Denisa Muraru

ORCID: 0000-0003-2514-3668
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About
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Research Areas
  • Cardiovascular Function and Risk Factors
  • Cardiac Valve Diseases and Treatments
  • Cardiac Imaging and Diagnostics
  • Pulmonary Hypertension Research and Treatments
  • Infective Endocarditis Diagnosis and Management
  • Congenital Heart Disease Studies
  • Atrial Fibrillation Management and Outcomes
  • Cardiac Arrhythmias and Treatments
  • Cardiac Structural Anomalies and Repair
  • Cardiovascular Effects of Exercise
  • Cardiac pacing and defibrillation studies
  • Aortic Disease and Treatment Approaches
  • Advanced MRI Techniques and Applications
  • Cardiomyopathy and Myosin Studies
  • Cardiovascular Disease and Adiposity
  • Ultrasound in Clinical Applications
  • Hemodynamic Monitoring and Therapy
  • Cardiac tumors and thrombi
  • Advanced X-ray and CT Imaging
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiovascular Issues in Pregnancy
  • Systemic Sclerosis and Related Diseases
  • Pericarditis and Cardiac Tamponade
  • Cardiovascular Health and Disease Prevention
  • Cardiac electrophysiology and arrhythmias

IRCCS Istituto Auxologico Italiano
2019-2025

Istituti di Ricovero e Cura a Carattere Scientifico
2019-2025

University of Milano-Bicocca
2019-2025

Semmelweis University
2024

Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2022

Hopital Universitaire Hedi Chaker
2022

Maria Cecilia Hospital
2022

University of Padua
2012-2021

Umeå University
2020

European Society of Cardiology
2015-2019

Approximately 4% of subjects aged 75 years or more have clinically relevant tricuspid regurgitation (TR). Primary TR results from anatomical abnormality the valve apparatus and is observed in only 8-10% patients with disease. Secondary common arises as a result annular dilation caused by right ventricular enlargement dysfunction consequence pulmonary hypertension, often left-sided heart disease atrial fibrillation. Irrespective its aetiology, leads to volume overload increased wall stress,...

10.4244/eij-d-21-00695 article EN EuroIntervention 2021-11-01

Right ventricular (RV) volumes and ejection fraction (EF) vary significantly with demographic anthropometric factors are associated poor prognosis in several cardiovascular diseases. This multicenter study was designed to (1) establish the reference values for RV EF using transthoracic three-dimensional (3D) echocardiography; (2) investigate influence of age, sex, body size on anatomy; (3) develop normative equations.RV (end-diastolic volume end-systolic volume), stroke volume, were measured...

10.1161/circimaging.113.000706 article EN Circulation Cardiovascular Imaging 2013-06-29

Aims(i) To validate a new software for right ventricular (RV) analysis by 3D echocardiography (3DE) against cardiac magnetic resonance (CMR); (ii) to assess the accuracy of different measurement approaches; and (iii) explore any benefits vs. previous software.

10.1093/ehjci/jev309 article EN European Heart Journal - Cardiovascular Imaging 2015-12-08

Background— Despite the fact that assessment of right ventricular longitudinal strain (RVLS) carries important implications for patient diagnosis, prognosis, and treatment, its implementation in clinical settings has been hampered by limited reference values lack uniformity software, method, definition used measuring RVLS. Accordingly, this study was designed to establish (1) RVLS 2-dimensional speckle-tracking echocardiography; (2) their relationship with demographic, hemodynamic, cardiac...

10.1161/circimaging.115.003866 article EN Circulation Cardiovascular Imaging 2016-02-01
Julien Dreyfus Xavier Galloo Maurizio Taramasso Gregor Heitzinger Giovanni Benfari and 95 more Karl-Patrick Kresoja Fernando M. Juarez-Casso Hazem Omran Yohann Bohbot Christos Iliadis Giulio Russo Yan Topilsky Marcel Weber Luis Nombela‐Franco Alessandra Sala Andrea Eixerés‐Esteve Bernard Iung Jean‐François Obadia Rodrigo Estévez‐Loureiro Elisabeth Riant Erwan Donal Jörg Hausleiter Luigi P. Badano Thierry Le Tourneau Augustin Coisne Thomas Modine Azeem Latib Fabien Praz Stephan Windecker José Luis Zamorano Ralph Stephan von Bardeleben Gilbert H.L. Tang Rebecca T. Hahn John G. Webb Denisa Muraru Mohammed Nejjari Vincent Chan Michele De Bonis Manuel Carnero Georg Nickenig Roman Pfister Christophe Tribouilloy Volker Rudolph Juan A. Crestanello Philipp Lurz Philipp E. Bartko Francesco Maisano Jeroen J. Bax Maurice Enriquez‐Sarano David Messika‐Zeitoun Julien Dreyfus Xavier Galloo Maurizio Taramasso Gregor Heitzinger Giovanni Benfari Karl-Patrick Kresoja Fernando M. Juarez-Casso Hazem Omran Yohan Bohbot Christos Iliadis Giulio Russo Yan Topilsky Marcel Weber Luis Nombela‐Franco Alessandra Sala Andrea Eixerés‐Esteve Bernard Iung Jean‐François Obadia Rodrigo Estévez‐Loureiro Elisabeth Riant Pascal Lim Baptiste Bazire Erwan Donal Jörg Hausleiter Luigi P. Badano Thierry Le Tourneau Augustin Coisne Thomas Modine Yoan Lavie‐Badie Fabien Doguet Gilbert Habib Christine Selton‐Suty N Ajmone-Marsan Azeem Latib Lukas Stolz Fabien Praz Stephan Windecker José Luís Zamorano Ralph Stephan von Bardeleben T. Ruf Gilbert H.L. Tang Rebecca T. Hahn Edith Lubos John A. Webb Joachim Schöfer Neil Fam Alexander Lauten Giovanni Pedrazzini Josep Rodés‐Cabau Denisa Muraru

Abstract Background and aims Benefit of tricuspid regurgitation (TR) correction timing intervention are unclear. This study aimed to compare survival rates after surgical or transcatheter conservative management according a TR clinical stage as assessed using the TRI-SCORE. Methods A total 2,413 patients with severe isolated functional were enrolled in TRIGISTRY (1217 conservatively managed, 551 valve surgery, 645 repair). The primary endpoint was at 2 years. Results TRI-SCORE low (≤3) 32%,...

10.1093/eurheartj/ehad585 article EN European Heart Journal 2023-08-25

Abstract Atrial secondary tricuspid regurgitation (A-STR) is a distinct phenotype of with predominant dilation the right atrium and normal left ventricular function. occurs most commonly in elderly women atrial fibrillation heart failure preserved ejection fraction sinus rhythm. In A-STR, main mechanism leaflet malcoaptation related to presence significant annulus enlargement. addition, there an insufficient adaptive growth valve leaflets that become unable cover enlarged annular area. As...

10.1093/eurheartj/ehae088 article EN cc-by-nc European Heart Journal 2024-03-05
Julien Dreyfus Maurizio Taramasso Karl‐Patrik Kresoja Hazem Omran Christos Iliadis and 95 more Giulio Russo Marcel Weber Luis Nombela‐Franco Rodrigo Estévez‐Loureiro Jörg Hausleiter Azeem Latib Lukas Stolz Fabien Praz Stephan Windecker José Luís Zamorano Ralph Stephan von Bardeleben Gilbert H.L. Tang Rebecca T. Hahn Edith Lubos John A. Webb Joachim Schöfer Neil Fam Alexander Lauten Giovanni Pedrazzini Josep Rodés‐Cabau Mohammed Nejjari Luigi P. Badano Hannes Alessandrini Dominique Himbert Horst Sievert Kerstin Piayda Erwan Donal Thomas Modine Georg Nickenig Roman Pfister Volker Rudolph Jordan Bernick George A. Wells Jeroen J. Bax Philipp Lurz Maurice Enriquez‐Sarano Francesco Maisano David Messika‐Zeitoun N Ajmone-Marsan Hannes Alessandrini Luigi P. Badano Philipp E. Bartko Jeroen J. Bax Baptiste Bazire Giovanni Benfari Jordan Bernick Yohan Bohbot Manuel Carnero Vincent Chan Augustin Coisne Juan A. Crestanello Michele De Bonis Fabien Doguet Erwan Donal Julien Dreyfus Florian Eggenspieler Maurice Enriquez‐Sarano Andrea Eixerés‐Esteve Rodrigo Estévez‐Loureiro Damien Eyharts Neil Fam Michele Flagiello Xavier Galloo Mara Gavazzoni Gilbert Habib Rebecca T. Hahn Jörg Hausleiter Gregor Heitzinger Dominique Himbert Christos Iliadis Bernard Iung Fernando M. Juarez-Casso Karl-Patrick Kresoja Azeem Latib Alexander Lauten Yoan Lavie‐Badie Thierry Le Tourneau Pascal Lim Edith Lubos Philipp Lurz Francesco Maisano Yannick Mbaki Héctor I. Michelena Thomas Modine David Messika‐Zeitoun Denisa Muraru Mohammed Nejjari Georg Nickenig Martin Nicol Luis Nombela‐Franco Jean‐François Obadia Hazem Omran Giovanni Pedrazzini Roman Pfister Kerstin Piayda

10.1016/j.jcin.2024.04.023 article EN КАРДИОЛОГИЯ УЗБЕКИСТАНА 2024-05-16

Right atrial (RA) size predicts the outcome in some pathological conditions but reference values for RA volumes and myocardial function remain to be defined. Thus, we used two-dimensional speckle-tracking echocardiography (2D-STE) three-dimensional (3DE) define normative of function. Two hundreds healthy volunteers (43 ± 15 years, range 18–75; 44% men) underwent (2DE) obtain longitudinal strain (LS) wall using 2D-STE, 3DE measure maximal (Vmax), minimal, preA calculate total, passive, active...

10.1093/ehjci/jet024 article EN European Heart Journal - Cardiovascular Imaging 2013-02-19

Our study sought to (1) identify reference values for left atrial (LA) volumes and phasic function indices by 3-dimensional echocardiography (3DE) compare them with those measured 2-dimensional (2DE) (2) analyze their relationship age, sex, body size, ventricular function. Accuracy reproducibility of 3DE 2DE have been also tested evaluate the robustness our data.We obtained maximal, minimal, preA LA in 276 healthy volunteers (18-79 years; 57% women). Limits normality total emptying fraction...

10.1161/circimaging.115.004229 article EN Circulation Cardiovascular Imaging 2016-07-01
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