- Bone health and osteoporosis research
- Hip and Femur Fractures
- Birth, Development, and Health
- Vitamin D Research Studies
- Bone health and treatments
- Bone Metabolism and Diseases
- Hip disorders and treatments
- Pregnancy and preeclampsia studies
- Nutrition and Health in Aging
- Bone fractures and treatments
- Obesity, Physical Activity, Diet
- Gestational Diabetes Research and Management
- Bone and Joint Diseases
- Body Composition Measurement Techniques
- Nutritional Studies and Diet
- Rheumatoid Arthritis Research and Therapies
- Folate and B Vitamins Research
- Cardiac Imaging and Diagnostics
- Osteoarthritis Treatment and Mechanisms
- Epigenetics and DNA Methylation
- Frailty in Older Adults
- Vitamin C and Antioxidants Research
- Pregnancy and Medication Impact
- Cardiovascular Disease and Adiposity
- Cardiac, Anesthesia and Surgical Outcomes
MRC Lifecourse Epidemiology Unit
2016-2025
Southampton General Hospital
2016-2025
NIHR Southampton Biomedical Research Centre
2016-2025
University Hospital Southampton NHS Foundation Trust
2016-2025
University of Southampton
2016-2025
University Hospitals of Leicester NHS Trust
2008-2025
University of Gothenburg
2017-2025
Glenfield Hospital
2009-2025
Medical Research Council
2015-2024
National Institute for Health Research
2015-2024
In 2008, the UK National Osteoporosis Guideline Group (NOGG) produced a guideline on prevention and treatment of osteoporosis, with an update in 2013. This paper presents major guideline, scope which is to review assessment management osteoporosis fragility fractures postmenopausal women men age 50 years or over. Where available, systematic reviews, meta-analyses randomised controlled trials were used provide evidence base. Conclusions recommendations systematically graded according strength...
Abstract Summary This report provides an overview and a comparison of the burden management fragility fractures in largest five countries European Union plus Sweden (EU6). In 2017, new EU6 are estimated at 2.7 million with associated annual cost €37.5 billion loss 1.0 quality-adjusted life years. Introduction Osteoporosis is characterized by reduced bone mass strength, which increases risk fractures, turn, represent main consequence disease. EU (designated EU6). Methods A series metrics...
This scorecard summarises key indicators of the burden osteoporosis and its management in 27 member states European Union, as well UK Switzerland. The resulting elements, assembled on a single sheet, provide unique overview Europe.The for Europe (SCOPE) is project International Osteoporosis Foundation (IOF) that seeks to raise awareness care Europe. aim this was develop background documents draw attention gaps inequalities provision primary secondary prevention fractures due osteoporosis.The...
Little is known about preschool-aged children’s levels of physical activity (PA) over the course day. Using time-stamped data, we describe and patterns PA in a population-based sample four-year-old British children. Within Southampton Women’s Survey 593 4-year-old children (51% female) were measured using (Actiheart) accelerometry for up to 7 days. Three outcome measures: minutes spent sedentary (<20 cpm); light (LPA: ≥20 – 399 cpm) moderate-to-vigorous (MVPA: ≥400 derived. Average daily...
Abstract Background We examined whether the greater severity of coronavirus disease 2019 (COVID-19) amongst men and Black, Asian Minority Ethnic (BAME) individuals is explained by cardiometabolic, socio-economic or behavioural factors. Methods studied 4510 UK Biobank participants tested for COVID-19 (positive, n = 1326). Multivariate logistic regression models including age, sex ethnicity were used to test addition (1) cardiometabolic factors [diabetes, hypertension, high cholesterol, prior...