- Cardiac Arrest and Resuscitation
- Trauma and Emergency Care Studies
- Emergency and Acute Care Studies
- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Healthcare Technology and Patient Monitoring
- Disaster Response and Management
- Thermal Regulation in Medicine
- Family and Patient Care in Intensive Care Units
- Mechanical Circulatory Support Devices
- Urological Disorders and Treatments
- Prostate Cancer Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Urinary Bladder and Prostate Research
- Cardiovascular Effects of Exercise
- Air Quality and Health Impacts
- Cardiac pacing and defibrillation studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Sepsis Diagnosis and Treatment
- Heart Rate Variability and Autonomic Control
- Climate Change and Health Impacts
- Cardiac electrophysiology and arrhythmias
- Social and Educational Sciences
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury Research
Karolinska Institutet
2016-2025
Stockholm South General Hospital
2014-2025
Region Västra Götaland
2024
University of North Carolina at Chapel Hill
2007-2023
Resuscitation Council
2015
Karolinska University Hospital
2007-2013
University of Michigan–Dearborn
1988
Three million people in Sweden are trained cardiopulmonary resuscitation (CPR). Whether this training increases the frequency of bystander CPR or survival rate among persons who have out-of-hospital cardiac arrests has been questioned.We analyzed a total 30,381 witnessed from January 1, 1990, through December 31, 2011, to determine whether was performed before arrival emergency medical services (EMS) and early correlated with survival.CPR EMS 15,512 cases (51.1%) not 14,869 (48.9%). The...
Cardiopulmonary resuscitation (CPR) performed by bystanders is associated with increased survival rates among persons out-of-hospital cardiac arrest. We investigated whether of bystander-initiated CPR could be the use a mobile-phone positioning system that instantly locate users and dispatch lay volunteers who were trained in to patient nearby
Although sudden cardiac death (SCD) is recognized as a high-priority public health topic, reliable estimates of the incidence SCD or, more broadly, out-of-hospital arrest (OHCA), in population are scarce, especially European Union.The study objective was to determine and OHCA examined 4 large (ie, >2 million inhabitants) population-based prospective registries collecting emergency medical services (EMS)-attended with attempted resuscitation) (OHCA without obvious extracardiac causes) for >5...
<h3>Importance</h3> Therapeutic hypothermia may increase survival with good neurologic outcome after cardiac arrest. Trans-nasal evaporative cooling is a method used to induce cooling, primarily of the brain, during cardiopulmonary resuscitation (ie, intra-arrest). <h3>Objective</h3> To determine whether prehospital trans-nasal intra-arrest improves compared initiated hospital arrival. <h3>Design, Setting, and Participants</h3> The PRINCESS trial was an investigator-initiated, randomized,...
Background: In out-of-hospital cardiac arrest, chest compression–only cardiopulmonary resuscitation (CO-CPR) has emerged as an alternative to standard CPR (S-CPR), using both compressions and rescue breaths. Since 2010, guidelines recommend CO-CPR for untrained bystanders trained unwilling perform The aim of this study was describe changes in the rate type performed before arrival emergency medical services (EMS) during 3 consecutive guideline periods correlation 30-day survival. Methods:...
Patients suffering out-of-hospital cardiac arrest (OHCA) have a poor prognosis but survival among subgroups differs greatly. Previous studies shown conflicting results on whether patient comorbidity affects outcome. The aim of this national study was to investigate the effect outcome after OHCA in Sweden.We included all patients with bystander-witnessed from 2011 2015 Swedish Registry Cardiopulmonary Resuscitation. In order assess comorbidity, database merged comprehensive National Patient...
BackgroundA novel approach to improve bystander defibrillation for out-of-hospital cardiac arrests is dispatch and deliver an automated external defibrillator (AED) directly the suspected arrest location by drone. The aim of this study was investigate how often a drone could AED before ambulance arrival measure median time benefit achieved deliveries.MethodsIn prospective observational study, five AED-equipped drones were placed within two separate controlled airspaces in Sweden, covering...
Although ozone (O3) and other pollutants have been associated with cardiovascular morbidity mortality, the effects of O3 on out-of-hospital cardiac arrest (OHCA) rarely addressed existing studies presented inconsistent findings. The objective this study was to determine short-term exposure air pollution including occurrence OHCA, assess effect modification by season, age, gender. A total 5973 Emergency Medical Service-assessed OHCA cases in Stockholm County 2000–10 were obtained from Swedish...
To evaluate the effect of learning curve on operative, postoperative, and pathological outcomes first 67 totally intracorporeal robot-assisted radical cystectomies (RARCs) with neobladders performed by two lead surgeons at Karolinska University Hospital.Between December 2003 October 2012, patients (61 men six women) underwent RARC orthotopic urinary diversion main surgeons. Data were collected prospectively patient demographics, peri- postoperative including operation times, conversion...
Abstract Background In Europe, survival rates after out-of-hospital cardiac arrest (OHCA) vary widely. Presence/absence and differences in implementation of systems dispatching First Responders (FR) order to arrive before Emergency Medical Services (EMS) may contribute this variation. A comprehensive overview the different types FR-systems used across Europe is lacking. Methods mixed-method survey information retrieved from national resuscitation councils EMS services were as a basis for an...
AimFast recognition of out-of-hospital cardiac arrest (OHCA) by dispatchers might increase survival. The aim this observational study emergency calls was to (1) examine whether a machine learning framework (ML) can the proportion recognizing OHCA within first minute compared with dispatchers, (2) present performance ML different false positive rate (FPR) settings, (3) call characteristics influencing recognition.MethodsML be configured FPR i.e., more or less inclined suspect an depending on...
Smartphone dispatch of volunteer responders to nearby out-of-hospital cardiac arrests (OHCAs) has emerged in several emergency medical services, but no randomized clinical trials have evaluated the effect on bystander use automated external defibrillators (AEDs).To evaluate if AED could be increased by smartphone-aided lay with instructions collect AEDs compared go directly patients OHCAs start cardiopulmonary resuscitation (CPR).This trial assessed a system for smartphone individuals...
Abstract Aims Previous studies have indicated a poorer survival among women following out-of-hospital cardiac arrest (OHCA), but the mechanisms explaining this difference remain largely uncertain. This study aimed to assess after OHCA and men explore role of potential mediators, such as resuscitation characteristics, prior comorbidity, socioeconomic factors. Methods results was population-based cohort including emergency medical service-treated reported Swedish Registry for Cardiopulmonary...
Abstract Aims In the Randomized Evaluation of Decreased Usage Beta-Blockers after Acute Myocardial Infarction (REDUCE-AMI) study, long-term beta-blocker use in patients acute myocardial infarction (AMI) with preserved left ventricular ejection fraction demonstrated no effect on death or cardiovascular outcomes. The aim this prespecified substudy was to investigate effects beta-blockers self-reported quality life and well-being. Methods results From parallel-group, open-label, registry-based...
<b>Objective:</b> To describe the implementation and evaluation of a web-based medication error reporting system. <b>Design:</b> Evaluation study. <b>Setting:</b> Long-term care. <b>Participants:</b> 25 nursing homes in US state North Carolina. <b>Intervention:</b> Detailed information about all errors occurring facility during 1 year period was entered into An survey conducted to assess usability potential for system prevent errors. <b>Main outcome measures:</b> Number specific...
Objective To evaluate the role of positive surgical margin (PSM) size/focality and location in relation to risk biochemical recurrence (BCR) after robot-assisted radical prostatectomy (RARP). Patients Methods Clinicopathological data were collected from 904 patients who underwent RARP at a single European institution 2002 2006. PSM status was defined as cancer cells inked margin, stratified by location. The outcome variable BCR, postoperative PSA level ≥0.2 ng/mL. We modelled...