A5027907899- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Mechanical Circulatory Support Devices
- Advanced MRI Techniques and Applications
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrest and Resuscitation
- Acute Myocardial Infarction Research
- Poisoning and overdose treatments
- Plant-based Medicinal Research
- Psychedelics and Drug Studies
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Cardiac, Anesthesia and Surgical Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
Karolinska Institutet
2014-2024
Stockholm South General Hospital
1999-2024
Routine intracoronary thrombus aspiration before primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) has not been proved to reduce short-term mortality. We evaluated clinical outcomes at 1 year after aspiration.We randomly assigned 7244 STEMI undergo manual followed by PCI or alone, a registry-based, randomized trial. The end point of all-cause mortality 30 days reported previously. Death from any cause was prespecified...
Background Morphine administration is a strong predictor of delayed onset action orally administered ticagrelor in patients with ST-segment-elevation myocardial infarction, likely because impaired gastrointestinal motility. The aim this study was to evaluate whether the peripheral opioid antagonist methylnaltrexone could improve pharmacodynamics and pharmacokinetics infarction receiving morphine. Methods Results MOVEMENT (Methylnaltrexone Improve Platelet Inhibition Ticagrelor...
The index of microcirculatory resistance is an invasive measure coronary microvascular function that has to be calculated during maximal hyperemia, classically achieved with intravenous adenosine (IV). aim this study was evaluate the use intracoronary (IC) for calculation IMR.31 patients stable artery disease were included in study. Coronary pressure and thermodilution measurements obtained at rest hyperemia using a pressure-temperature sensor-tipped guidewire. Duplicate performed first IC...