A5107441436- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Health and Disease Prevention
- Stroke Rehabilitation and Recovery
- Blood Pressure and Hypertension Studies
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Health and Risk Factors
- Cardiovascular Function and Risk Factors
- Venous Thromboembolism Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Cardiovascular Disease and Adiposity
- Antiplatelet Therapy and Cardiovascular Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurological Disorders and Treatments
- Intracranial Aneurysms: Treatment and Complications
- Cardiovascular and Diving-Related Complications
- Dementia and Cognitive Impairment Research
- Nutritional Studies and Diet
- Neurological Disease Mechanisms and Treatments
- Genetic Associations and Epidemiology
- Lipoproteins and Cardiovascular Health
- Cerebral Venous Sinus Thrombosis
- Aortic Thrombus and Embolism
- Cardiac Arrhythmias and Treatments
University of Miami
2016-2025
Dr. John T. Macdonald Foundation
2012-2025
Hudson Institute
2024
John Wiley & Sons (United States)
2024
American Heart Association
2006-2023
Jackson Memorial Hospital
2011-2023
Luigi Sacco Hospital
2012-2023
University of South Florida
2016-2023
Florida International University
2012-2023
Baptist Health South Florida
2023
Despite the global impact and advances in understanding pathophysiology of cerebrovascular diseases, term "stroke" is not consistently defined clinical practice, research, or assessments public health. The classic definition mainly does account for science technology. Stroke Council American Heart Association/American Association convened a writing group to develop an expert consensus document updated stroke 21st century. Central nervous system infarction as brain, spinal cord, retinal cell...
The aim of this new statement is to provide comprehensive and timely evidence-based recommendations on the prevention ischemic stroke among survivors or transient attack. Evidence-based are included for control risk factors, interventional approaches atherosclerotic disease, antithrombotic treatments cardioembolism, use antiplatelet agents noncardioembolic stroke. Further provided recurrent in a variety other specific circumstances, including arterial dissections; patent foramen ovale;...
The American Heart Association makes every effort to avoid any actual or potential conflicts of interest that may arise as a result an outside relationship
Stroke remains the second-leading cause of death and third-leading disability combined (as expressed by disability-adjusted life-years lost - DALYs) in world. The estimated global cost stroke is over US$721 billion (0.66% GDP). From 1990 to 2019, burden (in terms absolute number cases) increased substantially (70.0% increase incident strokes, 43.0% deaths from stroke, 102.0% prevalent 143.0% DALYs), with bulk (86.0% 89.0% residing lower-income lower-middle-income countries (LMIC). This World...
The aim of this updated statement is to provide comprehensive and timely evidence-based recommendations on the prevention ischemic stroke among survivors or transient attack. Evidence-based are included for control risk factors, interventional approaches atherosclerotic disease, antithrombotic treatments cardioembolism, use antiplatelet agents noncardioembolic stroke. Further provided recurrent in a variety other specific circumstances, including arterial dissections; patent foramen ovale;...
This guideline provides an overview of the evidence on various established and potential stroke risk factors recommendations for reduction risk.Writing group members were nominated by committee chair basis each writer's previous work in relevant topic areas approved American Heart Association Stroke Council's Scientific Statement Oversight Committee. The writers used systematic literature reviews (covering time period since last review published 2001 up to January 2005), reference previously...
Despite the use of antiplatelet agents, usually aspirin, in patients who have had an ischemic stroke, there is still a substantial rate recurrence. Therefore, we investigated whether warfarin, which effective and superior to aspirin prevention cardiogenic embolism, would also prove recurrent stroke with prior noncardioembolic stroke.
Background and Purpose The aim of this investigation was to determine the importance race as a determinant intracranial atherosclerotic stroke in community-based sample. Methods Residents from northern Manhattan over age 39 years hospitalized for acute ischemic (n=438, black 35%, Hispanic 46%, white 19%) were prospectively evaluated. Index strokes classified (17%), lacunar (30%), cardioembolic (21%), cryptogenic (31%), other (1%). Atherosclerotic infarcts subdivided into extracranial (9%)...
Background — Patent foramen ovale (PFO) is associated with stroke, but there are no randomized studies to evaluate the efficacy of antithrombotic therapies. Methods and Results The PFO in Cryptogenic Stroke Study was a 42-center study that evaluated transesophageal echocardiographic findings patients randomly assigned warfarin or aspirin Warfarin-Aspirin Recurrent Study. In this study, 630 stroke were enrolled, whom 312 (49.5%) 318 (50.5%) aspirin. Of these, 265 experienced cryptogenic 365...
Recurrent stroke is a frequent, disabling event after ischemic stroke. This study compared the efficacy and safety of two antiplatelet regimens--aspirin plus extended-release dipyridamole (ASA-ERDP) versus clopidogrel.In this double-blind, 2-by-2 factorial trial, we randomly assigned patients to receive 25 mg aspirin 200 twice daily or 75 clopidogrel daily. The primary outcome was first recurrence secondary composite stroke, myocardial infarction, death from vascular causes. Sequential...
Abstract In a prospective study of 1,805 hospitalized patients in the Stroke Data Bank National Institute Neurological and Communicative Disorders Stroke, 1,273 with infarction were classified into diagnostic subtypes. Diagnosis was based on clinical history, examination, laboratory tests including computed tomography, noninvasive vascular imaging, where safe relevant, angiography. Five hundred eight cases (fully 40%) labeled as infarcts undetermined cause (IUC), which 138 (27%) evaluated...
Stroke is a leading cause of disability, cognitive impairment, and death in the United States accounts for 1.7% national health expenditures. Because population aging risk stroke more than doubles each successive decade after age 55 years, these costs are anticipated to rise dramatically. The objective this report was project future annual care from 2012 2030 discuss potential cost reduction strategies.The American Heart Association/American Association developed methodology stroke-related...
Prolonged lowering of blood pressure after a stroke reduces the risk recurrent stroke. In addition, inhibition renin-angiotensin system in high-risk patients rate subsequent cardiovascular events, including However, effect with inhibitor soon has not been clearly established. We evaluated effects therapy an angiotensin-receptor blocker, telmisartan, initiated early stroke.In multicenter trial involving 20,332 who recently had ischemic stroke, we randomly assigned 10,146 to receive...
Cryptogenic strokes constitute 20 to 30% of ischemic strokes, and most cryptogenic are considered be embolic undetermined source. An earlier randomized trial showed that rivaroxaban is no more effective than aspirin in preventing recurrent stroke after a presumed from an Whether dabigatran would this type was unclear.
We conducted a retrospective, multicenter study to compare the efficacy of warfarin with aspirin for prevention major vascular events (ischemic stroke, myocardial infarction, or sudden death) in patients symptomatic stenosis intracranial artery.Patients 50 99% an artery (carotid; anterior, middle, posterior cerebral; vertebral; basilar) were identified by reviewing results consecutive angiograms performed at participating centers between 1985 and 1991. Only TIA stroke territory stenotic...
To determine and compare the prevalence of patent foramen ovale in patients with stroke undetermined origin (cryptogenic) determined to assess possible role as a risk factor for cryptogenic stroke.Cross-sectional study nested case-control analysis.A total 146 (73 men, 73 women) acute ischemic referred echocardiography laboratory evaluation.Neurovascular Unit Echocardiography Laboratory, Columbia-Presbyterian Medical Center, New York, York.Patients were considered have strokes or according...