A5044376308- Acute Myocardial Infarction Research
- Cardiac Arrest and Resuscitation
- Heart Failure Treatment and Management
- Cardiac Health and Mental Health
- Cardiac Imaging and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Lipoproteins and Cardiovascular Health
- Mechanical Circulatory Support Devices
- Health Systems, Economic Evaluations, Quality of Life
- Emergency and Acute Care Studies
- Trauma and Emergency Care Studies
- Chronic Disease Management Strategies
- Cardiac, Anesthesia and Surgical Outcomes
- Stroke Rehabilitation and Recovery
- Sepsis Diagnosis and Treatment
- Cardiac electrophysiology and arrhythmias
- Cardiovascular and exercise physiology
- Medication Adherence and Compliance
- Telemedicine and Telehealth Implementation
- Coronary Interventions and Diagnostics
- Pharmaceutical Economics and Policy
- Cardiovascular Effects of Exercise
- Disaster Response and Management
- Takotsubo Cardiomyopathy and Associated Phenomena
- Diabetes Treatment and Management
University of Gothenburg
2017-2025
Sahlgrenska University Hospital
2016-2025
Region Västra Götaland
2019
Stockholm South General Hospital
2017
University of Borås
2017
Linköping University
2017
Karlstad Central Hospital
2017
Lund University
2017
Karolinska University Hospital
2017
Karolinska Institutet
2017
Impact of changes treatments on outcomes in ST-elevation myocardial infarction (STEMI) patients real-life health care has not been documented. All STEMI cases (n = 105.674) registered the nation-wide SWEDEHEART registry between 1995 and 2014 were included followed for fatal non-fatal up to 20 years. Most treatment occurred from 1994 2008. Evidence-based increased: reperfusion 66.2 81.7%; primary percutaneous coronary intervention: 4.5 78.0%; dual antiplatelet therapy 0 89.6%; statin: 14.1...
The clinical effect of routine oxygen therapy in patients with suspected acute myocardial infarction who do not have hypoxemia at baseline is uncertain.In this registry-based randomized trial, we used nationwide Swedish registries for patient enrollment and data collection. Patients an saturation 90% or higher were randomly assigned to receive either supplemental (6 liters per minute 6 12 hours, delivered through open face mask) ambient air.A total 6629 enrolled. median duration was 11.6 the...
Most trials that have shown a benefit of beta-blocker treatment after myocardial infarction included patients with large infarctions and were conducted in an era before modern biomarker-based diagnosis percutaneous coronary intervention, antithrombotic agents, high-intensity statins, renin-angiotensin-aldosterone system antagonists.
Abstract Aims Trends in characteristics, management, and survival out-of-hospital cardiac arrest (OHCA) in-hospital (IHCA) were studied the Swedish Cardiopulmonary Resuscitation Registry (SCRR). Methods results The SCRR was used to study 106 296 cases of OHCA (1990–2020) 30 032 IHCA (2004–20) whom resuscitation attempted. In OHCA, increased from 5.7% 1990 10.1% 2011 remained unchanged thereafter. Odds ratios [ORs, 95% confidence interval (CI)] for 2017–20 vs. 1990–93 2.17 (1.93–2.43)...
We assessed the changes in short- and long-term outcomes their relation to implementation of new evidence-based treatments all patients with non-ST-elevation myocardial infarction (NSTEMI) Sweden over 20 years. Cases NSTEMI (n = 205 693) between 1995 2014 were included from nationwide Swedish Web-System for Enhancement Development Evidence-Based Care Heart Disease Evaluated According Recommended Therapies (SWEDEHEART) registry. During years in-hospital invasive procedures increased 1.9%...
There have been few studies of the outcome in elderly patients who suffered in-hospital cardiac arrest (IHCA) and association between characteristics survival.The aim this large observational study was to investigate survival neurological after IHCA, identify which factors were associated with survival.We investigated IHCA (≥70years age) registered Swedish Cardiopulmonary Resuscitation Registry 2007-2015. For descriptive purposes, grouped according age (70-79, 80-89, ≥90years). Predictors...
Background: The comparative efficacy and safety of ticagrelor versus clopidogrel in older patients with myocardial infarction (MI) has received limited study. Methods: We performed an observational analysis all ≥80 years (n=14 005) who were discharged alive aspirin combined either (60.2%) or (39.8%) after a MI between 2010 2017 registered the national registry SWEDEHEART (Swedish Web-System for Enhancement Development Evidence-Based Care Heart Disease Evaluated According to Recommended...
Abstract Introduction Chest pain is one of the most common reasons for contacting emergency medical services (EMS). It difficult EMS personnel to distinguish between patients suffering from a high-risk condition in need prompt hospital care and suitable non-conveyance. A vast majority with chest are therefore transported department (ED) further investigation even if not necessary. Improved prehospital assessment risk stratification, thus accurately safely identifying non-conveyance, could...
Abstract Introduction Studies examining the factors linked to survival after out of hospital cardiac arrest (OHCA) have either aimed describe characteristics and outcomes OHCA in different parts world, or focused on certain whether they were associated with survival. Unfortunately, this approach does not measure how strong each factor is predicting OHCA. Aim To investigate relative importance 16 well-recognized at time point ambulance arrival, before any interventions medications given, by...
To describe the time trends of in-hospital and out-of-hospital bleeding parallel to development new treatments ischaemic outcomes over last 20 years in a nationwide myocardial infarction (MI) population.Patients with acute MI (n = 371 431) enrolled SWEDEHEART registry from 1995 until May 2018 were selected evaluated for events at 1 year. In-hospital increased 0.5% peak 2% 2005/2006 thereafter slightly decreased plateau around 1.3% by end study period. Out-of-hospital stepwise fashion 2.5%...
Objective To assess the contemporary prevalence of, and factors associated with angina pectoris symptoms, to examine relationship coronary atherosclerosis in a middle-aged, general population. Methods Data were based on Swedish CArdioPulmonary bioImage Study (SCAPIS), which 30 154 individuals randomly recruited from population between 2013 2018. Participants that completed Rose Angina Questionnaire included categorised as or no angina. Subjects valid CT angiography (CCTA) by degree of...
Despite abundant knowledge about the relationship between inflammation and coronary atherosclerosis, it is still unknown whether systemic measured as high-sensitivity C-reactive protein (hsCRP) associated with atherosclerosis in a general population. This study aimed to examine association hsCRP computed tomography angiography (CCTA)-detected population-based cohort. Out of 30,154 randomly invited men women aged 50 64 years Swedish Cardiopulmonary Bioimage Study (SCAPIS), 25,408 had...
Abstract Aims In the Randomized Evaluation of Decreased Usage Beta-Blockers after Acute Myocardial Infarction (REDUCE-AMI) study, long-term beta-blocker use in patients acute myocardial infarction (AMI) with preserved left ventricular ejection fraction demonstrated no effect on death or cardiovascular outcomes. The aim this prespecified substudy was to investigate effects beta-blockers self-reported quality life and well-being. Methods results From parallel-group, open-label, registry-based...
Data on the prognostic value of frailty to guide clinical decision-making for patients with myocardial infarction (MI) are scarce. To analyse association between classification, treatment patterns, in-hospital outcomes, and 6-month mortality in a large population MI.An observational, multicentre study retrospective analysis prospectively collected data using SWEDEHEART registry. In total, 3381 MI level assessed Clinical Frailty Scale (CFS-9) were included. Of these patients, 2509 (74.2%)...
Abstract Aims Most trials showing benefit of beta-blocker treatment after myocardial infarction (MI) included patients with large MIs and are from an era before modern biomarker-based MI diagnosis reperfusion treatment. The aim the randomized evaluation decreased usage beta-blockers acute (REDUCE-AMI) trial is to determine whether long-term oral beta-blockade in preserved left ventricular ejection fraction (EF) reduces composite endpoint death any cause or recurrent MI. Methods results It a...
ABSTRACT Aims To investigate adherence and non‐adherence to treatment regimens among heart failure patients explore relationships with symptom burden hospitalisation frequency. Design The research employed a cross‐sectional survey study design. Methods online “Living failure”, was conducted attending the Cardiac outpatient clinic at Swedish University Hospital over course of calendar year. Data analysis descriptive statistics using statistical processing program SPSS. Results made accessible...
Abstract Background Cardiac telerehabilitation addresses common barriers for attendance at exercise-based cardiac rehabilitation (EBCR). Pragmatic real-world studies are however lacking, limiting generalisability of available evidence. We aimed to evaluate feasibility, safety, and patient perceptions remotely delivered EBCR in a multicentre clinical practice setting after myocardial infarction (MI). Methods This study included 232 post-MI patients (63.7 years, 77.5% men) from 23 centres...
<b><i>Background:</i></b> Exercise is often recommended in migraine treatment, but strenuous physical activity also reported as a trigger. The main aim of this study was to evaluate whether can be triggered by maximal exercise test, using prospective test-retest method. A secondary compare the participants who responded test with attack those did not suffer after test. <b><i>Methods:</i></b> total 19 patients reporting potential trigger for...
In the DETO2X-AMI trial (Determination of Role Oxygen in Suspected Acute Myocardial Infarction), we compared supplemental oxygen with ambient air normoxemic patients presenting suspected myocardial infarction and found no significant survival benefit at 1 year. However, important secondary end points were not yet available. We now report prespecified cardiovascular death composite all-cause hospitalization for heart failure.In this pragmatic, registry-based randomized clinical trial, used a...