Diana Bordalo
- Asthma and respiratory diseases
- Mobile Health and mHealth Applications
- Urticaria and Related Conditions
- Medication Adherence and Compliance
- Mitochondrial Function and Pathology
- Digital Mental Health Interventions
- Allergic Rhinitis and Sensitization
- Metabolism and Genetic Disorders
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- ATP Synthase and ATPases Research
- Inhalation and Respiratory Drug Delivery
- Autoimmune Bullous Skin Diseases
- Respiratory and Cough-Related Research
- Cystic Fibrosis Research Advances
- Pediatric health and respiratory diseases
- Health Literacy and Information Accessibility
- Genetic Syndromes and Imprinting
- Social Media in Health Education
- Trauma and Emergency Care Studies
- Renin-Angiotensin System Studies
- Venous Thromboembolism Diagnosis and Management
- Occupational Health and Burnout
- Breastfeeding Practices and Influences
- Air Quality Monitoring and Forecasting
- Medical Malpractice and Liability Issues
Universidade do Porto
2019-2025
Hospital de São João
2022-2024
Centre for Health Technology and Services Research
2019-2021
Pediatrics and Genetics
2021
Centro Hospitalar do Porto
2016-2020
University Hospital Heidelberg
2018
Heidelberg University
2018
A 13-year-old female presented to the Emergency Department with sudden-onset swelling of left hand. She reported a similar episode 2 weeks before involving ankle spontaneous resolution and monthly abdominal pain fainting over past 4 months. Due severe dysmenorrhoea, she had been prescribed combined oral contraceptive pill by her general practitioner 5 months prior. Her previous history included hospitalisation at age for knee unknown aetiology. denied taking other drugs, insect bites,...
Poor medication adherence is a major challenge in asthma, and objective assessment of inhaler needed. The InspirerMundi app aims to monitor while providing positive experience through gamification social support.
Objectives Anxiety and depression are relevant comorbidities in asthma, but, Portugal Spain, data on this topic scarce. We assessed, patients with the frequency of anxiety using Hospital Depression Scale (HADS) European Quality Life Five Dimension Questionnaire (EQ-5D); level agreement between these questionnaires, factors associated symptoms. Methods This is a secondary analysis INSPIRERS studies. A total 614 adolescents adults persistent asthma (32.6±16.9 years, 64.7% female) were...
We aimed to compare patient's and physician's ratings of inhaled medication adherence identify predictors patient-physician discordance. Baseline data from two prospective multicentre observational studies. 29 allergy, pulmonology paediatric secondary care outpatient clinics in Portugal. 395 patients (≥13 years old) with persistent asthma. Data on demographics, relationship, upper airway control, asthma treatment, forced expiratory volume one second (FEV1) healthcare use were collected....
Background Health and fitness apps have potential benefits to improve self-management disease control among patients with asthma. However, inconsistent use rates been reported across studies, regions, health systems. A better understanding of the characteristics users nonusers is critical design solutions that are effectively integrated in patients’ daily lives, ensure these equitably reach out different groups patients, thus improving rather than entrenching inequities. Objective This study...
Supplementary Figure 3. Bland-Altman plots of Control Allergic Rhinitis and Asthma Test (CARAT) sub scores (upper airways CARAT-UA lower CARAT-LA) obtained through paper (pCARAT), app (mCARAT) telephone (tCARAT) *The dashed lines represent the bias dot-dashed 95% limits agreement
We aimed to identify persistent asthma phenotypes among adolescents and evaluate longitudinally asthma-related outcomes across phenotypes. Adolescents (13-17 years) from the prospective, observational, multicenter INSPIRERS studies, conducted in Portugal Spain, were included (n = 162). Latent class analysis was applied demographic, environmental, clinical variables, collected at a baseline medical visit. Longitudinal differences variables assessed 4-month follow-up telephone contact 128)....
Background: Poor medication adherence is a major challenge in asthma and objective assessment of inhaler needed. InspirerMundi app aims to monitor while turning it into positive experience through gamification social support. Objective: We assessed the medium-term feasibility real-world patients with persistent (treated daily inhaled medication). In addition, we attempted identify characteristics related higher use. Methods: Two multicenter observational studies, one initial face-to-face...
Acquired cold-induced urticaria is a rare form of physical urticaria, especially in children. The variety clinical presentations and the low estimated prevalence contribute to its underdiagnosis. Given associated risk anaphylaxis, it crucial alert clinicians different forms presentation, diagnosis, treatment. Starting with case report acquired previously healthy nine-year-old boy, authors then review literature about discuss diagnostic exams disease management.
InspirerMundi app aims to transform adherence into a positive experience through gamification and social support, while allowing objective monitoring of inhaler adherence. We explored patients' engagement with this app. Adolescents adults persistent asthma, followed in 24 Portuguese hospital outpatient clinics, were invited by their physicians use the daily for 4 months register medication symptoms. To stimulate engagement, includes component (point badge system storyline warrior evolving an...
Aims: To identify distinct asthma control clusters based on Control of Allergic Rhinitis and Asthma Test (CARAT) to compare patients’ characteristics among these clusters. Methods: Adults adolescents (≥13 years) with persistent were recruited at 29 Portuguese hospital outpatient clinics, in the context two observational studies INSPIRERS project. Demographic clinical characteristics, adherence inhaled medication, beliefs about anxiety depression, quality life, (CARAT, >24 good control)...
Background Urticaria typically involves the skin and mucosa is characterized by development of wheals, angioedema, or both. According to temporal evolution lesions, urticaria classified as acute (AU) chronic (CU), depending on whether episodes last for fewer more than six weeks, respectively. This study aimed characterize a group children adolescents with describe its subtypes, associated comorbidities, treatment, evolution. Methodology retrospective, observational included patients aged <18...
We aimed to identify persistent asthma phenotypes among adolescents and evaluate, longitudinally, their asthma-related outcomes. A secondary analysis was performed on the prospective, observational multicenter INSPIRERS studies, 162 (13–17 years; 51% male) were analysed. Latent class applied 10 variables easily collected in baseline medical visits, both at primary care, comprehending demographic, environmental, clinical domains. Longitudinal changes assessed a 4-month telephone visit...
the third series of experiments, mice were randomly divided into two groups: 1.Control group: (sham operated) and 2. isc/rep group (30' isc 8 min rep).Myocardial mitochondria isolated, treated with MLS2776 MLS2778 (from 10μm to 0.01μm) Calcium Retention Capacity (CRC) was estimated.GSK3β localization in cytosolic mitochondrial fractions confirmed by Western Blot.Results: Both reduced IS (14.72±1.36%and 15.36±1.88%vs 45.12±2.15% Control group).Furthermore, GSK3β phosphorylation at Ser9 found...
BACKGROUNDAsthma is the most frequent chronic disease in pediatrics with a rising incidence and prevalence last 30 years [1][2][3] Physical activity (PA) highly recommended asthmatic patients whom obesity sedentary behaviour may contribute to worse control [4][5][6][7] PA reduce asthma symptoms by: -increasing exercise tolerance capacity -inducing anti-inflammatory effects 8 AIMS METHODSTo describe predictors of severity children adolescents -Cross-sectional study -3 months -Asthma +...