Nasser Laouali
A5040235814- Nutritional Studies and Diet
- Nutrition, Genetics, and Disease
- Diet and metabolism studies
- Obesity, Physical Activity, Diet
- Consumer Attitudes and Food Labeling
- Heavy Metal Exposure and Toxicity
- Cancer Risks and Factors
- Cardiovascular Health and Risk Factors
- Trace Elements in Health
- Cancer, Lipids, and Metabolism
- Air Quality and Health Impacts
- Vitamin D Research Studies
- Fatty Acid Research and Health
- Folate and B Vitamins Research
- Hormonal and reproductive studies
- Vitamin C and Antioxidants Research
- Per- and polyfluoroalkyl substances research
- Agriculture Sustainability and Environmental Impact
- Biochemical Analysis and Sensing Techniques
- Antioxidant Activity and Oxidative Stress
- Liver Disease Diagnosis and Treatment
- Health, Environment, Cognitive Aging
- Adipokines, Inflammation, and Metabolic Diseases
- Tea Polyphenols and Effects
- Plant Micronutrient Interactions and Effects
Inserm
2018-2025
Centre de recherche en Epidémiologie et Santé des Populations
2018-2025
Université de Versailles Saint-Quentin-en-Yvelines
2018-2025
Université Paris-Saclay
2018-2025
University of Massachusetts Amherst
2021-2025
Université Mohammed VI Polytechnique
2024-2025
Institut Gustave Roussy
2020-2024
Scripps Institution of Oceanography
2021-2024
University of California, San Diego
2022-2024
Université Paris-Sud
2020-2024
Abstract Objective To investigate the association of plasma vitamin C and carotenoids, as indicators fruit vegetable intake, with risk type 2 diabetes. Design Prospective case-cohort study. Setting Populations from eight European countries. Participants 9754 participants incident diabetes, a subcohort 13 662 individuals Investigation into Cancer Nutrition (EPIC) cohort 340 234 participants: EPIC-InterAct Main outcome measure Incident Results In multivariable adjusted model, higher was...
OBJECTIVE Higher plasma vitamin C levels are associated with lower type 2 diabetes risk, but whether this association is causal uncertain. To investigate this, we studied the of genetically predicted diabetes. RESEARCH DESIGN AND METHODS We conducted genome-wide studies among 52,018 individuals European ancestry to discover novel genetic variants. performed Mendelian randomization analyses estimate differences in up 80,983 case participants and 842,909 noncase participants. compared...
Abstract Background Non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome (MetS) are implicated in the aetiology of non-communicable diseases. Our study aimed to evaluate associations between NAFLD MetS with overall cause-specific mortality. Methods We used dietary, lifestyle, anthropometric biomarker data from a random subsample 15,784 EPIC cohort participants. was assessed using index (FLI) revised definition. Indices for dysfunction–associated (MAFLD) were calculated. The...
Importance Adherence to the Mediterranean Diet (MedDiet) has been associated with a lower incidence of cancer and reduced weight gain. These associations suggest potential role for MedDiet in lowering risk obesity-related cancers (ORCs). Obesity is known factor various shows an inverse association adherence. Objective To examine between adherence ORCs, considering possible mediating adiposity. Design, Setting, Participants This prospective cohort study analyzed data from European Prospective...
OBJECTIVE There is sparse evidence for the association of suitable food substitutions red and processed meat on risk type 2 diabetes. We modeled between replacing with other protein sources diabetes estimated its population impact. RESEARCH DESIGN AND METHODS The European Prospective Investigation into Cancer (EPIC)-InterAct case cohort included 11,741 individuals a subcohort 15,450 participants in eight countries. replacement self-reported poultry, fish, eggs, legumes, cheese, cereals,...
BackgroundSince the first version of dietary inflammatory index (DII®) developed in past decade, several other versions have been developed. However, to date no study has attempted compare these with respect their associations biomarkers inflammation.ObjectiveWe aimed investigate relationship between four scores [DII, two energy-adjusted derivatives (E-DII and E-DIIr), Inflammatory Score Diet (ISD)], circulating levels markers adipokines.MethodsThis included 17 637 participants from European...
Abstract Background Epidemiological studies of associations between metabolites and cancer risk have typically focused on specific types separately. Here, we designed a multivariate pan-cancer analysis to identify potentially associated with multiple types, while also allowing the investigation type-specific associations. Methods We analysed targeted metabolomics data available for 5828 matched case-control pairs from cancer-specific breast, colorectal, endometrial, gallbladder, kidney,...
Abstract The role of dietary macronutrients and energy intake in the aging process has been well‐established. However, previous research mainly focused on association between leukocyte telomere length (LTL) individual macronutrients, while effects macronutrient composition LTL remain unclear. This cross‐sectional analysis involved 4130 US adults (44.8 ± 17.0 years; 51% female) from National Health Nutrition Examination Survey during 1999–2002. A single 24‐h recall is used to collect data....
Background: Folate is critical for many physiological processes, and low folate levels have been associated with a wide range of health outcomes, including chronic diseases developmental outcomes. Many environmental chemicals are suspected to contribute the etiology outcomes related deficiency. However, little known about how these pollutants influence as potential mechanistic pathways. Objective: To investigate individual joint associations between mixture 39 red blood cell (RBC)...
Diet is a modifiable risk factor for non-communicable diseases which are the major causes of death worldwide. French dietary guidelines, updated in 2017, provide recommendations healthier diet. We aimed to study association between adherence these guidelines and mortality E3N (Etude Epidémiologique auprès de femmes l'Education Nationale) cohort. A secondary objective was investigate role exposure chemical contaminants this association. studied 72 585 women prospective cohort, completed food...
Diet and obesity exhibit complex interrelationships with asthma, particularly among elderly women. We aimed to clarify the impact of healthy diet assessed by Alternate Healthy Eating Index-2010 (AHEI-2010) on: 1) incidence asthma symptoms, 2) women symptoms in 2011, change while accounting for potential mediating role BMI. A nested case-control study on follow-up data. Within French E3N cohort. 8621 (62 years average 1993). Dietary data were collected 1993 2005 using semi-quantitative...
Chronic exposure to heavy metals has been associated with adverse neurological outcomes in older adults. Inflammatory processes are suspected as an underlying pathway by which exert their neurotoxicity. In parallel, a diet rich antioxidant and anti-inflammatory components may protect against chronic inflammation.
Objectives The etiology of male breast cancer (MBC) is largely unknown but a causal role exposure to organic solvents has been suggested. Previous studies on occupational risk factors were often restricted women who are frequently exposed lower levels and at frequency than men. We investigated the association between MBC petroleum oxygenated chlorinated in multicenter case-control study rare cancers Europe. Methods included 104 cases 1901 controls. Detailed lifetime work history was obtained...
Abstract Introduction Previous studies have identified a positive association between the inflammatory potential of diet and hypertension. It is not known if BMI an effect modifier for this association, nor dose-respondent. This study aimed to assess dietary index (DII) risk hypertension, any modification from BMI. Methods Data E3N cohort study, French prospective population-based initiated in 1990 was used. From women we included those who completed detailed history questionnaire, did...
We investigated the impact of changes in lifestyle habits on colorectal cancer (CRC) risk a multicountry European cohort.