Michael Doumas

ORCID: 0000-0002-7269-8044
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About
Contact & Profiles
Research Areas
  • Blood Pressure and Hypertension Studies
  • Diabetes Treatment and Management
  • Heart Rate Variability and Autonomic Control
  • Hormonal Regulation and Hypertension
  • Lipoproteins and Cardiovascular Health
  • Cardiovascular Health and Disease Prevention
  • Sexual function and dysfunction studies
  • Cardiovascular and exercise physiology
  • Hormonal and reproductive studies
  • Cardiovascular Function and Risk Factors
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Diabetes Management and Research
  • Pharmacology and Obesity Treatment
  • Metabolism, Diabetes, and Cancer
  • Liver Disease Diagnosis and Treatment
  • Potassium and Related Disorders
  • Heart Failure Treatment and Management
  • COVID-19 Clinical Research Studies
  • Cardiovascular Disease and Adiposity
  • Sodium Intake and Health
  • Cancer, Lipids, and Metabolism
  • Cerebrovascular and Carotid Artery Diseases
  • Chronic Kidney Disease and Diabetes
  • Menopause: Health Impacts and Treatments
  • Adrenal and Paraganglionic Tumors

Aristotle University of Thessaloniki
2016-2025

George Washington University
2015-2024

Washington University Medical Center
2015-2024

Veterans Health Administration
2009-2024

Georgetown University
2011-2024

Washington DC VA Medical Center
2014-2024

Ippokrateio General Hospital of Thessaloniki
1996-2024

401 General Military Hospital of Athens
2024

Gdańsk Medical University
2024

University of South Carolina
2023

Document Reviewers: Luis Alcocer (Mexico), Christina Antza (Greece), Mustafa Arici (Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luís Bronze (Portugal), John Chalmers (Australia), Tine De Backer (Belgium), Alejandro de la Sierra (Spain), Kyriakos Dimitriadis Dorota Drozdz (Poland), Béatrice Duly-Bouhanick (France), Brent M. Egan (USA), Serap Erdine Claudio Ferri (Italy), Slavomira Filipova (Slovak Republic), Anthony Heagerty (UK), Michael Hecht Olsen (Denmark), Dagmara Hering...

10.1097/hjh.0000000000003480 article EN Journal of Hypertension 2023-06-24

Abstract Neutrophils and complement are key sentinels of innate immunity mediators acute inflammation. Recent studies have suggested that inflammatory processes modulate thrombogenic pathways. To date, the potential cross-talk between thrombosis precise molecular pathway by which neutrophils trigger coagulation process remained elusive. In this study, we demonstrate antiphospholipid Ab-induced activation downstream signaling via C5a receptors in leads to induction tissue factor (TF), a...

10.4049/jimmunol.177.7.4794 article EN The Journal of Immunology 2006-10-01

Abstract Early increase of soluble urokinase plasminogen activator receptor (suPAR) serum levels is indicative increased risk progression coronavirus disease 2019 (COVID-19) to respiratory failure. The SAVE-MORE double-blind, randomized controlled trial evaluated the efficacy and safety anakinra, an IL-1α/β inhibitor, in 594 patients with COVID-19 at progressing failure as identified by plasma suPAR ≥6 ng ml −1 , 85.9% ( n = 510) whom were receiving dexamethasone. At day 28, adjusted...

10.1038/s41591-021-01499-z article EN cc-by Nature Medicine 2021-09-03

Epidemiological findings, based largely on middle-aged populations, support an inverse and independent association between exercise capacity mortality risk. The information available in older individuals is limited.Between 1986 2008, we assessed the all-cause 5314 male veterans aged 65 to 92 years (mean+/-SD, 71.4+/-5.0 years) who completed test at Veterans Affairs Medical Centers Washington, DC, Palo Alto, Calif. We established fitness categories peak metabolic equivalents (METs) achieved....

10.1161/circulationaha.110.938852 article EN Circulation 2010-08-10

Prehypertension is likely to progress hypertension. The rate of progression determined mostly by age and resting blood pressure but may also be attenuated increased fitness. A graded exercise test was performed in 2303 men with prehypertension at the Veterans Affairs Medical Centers Washington, DC. Four fitness categories were defined, based on peak metabolic equivalents (METs) achieved. We assessed association between capacity hypertension (HTN). median follow-up period 7.8 years (mean (±...

10.1161/hypertensionaha.112.196493 article EN Hypertension 2012-07-03

Unilateral primary aldosteronism is the most common surgically correctable form of endocrine hypertension and usually differentiated from bilateral forms by adrenal venous sampling (AVS) or computed tomography (CT). Our objective was to compare clinical biochemical postsurgical outcomes patients with unilateral diagnosed CT AVS identify predictors surgical outcomes. Patient data were obtained 18 internationally distributed centers retrospectively analyzed for adrenalectomy management based...

10.1161/hypertensionaha.118.11382 article EN Hypertension 2018-07-09

: Primary aldosteronism is a frequent cause of secondary hypertension requiring specific pharmacological treatment with mineralocorticoid receptor antagonist or unilateral adrenalectomy. These treatments have shown to reduce the excess cardiovascular risk characteristically associated this disease. In part I consensus, we discussed procedures for diagnosis primary aldosteronism. present II, address strategies differential subtypes and therapy. We also discuss evaluation outcomes provide...

10.1097/hjh.0000000000002520 article EN Journal of Hypertension 2020-06-26

Objectives Female sexual dysfunction (FSD) is increasingly attracting more scientific and public interest, represents a poorly investigated issue in patients with essential hypertension. We evaluated the prevalence of hypertensive women compared normotensive according to age, hypertension severity, duration, antihypertensive treatment. Methods The study population consisted consecutive, sexually active attending an outpatient clinic. Sexual Function Index (FSFI questionnaire) was used...

10.1097/01.hjh.0000251898.40002.5b article EN Journal of Hypertension 2006-11-02

Arterial hypertension is considered a risk factor for erectile dysfunction. The aim of the study was to evaluate prevalence dysfunction in hypertensive compared with normotensive individuals similar demographic characteristics Greece. Furthermore, effect age, severity, duration, and antihypertension medication on function these subjects investigated. population consisted 634 consecutive young middle-aged men (31-65 years) that visited our outpatient clinic. From them, 358 patients had...

10.2164/jandrol.04191 article EN Andrology 2006-04-19
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