A5042670390- Liver Disease Diagnosis and Treatment
- Bariatric Surgery and Outcomes
- Thyroid Disorders and Treatments
- Diabetes Treatment and Management
- Diet and metabolism studies
- Diet, Metabolism, and Disease
- Gastric Cancer Management and Outcomes
- Cardiovascular Function and Risk Factors
- Neuroendocrine Tumor Research Advances
- Ion channel regulation and function
- Diabetes Management and Research
- Growth Hormone and Insulin-like Growth Factors
- Cardiovascular Disease and Adiposity
- Heart Failure Treatment and Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Metabolism, Diabetes, and Cancer
- Thyroid Cancer Diagnosis and Treatment
- Parathyroid Disorders and Treatments
- Gut microbiota and health
- Pharmacology and Obesity Treatment
- Pituitary Gland Disorders and Treatments
- Adrenal Hormones and Disorders
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal Tumor Research and Treatment
- Diabetic Foot Ulcer Assessment and Management
Hospital de São João
2019-2024
Universidade do Porto
2015-2024
Secretaria Municipal de Saúde
2024
Czech Academy of Sciences, Institute of Physiology
2023
Diabetes Australia
2023
Faculdade de Medicina do ABC
2022-2023
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
2022
Centro Hospitalar do Porto
2019
Hospital de Santa Maria
2011
To perform a post hoc analysis of the FIGHT trial, evaluating effect liraglutide (vs. placebo) on totality events in patients with heart failure reduced ejection fraction (HFrEF).FIGHT was double-blind randomized controlled trial (RCT) that studied versus placebo 300 recently hospitalized HFrEF followed for 180 days. The main outcome present total hospitalizations (HF) or all-cause death. Secondary outcomes included arrhythmic and prespecified interest (arrhythmias, sudden cardiac death,...
Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic disease. NAFLD often occurs associated with endocrinopathies. Evidence suggests that endocrine dysfunction may play an important role in development, progression, and severity. Our work aimed to explore summarize crosstalk between different organs, their hormones, dysfunctions. For instance, our results show hyperprolactinemia, hypercortisolemia, polycystic ovary syndrome seem worsen NAFLD’s pathway. Hypothyroidism low...
Aim The prevalence of thyroid nodules and the risk cancer in patients with Graves’ disease is uncertain. We aimed to evaluate disease. Methods Retrospective observational study adult subjects Graves' (positive autoantibodies thyrotropin receptor antibodies (TRAbs)) between 2017 2021 at our center was done. evaluated this population characterized predictive factors for malignancy using linear logistic regression models. Results a total 539 during median follow-up 3.3 years (25th–75th...
Bariatric surgery leads to weight loss and cardiometabolic risk improvement. Although prediabetes remission after bariatric is biologically plausible, data on this topic scarce. We aimed assess rate clinical predictors of in a 4 year follow up period.
Background Thyroid hormones are important modulators of cardiovascular function. Both hypothyroidism and hyperthyroidism known to contribute an increased risk. It remains uncertain whether thyroid level within the euthyroid range associated with cardiometabolic We aimed evaluate association between function levels risk in a population-based cohort. Methods Eight hundred thirty-five subjects aged ≥45 years from EPIPorto cohort were included. excluded participants TSH, free T4 (FT4), or T3...
Background PCSK9 (Proprotein convertase subtilisin/kexin type 9) binds low-density lipoprotein receptor, preventing its recycling. is a risk predictor and biotarget in atherosclerosis. The PCSK9-rs562556 variant has been reported as gain-of-function mutation. aim of this study was to determine whether the PCSK9-low-density receptor-rs562556 axis associated with carotid artery plaques between 2 visits separated by almost 20 years longitudinal population cohort. Methods Results STANISLAS...
Background: An association between hypothyroidism and the risk of Non-alcoholic Fatty Liver Disease (NAFLD) has been suggested. This remains to be elucidated in patients with morbid obesity. Aim: To evaluate thyroid function parameters liver hepatic scores Methods: Patients obesity followed our centre January 2010 July 2018 were included. The ones without evaluation functions excluded. Index (FLI) BARD used as predictors steatosis fibrosis, respectively. Results: We observed a positive TSH...
We aimed to evaluate the association between vitamin D status and hepatic function parameters scores: Fatty Liver Index (FLI, predictor of steatosis) BARD (BMI, AST/ALT ratio DM, fibrosis) in patients with morbid obesity.Cross-sectional study including obesity followed our centre January 2010 July 2018. Patients missing levels or profile were excluded. divided population according two cut-offs (12ng/mL 20ng/mL).The included (n=1124) had an average age 43.3±10.7 years 84.3% female....
Non-alcoholic fatty liver disease (NAFLD) is associated with several other metabolic disorders, which are typically pro-inflammatory states. Body fat content an important marker of health and abdominal harmful cardiometabolic outcomes. We aimed to evaluate the association between risk NAFLD (through Fatty Liver Index (FLI), BMI, AST/ALT ratio, presence diabetes (BARD)), anthropometric parameters, predictors status, in patients morbid obesity, FLI BARD scores markers. have retrospectively...
Hypothyroidism and hyperthyroidism are associated with marked changes in cardiac structure function. However, the association of thyroid function within normal range general population remains uncertain.Eight hundred thirty-five subjects aged ≥45 years from EPIPorto cohort (evaluation between 2006 2008) were cross-sectionally analyzed. We excluded participants TSH, free T4 (FT4), or T3 (FT3) outside reference self-reported cardiovascular disease. Cardiac evaluated by echocardiography. used...