- Cardiovascular Function and Risk Factors
- Pulmonary Hypertension Research and Treatments
- Cardiac Valve Diseases and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Imaging and Diagnostics
- Frailty in Older Adults
- Venous Thromboembolism Diagnosis and Management
- Infective Endocarditis Diagnosis and Management
- Congenital Heart Disease Studies
- Ultrasound in Clinical Applications
- Hemodynamic Monitoring and Therapy
- Cardiovascular Effects of Exercise
- Nutrition and Health in Aging
- Atrial Fibrillation Management and Outcomes
- Cardiac Structural Anomalies and Repair
- Cardiovascular Issues in Pregnancy
- Cardiovascular and exercise physiology
- COVID-19 Clinical Research Studies
- Heart Failure Treatment and Management
- Hip and Femur Fractures
- COVID-19 and healthcare impacts
- Acute Ischemic Stroke Management
- Antimicrobial Resistance in Staphylococcus
- Chemotherapy-induced cardiotoxicity and mitigation
- Pericarditis and Cardiac Tamponade
Jewish General Hospital
2016-2025
McGill University
2016-2025
SickKids Foundation
2024
University of Toronto
2024
Lunenfeld-Tanenbaum Research Institute
2024
University of Ottawa
2024
Queen's University
2024
Ottawa Hospital
2024
Shaheed Rajaei Cardiovascular Medical and Research Center
2022
Association Française pour le Dépistage et la Prévention des Handicaps de l’Enfant
2022
Pressão do AD B
Mechanistic insights from 3D echocardiography (echo) can guide therapy. In particular, ischemic mitral regurgitation (MR) is difficult to repair, often persisting despite annular reduction. We hypothesized that (1) in a chronic infarct model of progressive MR, parallels changes the geometry leaflet attachments, causing increased tethering and restricting closure; therefore, (2) MR be reduced by restoring toward normal, using new ventricular remodeling approach based on echo findings.We...
Our study aimed to determine the prevalence of occult left-heart disease in patients with scleroderma and pulmonary hypertension. In hypertension (mean artery pressure PAP) ≥25 mmHg), differentiation between pre- post-capillary has been made according wedge (PAWP) less than or more 15 mmHg, respectively. We performed a retrospective chart review 107 patients. All suspected had routine right left heart catheterisation ventricular end-diastolic (LVEDP) measurement pre-/post-fluid challenge....
Background: Older adults undergoing aortic valve replacement (AVR) are at risk for malnutrition. The association between preprocedural nutritional status and midterm mortality has yet to be determined. Methods: FRAILTY-AVR (Frailty in Aortic Valve Replacement) prospective multicenter cohort study was conducted 2012 2017 14 centers 3 countries. Patients ≥70 years of age who underwent transcatheter or surgical AVR were eligible. Mini Nutritional Assessment-Short Form assessed by trained...
Background Phase angle (PA) is a bioimpedance measurement that determined lean body mass and hydration status. Patients with low PA values are more likely to be frail, sarcopenic, or malnourished. Previous work has shown predicts adverse outcomes after cardiac surgery, but the effect of on survival not previously been assessed in this setting. Methods Results The BICS (Bioimpedance Cardiac Surgery) study recruited 277 patients undergoing major surgery at 2 university-affiliated hospitals...
Background— Tricuspid regurgitation (TR) is a risk factor for mortality in pulmonary hypertension (PH). TR severity varies among patients with comparable degrees of PH and right ventricular remodeling. The contribution leaflet adaptation to the pathophysiology has yet be examined. We hypothesized that tricuspid area (TLA) increased PH, adequacy this increase relative remodeling determines severity. Methods Results— A prospective cohort 255 from pre postcapillary pathogeneses was assembled 2...
The landscape of pulmonary hypertension (PH) has changed significantly since the last Canadian Cardiovascular Society/Canadian Thoracic Society position statement in 2005. Since then, advances our understanding pathophysiology PH and improvements diagnostic therapeutic options have transformed care patients with PH. Globally, an estimated prevalence 1%, increasing to 10% those aged 65 years older, most commonly due left heart or lung disease. Although arterial (PAH) is less common, morbidity...