A5066334106- Blood Pressure and Hypertension Studies
- Healthcare Systems and Practices
- Health, Medicine and Society
- Cardiovascular Health and Disease Prevention
- Nutritional Studies and Diet
- Heart Failure Treatment and Management
- Antibiotic Use and Resistance
- Cardiovascular Syncope and Autonomic Disorders
- Heart Rate Variability and Autonomic Control
- Patient Satisfaction in Healthcare
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Pharmacology and Obesity Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Clinical practice guidelines implementation
- Cardiovascular Disease and Adiposity
- Cardiac and Coronary Surgery Techniques
- Obesity, Physical Activity, Diet
- Atrial Fibrillation Management and Outcomes
- Vaccine Coverage and Hesitancy
- Sodium Intake and Health
- Obstructive Sleep Apnea Research
- Venous Thromboembolism Diagnosis and Management
- Nutrition and Health in Aging
- Pregnancy and preeclampsia studies
French Clinical Research Infrastructure Network
2016-2025
Université de Lorraine
2016-2025
Inserm
2015-2025
European School of Haematology
2025
Centre d'Investigation Clinique Pierre Drouin
2014-2024
Défaillance Cardiovasculaire Aiguë et Chronique
2013-2024
Centre Hospitalier Régional et Universitaire de Nancy
1995-2024
Générale de Santé
2016-2018
Centre d’Investigation Clinique Innovation Technologique de Nancy
1999-2018
Centre de Médecine Préventive
2014-2017
Arterial stiffening and thickening endothelial dysfunction may be associated with cognitive decline or white matter hyperintensities (WMH) independently of blood pressure level. We aimed to investigate, using an integrative approach, the relative contributions structural functional vascular factors degree impairment (primary outcome) severity WMH (secondary in elderly hypertensive patients subjective memory complaints, a group prone dementia.A prospective, dedicated, cross-sectional...
This study sought to identify homogenous echocardiographic phenotypes in community-based cohorts and assess their association with outcomes.Asymptomatic cardiac dysfunction leads a high risk of long-term cardiovascular morbidity mortality; however, better classification asymptomatic individuals remains challenge.Echocardiographic were identified using K-means clustering the first generation STANISLAS (Yearly non-invasive follow-up Health status Lorraine insured inhabitants) cohort (N = 827;...
Background Carotid intima–media thickness ( cIMT ) is a noninvasive marker of cardiovascular risk. The may be increased in patients with harmonisation, but little known regarding the functional form association between blood pressure BP and hypertensive nonhypertensive persons. We aimed to define shape . Methods Results studied ambulatory monitoring data from single‐center, cross‐sectional, population‐based study involving 696 adult participants STANISLAS cohort, familial longitudinal cohort...
High blood pressure in pregnancy remains, by its complications, the leading cause of morbidity as well maternal and fetal mortality. The frequency (5-10% pregnancies) potential severity this disease, for both mother child, encourage to standardize optimize our medical practices. If short-term complications child are known, long-term ones beginning be better identified. onset hypertension during disrupts classic organization health care requires intervention general practitioner and/or an...
Long-chain polyunsaturated fatty acids (PUFAs) generate diverse bioactive lipid mediators, which tightly regulate vascular inflammation. The effects of omega-3 PUFA supplementation in cardiovascular prevention however remain controversial. In addition to direct dietary intake, acid desaturases (FADS) determine levels. Increased arterial stiffness represents an independent predictor mortality and events. aim the present study was association FADS1 genotype, FADS expression with stiffness. A...
Purpose The implementation of hypertension guidelines into the everyday practice general practitioners (GPs) have an outmost importance to provide optimal care for patients. aim our study was, on one hand gain insight about relationship between societies and GP societies, other hand, get feedback use single pill combinations (SPC) in each country, as indicator guideline implementation.
Previous studies investigating autonomic cardiovascular control in elderly persons usually included analysis of R-R interval but not blood pressure variability. "Physiological" rise during the aging process was accounted for as a possible confounding factor. This study designed to characterize relationship between age and short-term heart rate (HR) (BP) variability, independently "physiological" BP associated aging. The carried out 65 "normotensive" (BP ≤ 140/80 mm Hg) healthy subjects,...
Objectives To assess the implementation of home blood pressure measurement (HBPM) by French general practitioners (GPs) in current practice 2009 and to evolution practices between 2004 2009; perceived benefits limitations method; adherence methodological European [European Society Hypertension (ESH) 2007] or [La Haute Autorité de Santé (HAS) 2005] recommendations. Method Two phone surveys on a representative random sample GPs then 2009. Results Five hundred forty 801 were contacted 2009,...
Introduction : La télémédecine constitue une nouvelle forme de pratique médicale dont le développement est aujourd’hui en pleine expansion. Elle trouve un écho particulier dans certains territoires lorrains où déficit médecins généralistes et spécialistes nécessite nouvelles formes pratiques. L’objectif cette étude était d’explorer les représentations la télémédecine, téléconsultation particulier, des exerçant zones déficitaires offre soins Lorraine d’identifier avantages désavantages perçus...
Background PCSK9 (Proprotein convertase subtilisin/kexin type 9) binds low-density lipoprotein receptor, preventing its recycling. is a risk predictor and biotarget in atherosclerosis. The PCSK9-rs562556 variant has been reported as gain-of-function mutation. aim of this study was to determine whether the PCSK9-low-density receptor-rs562556 axis associated with carotid artery plaques between 2 visits separated by almost 20 years longitudinal population cohort. Methods Results STANISLAS...
Abstract Aims Several dimensions of eating behaviour (EB), such as restrained (RE), appear to be cross-sectionally associated with certain cardiovascular (CV) diseases and metabolic risk factors although little is known regarding longitudinal associations. This study aimed assess the associations between EB CV damage or syndrome after 13 years, in initially healthy individuals. Methods results included 1109 participants from familial STANISLAS (Suivi Temporaire Annuel Non-Invasif de la Santé...
Abstract BACKGROUND Recent studies have shown that hyperuricemia may be associated with incident hypertension (HTN). We examined whether serum uric acid (SUA) is a predictor of HTN and target organ damage (TOD) 20 years later in initially healthy middle-aged individuals. METHODS Participants from the Suivi Temporaire Annuel Non-Invasif de la Santé des Lorrains Assurés Sociaux (STANISLAS) single-center familial longitudinal cohort study (961 adults 570 children) underwent clinical laboratory...
Background Potassium disturbances are associated with adverse prognosis in patients chronic conditions. Its prognostic implications stable attending the emergency department (ED) is poorly described. Aims This study aimed to assess prevalence of dyskalemia, describe its predisposing factors and associations a population presenting ED without unstable medical illness. Methods Post-hoc analysis prospective, cross-sectional, multicenter 11 French academic hospitals over period 8 weeks. All...