Woon‐Puay Koh
A5019713852- Nutritional Studies and Diet
- Diet and metabolism studies
- Liver Disease Diagnosis and Treatment
- Genetic Associations and Epidemiology
- Cancer, Lipids, and Metabolism
- Viral-associated cancers and disorders
- Folate and B Vitamins Research
- Cancer Risks and Factors
- Obesity, Physical Activity, Diet
- Nutrition and Health in Aging
- Nutrition, Genetics, and Disease
- Phytoestrogen effects and research
- Epigenetics and DNA Methylation
- Metabolomics and Mass Spectrometry Studies
- Respiratory viral infections research
- Global Cancer Incidence and Screening
- Diet, Metabolism, and Disease
- RNA modifications and cancer
- Fatty Acid Research and Health
- Cancer-related molecular mechanisms research
- Tea Polyphenols and Effects
- Telomeres, Telomerase, and Senescence
- Bone health and osteoporosis research
- Health disparities and outcomes
- Consumer Attitudes and Food Labeling
National University of Singapore
2016-2025
Agency for Science, Technology and Research
2020-2025
Singapore Institute for Clinical Sciences
2020-2025
Foundation for Human Potential
2025
Institute for Human Development
2025
Universiti Putra Malaysia
2025
National Cancer Council Malaysia
2025
Molecular Biology Consortium
2023
RIKEN Center for Integrative Medical Sciences
2023
Robert Bosch (Germany)
2023
Most studies that have evaluated the association between body-mass index (BMI) and risks of death from any cause specific causes been conducted in populations European origin.We performed pooled analyses to evaluate BMI risk among more than 1.1 million persons recruited 19 cohorts Asia. The included approximately 120,700 deaths occurred during a mean follow-up period 9.2 years. Cox regression models were used adjust for confounding factors.In East Asians, including Chinese, Japanese,...
An understanding of the etiologic heterogeneity ovarian cancer is important for improving prevention, early detection, and therapeutic approaches. We evaluated 14 hormonal, reproductive, lifestyle factors by histologic subtype in Ovarian Cancer Cohort Consortium (OC3).
<h3>Importance</h3> The role of ω-3 polyunsaturated fatty acids for primary prevention coronary heart disease (CHD) remains controversial. Most prior longitudinal studies evaluated self-reported consumption rather than biomarkers. <h3>Objective</h3> To evaluate biomarkers seafood-derived eicosapentaenoic acid (EPA; 20:5ω-3), docosapentaenoic (DPA; 22:5ω-3), and docosahexaenoic (DHA; 22:6ω-3) plant-derived α-linolenic (ALA; 18:3ω-3) incident CHD. <h3>Data Sources</h3> A global consortium 19...
Background The occurrence of diabetes has greatly increased in low- and middle-income countries, particularly Asia, as the prevalence overweight obesity; European-derived populations, obesity are established causes diabetes. shape association with risk its overall impact have not been adequately studied Asia. Methods Findings A pooled cross-sectional analysis was conducted to evaluate between baseline body mass index (BMI, measured weight kg divided by square height m) self-reported status...
The association between increasing body mass index (BMI; calculated as weight in kilograms divided by height meters squared) and risk of breast cancer is unique epidemiology that a crossover effect exists, with reduction before increase after menopause. inverse premenopausal poorly characterized but might be important the understanding causation.
Randomized controlled trials suggest that protein restriction may retard the progression of CKD toward ESRD. However, effects dietary intake level and food sources on risk ESRD in general population remain unclear. We investigated these Singapore Chinese Health Study, a prospective population-based cohort recruited 63,257 adults aged 45–74 years from 1993 to 1998. collected habitual diet information via validated semiquantitative frequency questionnaire identified record linkage with...
The association between long sleep duration and mortality appears stronger in East Asian populations than North American or European populations.To assess the sex-specific all-cause major-cause a pooled longitudinal cohort to stratify by age body mass index.This study of individual-level data from 9 cohorts Asia Cohort Consortium was performed January 1, 1984, December 31, 2002. final population included participants Japan, China, Singapore, Korea. Mean (SD) follow-up time 14.0 (5.0) years...
Colorectal cancer (CRC) is a major contributor to death globally. Several studies showed some protections by certain individual dietary antioxidants against CRC development. Epidemiologic data on the composite antioxidant index (CDAI) in relation risk are sparse. Using Singapore Chinese Health Study, an ongoing prospective cohort consisting of 61 321 cancer-free participants aged 45 74 years at baseline, food-based CDAI was calculated according previously established and validated method...
Despite evidence of an association between reproductive factors and endometrial cancer risk, prospective studies have been conducted mainly in non-Asian countries.To assess the factors, such as number deliveries, age at menarche, or menopause, risk.This cohort study used pooled individual data from 13 1963 2014 Asia Cohort Consortium. Participants were Asian women. Data analysis was September 2019 to April 2023.Reproductive assessed using a questionnaire each cohort.The main outcome time...
Epidemiologic studies have shown that daily exposure to incense smoke is associated with greater risk of cardiovascular mortality, which suggests chronic could be linked atherosclerosis. We studied the association between home use and limb-threatening ischemia (CLTI), most severe outcome peripheral arterial disease. used data from Singapore Chinese Health Study, recruited 63,257 participants 45-74 years old 1993-1998. Data were collected via in-person interviews conducted at participants'...