A5067479574- Cardiac Arrest and Resuscitation
- Trauma and Emergency Care Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Emergency and Acute Care Studies
- Thermal Regulation in Medicine
- Poisoning and overdose treatments
- Disaster Response and Management
- Family and Patient Care in Intensive Care Units
- Mechanical Circulatory Support Devices
- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Traumatic Brain Injury Research
- Palliative Care and End-of-Life Issues
- Healthcare Technology and Patient Monitoring
- Healthcare Decision-Making and Restraints
- Injury Epidemiology and Prevention
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Anesthesia and Pain Management
- Nausea and vomiting management
- Traffic and Road Safety
- Obstructive Sleep Apnea Research
- Autopsy Techniques and Outcomes
- Neuroscience of respiration and sleep
- Heart Rate Variability and Autonomic Control
- Sepsis Diagnosis and Treatment
Södertälje Sjukhus
2016-2024
Stockholm South General Hospital
2014-2024
Karolinska Institutet
2015-2024
Karolinska University Hospital
2009-2021
Swedish Species Information Centre
2016-2018
<h3>Importance</h3> Therapeutic hypothermia may increase survival with good neurologic outcome after cardiac arrest. Trans-nasal evaporative cooling is a method used to induce cooling, primarily of the brain, during cardiopulmonary resuscitation (ie, intra-arrest). <h3>Objective</h3> To determine whether prehospital trans-nasal intra-arrest improves compared initiated hospital arrival. <h3>Design, Setting, and Participants</h3> The PRINCESS trial was an investigator-initiated, randomized,...
Background: In out-of-hospital cardiac arrest, chest compression–only cardiopulmonary resuscitation (CO-CPR) has emerged as an alternative to standard CPR (S-CPR), using both compressions and rescue breaths. Since 2010, guidelines recommend CO-CPR for untrained bystanders trained unwilling perform The aim of this study was describe changes in the rate type performed before arrival emergency medical services (EMS) during 3 consecutive guideline periods correlation 30-day survival. Methods:...
Out-of-hospital cardiac arrest (OHCA) affects some 275,000 individuals in Europe each year. Time from collapse to defibrillation is essential for survival. As emergency medical services (EMS) response times Sweden have increased, novel methods are needed facilitate early treatment. Unmanned aerial vehicles (i.e. drones) potential deliver automated external defibrillators (AED). The aim of this simulation study was explore bystanders’ experience a simulated OHCA-situation where drone delivers...
Abstract Aims Early defibrillation is critical for the chance of survival in out-of-hospital cardiac arrest (OHCA). Drones, used to deliver automated external defibrillators (AEDs), may shorten time defibrillation, but this has never been evaluated real-life emergencies. The aim study was investigate feasibility AED delivery by drones cases OHCA. Methods and results In prospective clinical trial, three AED-equipped were placed within controlled airspace Sweden, covering approximately 80 000...
BackgroundA novel approach to improve bystander defibrillation for out-of-hospital cardiac arrests is dispatch and deliver an automated external defibrillator (AED) directly the suspected arrest location by drone. The aim of this study was investigate how often a drone could AED before ambulance arrival measure median time benefit achieved deliveries.MethodsIn prospective observational study, five AED-equipped drones were placed within two separate controlled airspaces in Sweden, covering...
AimFast recognition of out-of-hospital cardiac arrest (OHCA) by dispatchers might increase survival. The aim this observational study emergency calls was to (1) examine whether a machine learning framework (ML) can the proportion recognizing OHCA within first minute compared with dispatchers, (2) present performance ML different false positive rate (FPR) settings, (3) call characteristics influencing recognition.MethodsML be configured FPR i.e., more or less inclined suspect an depending on...
Smartphone dispatch of volunteer responders to nearby out-of-hospital cardiac arrests (OHCAs) has emerged in several emergency medical services, but no randomized clinical trials have evaluated the effect on bystander use automated external defibrillators (AEDs).To evaluate if AED could be increased by smartphone-aided lay with instructions collect AEDs compared go directly patients OHCAs start cardiopulmonary resuscitation (CPR).This trial assessed a system for smartphone individuals...
Abstract Aims Previous studies have indicated a poorer survival among women following out-of-hospital cardiac arrest (OHCA), but the mechanisms explaining this difference remain largely uncertain. This study aimed to assess after OHCA and men explore role of potential mediators, such as resuscitation characteristics, prior comorbidity, socioeconomic factors. Methods results was population-based cohort including emergency medical service-treated reported Swedish Registry for Cardiopulmonary...
Background: No practical tool quantitates the risk of circulatory-etiology death (CED) immediately after successful cardiopulmonary resuscitation in patients without ST-segment–elevation myocardial infarction. We developed and validated a prediction model to rapidly determine that facilitate triage individualized treatment pathways. Methods: With use INTCAR (International Cardiac Arrest Registry), an 87-question data set representing 44 centers United States Europe, were classified as having...
Abstract Background Therapeutic hypothermia (TH, 32-34°C) has been shown to improve neurological outcome in comatose survivors of out-of-hospital cardiac arrest (OHCA) with ventricular tachycardia or fibrillation. Earlier initiation TH may increase the beneficial effects. Experimental studies have suggested that starting during cardiopulmonary resuscitation (CPR) further enhance its neuroprotective The aim this study was evaluate whether intra-arrest (IATH), initiated field trans nasal...
<h3>Objectives:</h3> Unconscious patients represent a diagnostic challenge in the emergency room (ER), but studies on their characteristics are limited. The aim of this study was to investigate frequency, and prognosis different coma aetiologies with special focus poisoning. <h3>Design:</h3> An observational consecutive adults admitted non-surgical ER, Glasgow scale (GCS) score 10 or below. GCS admission prospectively entered into protocol, which complemented data from medical record within...
To determine the impact of a dual dispatch system, using fire fighters as first responders, in out-of-hospital cardiac arrest (OHCA) on short (30 days) and long term (three years) survival, and, to investigate potential differences regarding in-hospital factors interventions between patient groups, such use therapeutic hypothermia catheterization.OHCAs from 2004 (historical controls) 2006-2009 (intervention period) were included. During intervention period, equipped with automated external...
Delayed hypothermia, initiated after hospital arrival, several hours cardiac arrest with 8-10 to reach the target temperature, is likely have limited impact on overall survival. However, effect of ultrafast i.e. delivered intra-arrest or immediately return spontaneous circulation (ROSC), functional neurologic outcome out-of-hospital (OHCA) unclear. In two prior trials, prehospital trans-nasal evaporative cooling was safe, feasible and reduced time temperature compared delayed cooling. Both...
The aim of this study was to evaluate the implementation a novel extra corporeal cardiopulmonary (ECPR) program in greater Stockholm area with focus on feasibility, safety aspects and clinical outcomes. Prospective observational ECPR including patients OHCA from January 2020 December 2022, fulfilling criteria: age 18–65 years, initial shockable rhythm or pulseless electrical activity, witnessed arrest, bystander resuscitation refractory arrest after three cycles advance cardiac life support....
BACKGROUND: The ongoing TANGO2 (Telephone Assisted CPR. AN evaluation of efficacy amonGst cOmpression only and standard CPR) trial is designed to evaluate whether compression-only cardiopulmonary resuscitation (CPR) by trained laypersons noninferior CPR in adult out-of-hospital cardiac arrest. This pilot study assesses feasibility, safety, intermediate clinical outcomes as part the larger survival trial. METHODS: Emergency medical dispatch calls suspected arrest were screened for inclusion...
Abstract Background Randomized trials have shown that trans-nasal evaporative cooling initiated during CPR (i.e. intra-arrest) effectively lower core body temperature in out-of-hospital cardiac arrest patients. However, these may been underpowered to detect significant differences neurologic outcome, especially patients with initial shockable rhythm. Methods We conducted a post hoc pooled analysis of individual data from two randomized including 851 who eventually received the allocated...
Abstract Background Early defibrillation is critical for the chance of survival in out-of-hospital cardiac arrest (OHCA). Drones, used to deliver automated external defibrillators (AEDs), may shorten time defibrillation, but this has never been evaluated real-life emergencies. Purpose The aim study was investigate feasibility AED-delivery by drones cases OHCA. Methods In prospective clinical trial, three AED-equipped were placed within controlled airspace Sweden, covering approximately...
Time is the crucial factor in "chain of survival" treatment concept for out-of-hospital cardiac arrest (OHCA). We aimed to measure different response time intervals by comparing emergency medical system (EMS), fire fighters and smartphone aided volunteer responders.In two large Swedish regions, responders were timed from alert until they arrived at scene suspected OHCA. The first arriving who tried fetch an automated external defibrillator (AED-responder) ran perform bystander...