J. G. Smith

ORCID: 0000-0001-6285-9935
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About
Contact & Profiles
Research Areas
  • Particle physics theoretical and experimental studies
  • Quantum Chromodynamics and Particle Interactions
  • High-Energy Particle Collisions Research
  • Dark Matter and Cosmic Phenomena
  • Neutrino Physics Research
  • Genetic Associations and Epidemiology
  • Particle Detector Development and Performance
  • Cardiovascular Function and Risk Factors
  • Atrial Fibrillation Management and Outcomes
  • Cardiac Valve Diseases and Treatments
  • Heart Failure Treatment and Management
  • Particle Accelerators and Free-Electron Lasers
  • Cosmology and Gravitation Theories
  • Lipoproteins and Cardiovascular Health
  • Black Holes and Theoretical Physics
  • Acute Myocardial Infarction Research
  • Renal and related cancers
  • Bioinformatics and Genomic Networks
  • Cardiac electrophysiology and arrhythmias
  • Genomics and Rare Diseases
  • Renal cell carcinoma treatment
  • Atomic and Subatomic Physics Research
  • Cardiac Imaging and Diagnostics
  • Cardiomyopathy and Myosin Studies
  • Computational Physics and Python Applications

University of Washington
2014-2025

Skåne University Hospital
2016-2025

Lund University
2016-2025

Sahlgrenska University Hospital
2010-2025

University of Gothenburg
2020-2025

Science for Life Laboratory
2024

Clinical Research Institute
2024

Broad Institute
2013-2023

Center for Molecular Medicine and Immunology
2019-2023

Norfolk and Norwich University Hospital
2023

Based on the full BABAR data sample, we report improved measurements of ratios R(D(*))=B(B[over ¯]→D(*)τ(-)ν[over ¯](τ))/B(B[over ¯]→D(*)ℓ(ℓ)(-)ν[over ¯](ℓ)), where ℓ is either e or μ. These are sensitive to new physics contributions in form a charged Higgs boson. We measure R(D)=0.440±0.058±0.042 and R(D(*))=0.332±0.024±0.018, which exceed standard model expectations by 2.0σ 2.7σ, respectively. Taken together, our results disagree with these at 3.4σ level. This excess cannot be explained...

10.1103/physrevlett.109.101802 article EN publisher-specific-oa Physical Review Letters 2012-09-06

Based on the full BaBar data sample, we report improved measurements of ratios R(D(*)) = B(B -> D(*) Tau Nu)/B(B l Nu), where is either e or mu. These are sensitive to new physics contributions in form a charged Higgs boson. We measure R(D) 0.440 +- 0.058 0.042 and R(D*) 0.332 0.024 0.018, which exceed Standard Model expectations by 2.0 sigma 2.7 sigma, respectively. Taken together, our results disagree with these at 3.4 level. This excess cannot be explained boson type II two-Higgs-doublet...

10.1103/physrevd.88.072012 article EN Physical review. D. Particles, fields, gravitation, and cosmology/Physical review. D, Particles, fields, gravitation, and cosmology 2013-10-31

Searches for lepton-flavor-violating decays of a tau lepton to lighter mass and photon have been performed with the entire data set (963+/-7)x10{6} collected by BABAR detector near Upsilon(4S), Upsilon(3S) Upsilon(2S) resonances. The searches yield no evidence signals we upper limits on branching fractions B(tau{+/-}-->e{+/-}gamma)<3.3x10{-8} B(tau{+/-}-->mu{+/-}gamma)<4.4x10{-8} at 90% confidence level.

10.1103/physrevlett.104.021802 article EN Physical Review Letters 2010-01-14

Prior studies have demonstrated conflicting results regarding how much information novel biomarkers add to cardiovascular risk assessment.To evaluate the utility of contemporary for predicting when added conventional factors.Cohort study 5067 participants (mean age, 58 years; 60% women) without disease from Malmö, Sweden, who attended a baseline examination between 1991 and 1994. Participants underwent measurement C-reactive protein (CRP), cystatin C, lipoprotein-associated phospholipase 2,...

10.1001/jama.2009.943 article EN JAMA 2009-06-30

Using the CLEO II detector, we have measured differential cross sections for exclusive two-photon production of light pseudoscalar mesons ${\ensuremath{\pi}}^{0},$ \ensuremath{\eta}, and ${\ensuremath{\eta}}^{\ensuremath{'}}.$ From our measurements obtained form factors associated with electromagnetic transitions ${\ensuremath{\gamma}}^{*}\stackrel{\ensuremath{\rightarrow}}{\ensuremath{\gamma}}\mathrm{meson}.$ We these in momentum transfer ranges from 1.5 to 9, 20, $30{\mathrm{GeV}}^{2}$...

10.1103/physrevd.57.33 article EN Physical review. D. Particles, fields, gravitation, and cosmology/Physical review. D. Particles and fields 1998-01-01

Background Community screening to guide preventive interventions for acute aortic disease has been recommended in high‐risk individuals. We sought prospectively assess risk factors the general population dissection ( AD ) and severe aneurysmal thoracic abdominal aorta. Methods Results studied incidence of ruptured or surgically treated aneurysms AAA aorta TAA 30 412 individuals without diagnosis at baseline from a contemporary, prospective cohort middle‐aged individuals, Malmö Diet Cancer...

10.1161/jaha.114.001513 article EN cc-by-nc-nd Journal of the American Heart Association 2015-01-05

We search for single-photon events in 53 fb−1 of e+e− collision data collected with the BABAR detector at PEP-II B-Factory. look a single high-energy photon and large missing momentum energy, consistent production spin-1 particle A′ through process e+e−→γA′; A′→invisible. Such particles, referred to as "dark photons," are motivated by theories applying U(1) gauge symmetry dark matter. find no evidence such processes set 90% confidence level upper limits on coupling strength mass range mA′≤8...

10.1103/physrevlett.119.131804 article EN publisher-specific-oa Physical Review Letters 2017-09-28

This article reports world averages for measurements of b-hadron, c-hadron, and tau-lepton properties obtained by the Heavy Flavor Averaging Group (HFAG) using results available at least through end 2009. Some presented use data spring 2010. For averaging, common input parameters used in various analyses are adjusted (rescaled) to values, known correlations taken into account. The include branching fractions, lifetimes, neutral meson mixing parameters, CP violation semileptonic decays.

10.48550/arxiv.1010.1589 preprint EN other-oa arXiv (Cornell University) 2010-01-01

Transitions in the spectrum of valvular heart diseases (VHDs) developed countries over 20th century have been reported from clinical case series, but large, contemporary population-based studies are lacking.We used nationwide registers to identify all patients with a first diagnosis VHD at Swedish hospitals between 2003 and 2010. Age-stratified sex-stratified incidence each adjusted comorbidity profiles were assessed.In population (n=10 164 211), was 63.9 per 100 000 person-years, aortic...

10.1136/heartjnl-2016-310894 article EN cc-by-nc Heart 2017-04-21

Background: The cumulative burden and importance of cardiovascular risk factors have changed over the past decades. Specifically, obesity rates increased among younger people, whereas health has improved in elderly. Little is known regarding how these changes impacted incidence mortality heart failure. Therefore, we aimed to investigate age-specific trends 1-year following a first-time diagnosis failure Denmark between 1995 2012. Methods: We included all Danish individuals &gt;18 years age...

10.1161/circulationaha.116.025941 article EN Circulation 2017-02-08

Plasma low-density lipoprotein cholesterol (LDL-C) has been associated with aortic stenosis in observational studies; however, randomized trials cholesterol-lowering therapies individuals established valve disease have failed to demonstrate reduced progression.To evaluate whether genetic data are consistent an association between LDL-C, high-density (HDL-C), or triglycerides (TG) and disease.Using a Mendelian randomization study design, we evaluated weighted risk scores (GRSs), measure of...

10.1001/jama.2014.13959 article EN JAMA 2014-10-26

Many models of physics beyond the Standard Model predict existence new Abelian forces with gauge bosons mediating interactions between "dark sectors" and Model. We report a search for dark boson Z' coupling only to second third generations leptons in reaction e+e- -&gt; mu+mu- Z', using 514 fb-1 data collected by BABAR experiment. No significant signal is observed masses range 0.212 - 10 GeV. Limits on parameter g' as low 7x10^-4 are derived, leading improvements bounds compared those...

10.1103/physrevd.94.011102 article EN publisher-specific-oa Physical review. D/Physical review. D. 2016-07-19

Abstract Human gut microbiota produce a variety of molecules, some which enter the bloodstream and impact health. Conversely, dietary or pharmacological compounds may affect before entering circulation. Characterization these interactions is an important step towards understanding effects on In this cross-sectional study, we used deep metagenomic sequencing ultra-high-performance liquid chromatography linked to mass spectrometry for detailed characterization plasma metabolome, respectively,...

10.1038/s41467-022-33050-0 article EN cc-by Nature Communications 2022-09-23

BACKGROUND: Gut microbiota have been implicated in atherosclerotic disease, but their relation with subclinical coronary atherosclerosis is unclear. This study aimed to identify associations between the gut microbiome and computed tomography–based measures of explore relevant clinical correlates. METHODS: We conducted a cross-sectional 8973 participants (50 65 years age) without overt disease from population-based SCAPIS (Swedish Cardiopulmonary Bioimage Study). Coronary was measured using...

10.1161/circulationaha.123.063914 article EN cc-by Circulation 2023-07-12
Joshua S. Weinstock Jayakrishnan Gopakumar Bala Bharathi Burugula Md Mesbah Uddin Nikolaus Jahn and 95 more Julia A. Belk Hind Bouzid Bence Dániel Zhuang Miao Nghi Ly Taralynn Mack Sofia E. Luna Katherine P. Prothro Shaneice Mitchell Cecelia Laurie Jai Broome Kent D. Taylor Xiuqing Guo Moritz F. Sinner Aenne S. von Falkenhausen Stefan Kääb Alan R. Shuldiner Jeffrey R. O’Connell Joshua P. Lewis Eric Boerwinkle Kathleen C. Barnes Nathalie Chami Eimear E. Kenny Ruth J. F. Loos Myriam Fornage Lifang Hou Donald M. Lloyd‐Jones Susan Redline Brian E. Cade Bruce M. Psaty Joshua C. Bis Jennifer A. Brody Edwin K. Silverman Jeong H. Yun Dandi Qiao Colin N. A. Palmer Barry I. Freedman Donald W. Bowden Michael H. Cho Dawn L. DeMeo Ramachandran S. Vasan Lisa R. Yanek Lewis C. Becker Sharon L. R. Kardia Patricia A. Peyser Jiang He Michiel Rienstra Pim van der Harst Robert C. Kaplan Susan R. Heckbert Nicholas L. Smith Kerri L. Wiggins Donna K. Arnett Marguerite R. Irvin Hemant K. Tiwari Michael J. Cutler Stacey Knight J. Brent Muhlestein Adolfo Correa Laura M. Raffield Yan Gao Mariza de Andrade Jerome I. Rotter Stephen S. Rich Russell P. Tracy Barbara A. Konkle Jill M. Johnsen Marsha M. Wheeler J. G. Smith Olle Melander Peter M. Nilsson Brian Custer Ravindranath Duggirala Joanne E. Curran John Blangero Stephen T. McGarvey L. Keoki Williams Shujie Xiao Mao Yang C. Charles Gu Yii‐Der Ida Chen Wen‐Jane Lee Gregory M. Marcus John P. Kane Clive R. Pullinger M. Benjamin Shoemaker Dawood Darbar Dan M. Roden Christine M. Albert Charles Kooperberg Ying Zhou JoAnn E. Manson Pinkal Desai Andrew D. Johnson Rasika A. Mathias

10.1038/s41586-023-05806-1 article EN Nature 2023-04-12
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