background Phase angle (PA) is a bioimpedance measurement that determined lean body mass and hydration status. Patients with low PA values are more likely to be frail, sarcopenic, or malnourished. Previous work has shown predicts adverse outcomes after cardiac surgery, but the effect of on survival not previously been assessed in this setting. Methods Results The BICS (Bioimpedance Cardiac Surgery) study recruited 277 patients undergoing major surgery at 2 university-affiliated hospitals...

10.1161/jaha.118.008721 article EN cc-by-nc-nd Journal of the American Heart Association 2018-09-04

Background— Tricuspid regurgitation (TR) is a risk factor for mortality in pulmonary hypertension (PH). TR severity varies among patients with comparable degrees of PH and right ventricular remodeling. The contribution leaflet adaptation to the pathophysiology has yet be examined. We hypothesized that tricuspid area (TLA) increased PH, adequacy this increase relative remodeling determines severity. Methods Results— A prospective cohort 255 from pre postcapillary pathogeneses was assembled 2...

10.1161/circimaging.114.002714 article EN Circulation Cardiovascular Imaging 2015-05-01

The landscape of pulmonary hypertension (PH) has changed significantly since the last Canadian Cardiovascular Society/Canadian Thoracic Society position statement in 2005. Since then, advances our understanding pathophysiology PH and improvements diagnostic therapeutic options have transformed care patients with PH. Globally, an estimated prevalence 1%, increasing to 10% those aged 65 years older, most commonly due left heart or lung disease. Although arterial (PAH) is less common, morbidity...

10.1016/j.cjca.2019.11.041 article EN cc-by-nc Canadian Journal of Cardiology 2020-07-01
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