A5009596234- Thyroid Disorders and Treatments
- Liver Disease Diagnosis and Treatment
- Cardiovascular Function and Risk Factors
- Diet, Metabolism, and Disease
- Ion channel regulation and function
- Cardiac Imaging and Diagnostics
- Heart Failure Treatment and Management
- Growth Hormone and Insulin-like Growth Factors
- Adipose Tissue and Metabolism
- Diet and metabolism studies
- Medical Imaging Techniques and Applications
- Diabetes Treatment and Management
- Cleft Lip and Palate Research
- Hormonal Regulation and Hypertension
- Alcohol Consumption and Health Effects
- Streptococcal Infections and Treatments
- Body Contouring and Surgery
- Esophageal Cancer Research and Treatment
- Pancreatitis Pathology and Treatment
- Cardiac tumors and thrombi
- Prenatal Screening and Diagnostics
- Craniofacial Disorders and Treatments
- Liver Disease and Transplantation
- Actinomycetales infections and treatment
- Neonatal Respiratory Health Research
Universidade do Porto
2018-2025
Administração Regional de Saúde de Lisboa e Vale do Tejo
2025
Hospital de São João
2022-2024
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
2024
Czech Academy of Sciences, Institute of Physiology
2023
Diabetes Australia
2023
Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic disease. NAFLD often occurs associated with endocrinopathies. Evidence suggests that endocrine dysfunction may play an important role in development, progression, and severity. Our work aimed to explore summarize crosstalk between different organs, their hormones, dysfunctions. For instance, our results show hyperprolactinemia, hypercortisolemia, polycystic ovary syndrome seem worsen NAFLD’s pathway. Hypothyroidism low...
Abstract Introduction It is estimated that most people undergoing bariatric surgery are women of reproductive age; nonetheless, its effects on pregnancy outcomes not yet fully understood. Methods Retrospective observational study, conducted in a tertiary center Portugal, included participants two groups: (1) pregnant with history ( n = 89) and (2) BMI ≥ 35 kg/m2, without previous 176). Data was collected from the medical files. Multivariate analysis to adjust for confounders. Results...
We present a compelling case of female infant with axillary intertrigo, presumptively caused by streptococcal infection, successfully treated topical antibiotics. This highlights distinctive clinical features that aid in differentiating intertrigo from other skin fold infections, emphasising its diagnostic and therapeutic implications. Of particular importance, this report underscores the potential for negative smear cultures despite an underlying aetiology, advocating critical role...
Background Thyroid hormones are important modulators of cardiovascular function. Both hypothyroidism and hyperthyroidism known to contribute an increased risk. It remains uncertain whether thyroid level within the euthyroid range associated with cardiometabolic We aimed evaluate association between function levels risk in a population-based cohort. Methods Eight hundred thirty-five subjects aged ≥45 years from EPIPorto cohort were included. excluded participants TSH, free T4 (FT4), or T3...
Background: An association between hypothyroidism and the risk of Non-alcoholic Fatty Liver Disease (NAFLD) has been suggested. This remains to be elucidated in patients with morbid obesity. Aim: To evaluate thyroid function parameters liver hepatic scores Methods: Patients obesity followed our centre January 2010 July 2018 were included. The ones without evaluation functions excluded. Index (FLI) BARD used as predictors steatosis fibrosis, respectively. Results: We observed a positive TSH...
We aimed to evaluate the association between vitamin D status and hepatic function parameters scores: Fatty Liver Index (FLI, predictor of steatosis) BARD (BMI, AST/ALT ratio DM, fibrosis) in patients with morbid obesity.Cross-sectional study including obesity followed our centre January 2010 July 2018. Patients missing levels or profile were excluded. divided population according two cut-offs (12ng/mL 20ng/mL).The included (n=1124) had an average age 43.3±10.7 years 84.3% female....
Thyroid dysfunction is common in patients with heart failure (HF). Impaired conversion of free T4 (FT4) into T3 (FT3) thought to occur these patients, decreasing the availability FT3 and contributing HF progression. In preserved ejection fraction (HFpEF), it not known whether changes thyroid hormones (THs) are associated clinical status outcomes.The objective this study was evaluate association FT3/FT4 ratio TH clinical, analytical, echocardiographic parameters, as well their prognostic...
Abstract Prenatal diagnosis of orofacial clefts allows adequate counseling and planning for prenatal care delivery. In 2001, two‐dimensional ultrasound screening became universally used in Portugal by government guidelines, after 2007 more advanced available. This study aimed to describe the prevalence family history patients with analyze born before between 2001 2007. Retrospective analysis a cohort followed trans‐disciplinary team tertiary hospital. A total 672 OFCs were identified: 40.9%...
Acquired cold-induced urticaria is a rare form of physical urticaria, especially in children. The variety clinical presentations and the low estimated prevalence contribute to its underdiagnosis. Given associated risk anaphylaxis, it crucial alert clinicians different forms presentation, diagnosis, treatment. Starting with case report acquired previously healthy nine-year-old boy, authors then review literature about discuss diagnostic exams disease management.
Caregivers of children with complex chronic diseases (CCD) or life-limiting conditions (LLC) experience heightened strain. Understanding their concerns is essential for effective support, particularly in pediatric palliative care (PPC) where compassionate support crucial. Amid substantial growth PPC services Portugal, assessing the effectiveness addressing these and adapting to evolving needs parents imperative. The aim this study was perceive impact from caregivers' perspective.
Background: Low levels of triiodothyronine (T3) are common in patients with heart failure (HF). Our aim was to evaluate the effects supplementation low and replacement doses T3 an animal model HF preserved ejection fraction (HFpEF). Methods: We evaluated four groups: ZSF1 Lean (n = 8, Lean-Ctrl), Obese (rat metabolic-induced HFpEF, n 13, HFpEF), treated a dose HFpEF-T3high), low-dose HFpEF-T3low). administered drinking water from weeks 13 24. The animals underwent anthropometric metabolic...
Thyroid hormones (TH) are crucial for cardiovascular homeostasis. Recent evidence suggests that acute conditions, particularly heart failure (AHF), significantly impair the thyroid axis. Our aim was to evaluate association of function with parameters and short- long-term clinical outcomes in AHF patients. We performed a single-centre retrospective cohort study including patients hospitalized between January 2012 December 2017. used linear, logistic, Cox proportional hazard regression models...
As hormonas tiroideias encontram-se intrinsecamente relacionadas com o sistema cardiovascular, pelo que é expectável as disfunções da função tiroideia, incluindo subclínicas tiroide,
Introduction: Data regarding the referral of patients with metabolic syndrome (MetS) to hepatologists is scarce.Most authors agree that at-risk (including ones diabetes or MetS) should be screened for non-alcoholic fatty liver disease (NAFLD) and referred when needed.Existing data highlights NAFLD specialists remain low among endocrinologists.Our aim was evaluate a Portuguese cohort MetS followed in Endocrinology outpatient setting their need hepatologists.Methods: Secondary analysis...