Thomas Merlijn
A5059886631- Bone health and osteoporosis research
- Hip and Femur Fractures
- Bone and Joint Diseases
- Bone fractures and treatments
- Vitamin D Research Studies
- Clinical practice guidelines implementation
- Hip disorders and treatments
- Bone health and treatments
- Nutritional Studies and Diet
- Balance, Gait, and Falls Prevention
- Emergency and Acute Care Studies
- Rheumatoid Arthritis Research and Therapies
- Stroke Rehabilitation and Recovery
- Musculoskeletal pain and rehabilitation
- Bone Metabolism and Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Cerebral Palsy and Movement Disorders
- Healthcare cost, quality, practices
- Traffic Prediction and Management Techniques
- Risk and Safety Analysis
Amsterdam University Medical Centers
2019-2025
University of Amsterdam
2023-2025
Amsterdam University of Applied Sciences
2024
Huisarts en Wetenschap
2024
Phoenix Contact (United States)
2024
Amsterdam UMC Location VUmc
2010-2022
Vrije Universiteit Amsterdam
2019-2020
ABSTRACT Population screening for fracture risk may reduce the incidence. In this randomized pragmatic trial, SALT Osteoporosis Study (SOS), we studied whether and subsequent treatment in primary care can fractures compared with usual care. A total of 11,032 women aged 65 to 90 years ≥1 clinical factor were individually (n = 5575) or 5457). Participants group underwent a program, including bone densitometry vertebral assessment. high 10-year probability (FRAX) offered anti-osteoporosis...
We developed an externally validated simple prediction model to predict serum 25(OH)D levels < 30, 40, 50 and 60 nmol/L in older women with risk factors for fractures. The benefit of the reduces when a higher threshold is chosen. Vitamin D deficiency associated increased fracture persons. General supplementation all vitamin could cause medicalization costs. clinical identify insufficient 25-hydroxyvitamin (25(OH)D) status at In sample 2689 ≥ 65 years selected from general practices, least...
This study evaluated the yield of routine laboratory examination in a large population older women primary care. The prevalence abnormalities was low and clinical consequences follow-up were limited. There weak association with osteoporosis but no vertebral fractures recent fractures.
Several drugs have become available for the treatment of osteoporosis. However, screening and patients with a high fracture risk is currently not recommended in Netherlands, because effectiveness bone sparing has been demonstrated general primary care population. Here we describe design SALT Osteoporosis study, which aims to examine whether older, female can reduce fractures, comparison usual care. A randomised pragmatic trial designed using stepwise approach practices Netherlands. Women...